Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Melissa McDougall"'
Autor:
Melissa McDougall, Jaewoo Choi, Hye–Kyeong Kim, Gerd Bobe, J. Frederik Stevens, Enrique Cadenas, Robert Tanguay, Maret G. Traber
Publikováno v:
Data in Brief, Vol 11, Iss C, Pp 432-441 (2017)
The data herein is in support of our research article by McDougall et al. (2017) [1], in which we used our zebrafish model of embryonic vitamin E (VitE) deficiency to study the consequences of VitE deficiency during development. Adult 5D wild-type ze
Externí odkaz:
https://doaj.org/article/1b26127e5242407f90309a702d7c1ce1
Autor:
Jaewoo Choi, Scott W. Leonard, Katherine Kasper, Melissa McDougall, Jan F. Stevens, Robert L. Tanguay, Maret G. Traber
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 6, Pp 1182-1190 (2015)
We hypothesized that brains from vitamin E-deficient (E−) zebrafish (Danio rerio) would undergo increased lipid peroxidation because they contain highly polyunsaturated fatty acids, thus susceptible lipids could be identified. Brains from zebrafish
Externí odkaz:
https://doaj.org/article/66ca9eb8f42d45e4b1bb2c2358eee3da
Autor:
Robert L. Tanguay, Melissa McDougall, Maret G. Traber, Hye Kyeong Kim, Enrique Cadenas, J. Frederik Stevens, Jaewoo Choi, Gerd Bobe
Publikováno v:
Data in Brief, Vol 11, Iss C, Pp 432-441 (2017)
Data in Brief
Data in Brief
The data herein is in support of our research article by McDougall et al. (2017) [1], in which we used our zebrafish model of embryonic vitamin E (VitE) deficiency to study the consequences of VitE deficiency during development. Adult 5D wild-type ze
Autor:
Jaewoo Choi, Melissa McDougall, Gerd Bobe, Maret G. Traber, Robert L. Tanguay, Hye-Kyeong Kim, Enrique Cadenas, J. Frederik Stevens
Publikováno v:
Free Radical Biology and Medicine. 104:324-332
Vitamin E (α-tocopherol, VitE) was discovered in 1922 for its role in preventing embryonic mortality. We investigated the underlying mechanisms causing lethality using targeted metabolomics analyses of zebrafish VitE-deficient embryos over five days
Autor:
Maret G. Traber, Melissa McDougall, Lisa Truong, Jan F. Stevens, Robert L. Tanguay, Jaewoo Choi
Publikováno v:
Redox Biology, Vol 8, Iss C, Pp 165-174 (2016)
Redox Biology
Redox Biology
We hypothesized that vitamin E (α-tocopherol) is required by the developing embryonic brain to prevent depletion of highly polyunsaturated fatty acids, especially docosahexaenoic acid (DHA, 22:6), the loss of which we predicted would underlie abnorm
Autor:
Melissa McDougall, Jan F. Stevens, Katherine Kasper, Scott W. Leonard, Robert L. Tanguay, Maret G. Traber, Jaewoo Choi
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 6, Pp 1182-1190 (2015)
We hypothesized that brains from vitamin E-deficient (E-) zebrafish (Danio rerio) would undergo increased lipid peroxidation because they contain highly polyunsaturated fatty acids, thus susceptible lipids could be identified. Brains from zebrafish f
Autor:
Robert L. Tanguay, Maret G. Traber, Kathy R. Magnusson, Lisa Truong, Melissa McDougall, Jaewoo Choi
Zebrafish (Danio rerio) are a recognized model for studying the pathogenesis of cognitive deficits and the mechanisms underlying behavioral impairments, including the consequences of increased oxidative stress within the brain. The lipophilic antioxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d37c4e4b2b97e32e21af84b674f691
https://europepmc.org/articles/PMC5629005/
https://europepmc.org/articles/PMC5629005/
Publikováno v:
Free radical biologymedicine. 110
Vitamin E (α-tocopherol; VitE) is a lipophilic antioxidant required for normal embryonic development in vertebrates, but the long-term effects of embryonic VitE deficiency, and whether they are ameliorated by feeding VitE-adequate diets, remain unkn
Autor:
Enrique Cadenas, J. Frederik Stevens, Hye-Kyeong Kim, Melissa McDougall, Maret G. Traber, Jaewoo Choi, Gerd Bobe, Robert L. Tanguay
Publikováno v:
Free Radical Biology and Medicine. 108:S2
Vitamin E (α-tocopherol, VitE) was discovered in 1922 because it prevented rat fetal resorption. We investigated the mechanisms causing lethality using targeted metabolomic analyses of zebrafish VitE-deficient embryos daily from 1 to 5 days by which
Autor:
Robert L. Tanguay, Jaewoo Choi, Maret G. Traber, Hye-Kyeong Kim, Melissa McDougall, Enrique Cadenas
Publikováno v:
Free Radical Biology and Medicine. 100:S105
Vitamin E (VitE), a lipophilic antioxidant, prevents fetal resorption in VitE-deficient pregnant rodents. However, the mechanism for this requirement is unknown. We explored the underlying cause of mortality during developmental VitE deficiency using