Výsledky vyhledávání - "Melissa P. M. Stropes"

Activation of Intracellular Signaling Pathways by the Murine Cytomegalovirus G Protein-Coupled Receptor M33 Occurs via PLC-β/PKC-Dependent and -Independent Mechanisms

Autor: William E. Miller, Fabiola M. Bittencourt, Diana E. Koch, Melissa P. M. Stropes, Joseph D. Sherrill, Olivia D. Schneider, Jeanette L. C. Miller

Publikováno v: Journal of Virology. 83:8141-8152

The presence of numerous G protein-coupled receptor (GPCR) homologs within the herpesvirus genomes suggests an essential role for these genes in viral replication in the infected host. Such is the case for murine cytomegalovirus (MCMV), where deletio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f944a5aaed64e06fc9b6462478a31d2
https://doi.org/10.1128/jvi.02116-08

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The carboxy-terminal tail of human cytomegalovirus (HCMV) US28 regulates both chemokine-independent and chemokine-dependent signaling in HCMV-infected cells

Autor: Olivia D. Schneider, Jeanette L. C. Miller, William A. Zagorski, Melissa P. M. Stropes, William E. Miller

Publikováno v: Journal of virology. 83(19)

The human cytomegalovirus (HCMV)-encoded G-protein-coupled receptor (GPCR) US28 is a potent activator of a number of signaling pathways in HCMV-infected cells. The intracellular carboxy-terminal domain of US28 contains residues critical for the regul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77783de398f3e0690738a376a37bc6bb
https://pubmed.ncbi.nlm.nih.gov/19605482

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Functional analysis of human cytomegalovirus pUS28 mutants in infected cells

Autor: Melissa P. M. Stropes, William E. Miller

The human cytomegalovirus (HCMV)-encoded viral G protein-coupled receptor pUS28 contributes to an array of biological effects, including cell migration and proliferation. Using FIX-BAC (bacterial artificial chromosome, derived from the HCMV clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2449dd7f2683561ace93449149dfe3af
https://europepmc.org/articles/PMC2662737/

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Signaling and regulation of G-protein coupled receptors encoded by cytomegaloviruses

Autor: William E. Miller, Melissa P. M. Stropes

Publikováno v: Biochemistry and cell biology = Biochimie et biologie cellulaire. 82(6)

Cytomegaloviruses (CMVs) are species-specific β-herpesviruses whose replicative success is largely due to establishment of novel mechanisms for altering the host immune response. CMV encodes 3 families of putative G-protein coupled receptors (GPCRs)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9d1063401d6a50282b49f7f2cab3754
https://pubmed.ncbi.nlm.nih.gov/15674431

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