Výsledky vyhledávání - "Melissa Muff‐Luett"

Akademický článek

Ravulizumab in Atypical Hemolytic Uremic Syndrome: An Analysis of 2-Year Efficacy and Safety Outcomes in 2 Phase 3 Trials

Autor: Bradley P. Dixon, David Kavanagh, Alvaro Domingo Madrid Aris, Brigitte Adams, Hee Gyung Kang, Edward Wang, Katherine Garlo, Masayo Ogawa, Praveen Amancha, Sourish Chakravarty, Nils Heyne, Seong Heon Kim, Spero Cataland, Sung-Soo Yoon, Yoshitaka Miyakawa, Yosu Luque, Melissa Muff-Luett, Kazuki Tanaka, Larry A. Greenbaum

Publikováno v: Kidney Medicine, Vol 6, Iss 8, Pp 100855- (2024)

Rationale & Objective: Atypical hemolytic uremic syndrome (aHUS) is a rare form of thrombotic microangiopathy (TMA) caused by complement dysregulation. Ravulizumab is a C5i approved for the treatment of aHUS. This analysis assessed long-term outcomes

Externí odkaz: https://doaj.org/article/7f561a99f7394b13a825a873ba0b2526

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Akademický článek

Clinical presentation and management of nephrotic syndrome in the first year of life: A report from the Pediatric Nephrology Research Consortium

Autor: Alexandru R. Constantinescu, Tej K. Mattoo, William E. Smoyer, Larry A. Greenbaum, Jianli Niu, Noel Howard, Melissa Muff-Luett, Elizabeth B. Benoit, Avram Traum, Ali A. Annaim, Scott E. Wenderfer, Emilee Plautz, Michelle N. Rheault, Robert L. Myette, Katherine E. Twombley, Yu Kamigaki, Belkis Wandique-Rapalo, Mohammad Kallash, Tetyana L. Vasylyeva

Publikováno v: Frontiers in Pediatrics, Vol 10 (2022)

Background and objectivesNephrotic syndrome (NS) in the first year of life is called congenital (CNS) if diagnosed between 0–3 months, or infantile (INS) if diagnosed between 3–12 months of age. The aim of this study was to determine if there wer

Externí odkaz: https://doaj.org/article/2c81f7d437a546a6b74c2da321434120

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Akademický článek

Diagnosis, Treatment, and Outcomes in Children With Congenital Nephrogenic Diabetes Insipidus: A Pediatric Nephrology Research Consortium Study

Autor: Cynthia D'Alessandri-Silva, Melinda Carpenter, Rose Ayoob, John Barcia, Aftab Chishti, Alex Constantinescu, Katherine M. Dell, Julie Goodwin, Shireen Hashmat, Sandra Iragorri, Cristin Kaspar, Sherene Mason, Jason M. Misurac, Melissa Muff-Luett, Christine Sethna, Shweta Shah, Patricia Weng, Larry A. Greenbaum, John D. Mahan

Publikováno v: Frontiers in Pediatrics, Vol 7 (2020)

Background and Objectives: Congenital or primary nephrogenic diabetes insipidus (NDI) is a rare genetic disorder that severely impairs renal concentrating ability, resulting in massive polyuria. There is limited information about prognosis or evidenc

Externí odkaz: https://doaj.org/article/c089f2fec25b4b71a6610cdc67f57ed6

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A comparison of the buttonhole and rope-ladder AVF cannulation techniques and infection rates within the SCOPE collaborative

Autor: Heather A, Morgans, Heidi Gruhler, De Souza, Troy, Richardson, Donna, Claes, Kevin T, Barton, Marsha, Lee, Shefali, Mahesh, Melissa, Muff-Luett, Sarah J, Swartz, Alicia, Neu, Bradley, Warady

Publikováno v: Pediatric nephrology (Berlin, Germany). 36(12)

Studies regarding hemodialysis (HD) arteriovenous fistula (AVF) cannulation in adults indicate a higher risk of infection with the buttonhole (BH) technique compared to the rope-ladder (RL) technique. Pediatric data on this issue is sparse.We compare

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a2b76305a9c0d5c2e8db19dc011ba5e7
https://pubmed.ncbi.nlm.nih.gov/34115208

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Two-Year Efficacy and Safety of Ravulizumab in Adults and Children with Atypical Hemolytic Uremic Syndrome (aHUS): Analysis of Two Phase 3 Studies

Autor: Alvaro Domingo Madris-Aris, Katherine Garlo, Laurence Greenbaum, Seong Heon Kim, Melissa Muff-Luett, David J. Kavanagh, Brigitte Adams, Yosu Luque, Spero R. Cataland, Jimmy Wang, Sung-Soo Yoon, Bradley P. Dixon, Masayo Ogawa, Kazuki Tanaka, Hee Gyung Kang, Nils Heyne, Yoshitaka Miyakawa

Publikováno v: Blood. 138:769-769

Background Ravulizumab, a humanized anti-complement C5 monoclonal antibody designed by targeted modification of eculizumab to achieve an extended half-life, is approved to treat aHUS in the USA (2019), EU and Japan (2020). Data at 26 weeks (wk) and 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5f33ea3938c3ed6788e67ec01c9b8b64
https://doi.org/10.1182/blood-2021-145040

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The Genetics of Ultra-Rare Renal Disease

Autor: Carla M. Nester, Melissa Muff-Luett

Publikováno v: Journal of pediatric genetics. 5(1)

The complement-mediated renal diseases are a group of ultra-rare renal diseases that disproportionately affect children and young adults and frequently lead to irreversible renal failure. Genetic mutations in alternate pathway of complement genes are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e878881eb4ade503836b68de70e281a0
https://pubmed.ncbi.nlm.nih.gov/27617140

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