Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Melissa Mun"'
Air sparging for prevention of antibody disulfide bond reduction in harvested CHO cell culture fluid
Autor:
Michael W. Laird, Melissa Mun, Melody Trexler-Schmidt, James Dvornicky, Yung-Hsiang Kao, Stefanie Khoo, Aline Do Minh
Publikováno v:
Biotechnology and Bioengineering. 112:734-742
During the scale-up of several Chinese Hamster Ovary (CHO) cell monoclonal antibody production processes, significant reduction of the antibody interchain disulfide bonds was observed. The reduction was correlated with excessive mechanical cell shear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ced097672e49e0a33ed5565ecfa502f2
https://doi.org/10.1002/bit.25495
https://doi.org/10.1002/bit.25495
Autor:
Jun Egawa, Reza K. Arta, Vance P. Lemmon, Melissa Muños-Barrero, Yan Shi, Michihiro Igarashi, Toshiyuki Someya
Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-5 (2022)
Abstract Protein kinases are responsible for protein phosphorylation and are involved in important signal transduction pathways; however, a considerable number of poorly characterized kinases may be involved in neuronal development. Here, we consider
Externí odkaz:
https://doaj.org/article/7a5657b35acb4c48aad0a7a846d298cd
Autor:
Andrea D. Guastello, Corey Lieneman, Brittany Bailey, Melissa Munson, Megan Barthle-Herrera, Miranda Higham, Lindsay Druskin, Cheryl B. McNeil
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
This fictionalized case report captures the common themes and considerations during the diagnostic assessment and behavioral treatment of adolescents demonstrating symptoms of autism spectrum disorder (ASD), obsessive-compulsive disorder (OCD), and a
Externí odkaz:
https://doaj.org/article/1471b4b9ca464bd79e234bf2b4362151
Air sparging for prevention of antibody disulfide bond reduction in harvested CHO cell culture fluid
Autor:
Melissa, Mun, Stefanie, Khoo, Aline, Do Minh, James, Dvornicky, Melody, Trexler-Schmidt, Yung-Hsiang, Kao, Michael W, Laird
Publikováno v:
Biotechnology and bioengineering. 112(4)
During the scale-up of several Chinese Hamster Ovary (CHO) cell monoclonal antibody production processes, significant reduction of the antibody interchain disulfide bonds was observed. The reduction was correlated with excessive mechanical cell shear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e1d1f2c507f02d37bca28f6373180ba5
https://pubmed.ncbi.nlm.nih.gov/25384896
https://pubmed.ncbi.nlm.nih.gov/25384896
Autor:
Boyan Zhang, Natarajan Vijayasankaran, Robert Kiss, Steve Meier, Yi Yang, Amy Lim, Martin Gawlitzek, Feng Li, Sharat Varma, Melissa Mun, Silvana R. Arevalo, Trevor E. Swartz
Publikováno v:
Biotechnology progress. 29(5)
As the industry moves toward subcutaneous delivery as a preferred route of drug administration, high drug substance concentrations are becoming the norm for monoclonal antibodies. At such high concentrations, the drug substance may display a more int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7024764cbe1169772f115cc58c0a7cba
https://pubmed.ncbi.nlm.nih.gov/23804462
https://pubmed.ncbi.nlm.nih.gov/23804462
Publikováno v:
Molecular biotechnology. 45(3)
The goal of quality by design (QbD) in cell culture manufacturing is to develop manufacturing processes which deliver products with consistent critical quality attributes (CQAs). QbD approaches can lead to better process understanding through the use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c6e747731edcb219f10763062bd1c51
https://pubmed.ncbi.nlm.nih.gov/20300882
https://pubmed.ncbi.nlm.nih.gov/20300882
Publikováno v:
Horticulturae, Vol 9, Iss 6, p 646 (2023)
Cut roses are highly valuable ornamentals and their profitability depends on the flower postharvest performance. Bent neck symptoms in roses make them unmarketable and are typically related to physiological disorders, bacteria accumulation in the vas
Externí odkaz:
https://doaj.org/article/8a0a56be690647549117bccdd96ee565
Autor:
Yony Fernando Ceballos, Sebastían Penagos-Arroyave, Verónica Vanessa García-García, Melissa Munera-Pulgarín
Publikováno v:
AiBi Revista de Investigación, Administración e Ingeniería, Vol 10, Iss 1 (2022)
El uso de la simulación permite a una compañía el entendimiento de sus procesos y, mediante la modelación de sus problemas encontrar soluciones que se ajusten a sus necesidades y que les permita tomar medidas correctivas para que sus procesos sea
Externí odkaz:
https://doaj.org/article/01451d19ffd249cb8fcf70f6c65c3dba
Autor:
Gabriela Toomer, Whitney Burns, Liliana Garcia, Gerelyn Henry, Anthony Biancofiori, Albert George, Ciera Duffy, Justin Chu, Morgan Sides, Melissa Muñoz, Kelly Garcia, Anya Nikolai-Yogerst, Xinjian Peng, Landon Westfall, Robert Baker
Publikováno v:
Viruses, Vol 14, Iss 11, p 2584 (2022)
Animal models are used in preclinical trials to test vaccines, antivirals, monoclonal antibodies, and immunomodulatory drug therapies against SARS-CoV-2. However, these drugs often do not produce equivalent results in human clinical trials. Here, we
Externí odkaz:
https://doaj.org/article/7cc0d750b793453680e5494f5b2bbb1e
Autor:
Eleonora Rodríguez-Polanco, Juan G. Morales, Melissa Muñoz-Agudelo, José D. Segura, Martha L. Carrero
Publikováno v:
Spanish Journal of Agricultural Research, Vol 18, Iss 2, Pp e1003-e1003 (2020)
Aim of study: To characterize isolates of Phytophthora sp. causing black pod rot (BPR) of cacao (Theobroma cacao L.). Area of study: Eight cocoa-growing regions in Colombia. Material and methods: Sixty isolates of Phytophthora sp. were obtained fro
Externí odkaz:
https://doaj.org/article/5d64c8a98ffc4e37856b42f8ee836d8d