Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Melissa M. Matzke"'
Autor:
Bobbie-Jo M. Webb-Robertson, Melissa M. Matzke, Thomas O. Metz, Jason E. McDermott, Hyunjoo Walker, Karin D. Rodland, Joel G. Pounds, Katrina M. Waters
Publikováno v:
BioTechniques, Vol 54, Iss 3, Pp 165-168 (2013)
Principal Component Analysis (PCA) is a common exploratory tool used to evaluate large complex data sets. The resulting lower-dimensional representations are often valuable for pattern visualization, clustering, or classification of the data. However
Externí odkaz:
https://doaj.org/article/a1de042aafd440ff8b632929f3bae117
Autor:
Ernesto S. Nakayasu, Carrie D. Nicora, Amy C. Sims, Kristin E. Burnum-Johnson, Young-Mo Kim, Jennifer E. Kyle, Melissa M. Matzke, Anil K. Shukla, Rosalie K. Chu, Athena A. Schepmoes, Jon M. Jacobs, Ralph S. Baric, Bobbie-Jo Webb-Robertson, Richard D. Smith, Thomas O. Metz
Publikováno v:
mSystems, Vol 1, Iss 3 (2016)
ABSTRACT Integrative multi-omics analyses can empower more effective investigation and complete understanding of complex biological systems. Despite recent advances in a range of omics analyses, multi-omic measurements of the same sample are still ch
Externí odkaz:
https://doaj.org/article/6bfbb8695fd0439ea537209e08d93cb9
Autor:
Vineet D. Menachery, Amie J. Eisfeld, Alexandra Schäfer, Laurence Josset, Amy C. Sims, Sean Proll, Shufang Fan, Chengjun Li, Gabriele Neumann, Susan C. Tilton, Jean Chang, Lisa E. Gralinski, Casey Long, Richard Green, Christopher M. Williams, Jeffrey Weiss, Melissa M. Matzke, Bobbie-Jo Webb-Robertson, Athena A. Schepmoes, Anil K. Shukla, Thomas O. Metz, Richard D. Smith, Katrina M. Waters, Michael G. Katze, Yoshihiro Kawaoka, Ralph S. Baric
Publikováno v:
mBio, Vol 5, Iss 3 (2014)
ABSTRACT The broad range and diversity of interferon-stimulated genes (ISGs) function to induce an antiviral state within the host, impeding viral pathogenesis. While successful respiratory viruses overcome individual ISG effectors, analysis of the g
Externí odkaz:
https://doaj.org/article/758ade4ede57407c9376f7e42de78b98
Autor:
David L. Stenoien, Melissa M. Matzke, William F. Morgan, Susan C. Tilton, Katrina M. Waters, Thomas J. Weber, Marianne B. Sowa
Publikováno v:
Toxicology and Applied Pharmacology. 285(1):1-11
The goal of this study was to define pathways regulated by low dose radiation to understand how biological systems respond to subtle perturbations in their environment and prioritize pathways for human health assessment. Using an in vitro 3-D human f
Autor:
Richard D. Smith, Renuka Bhattacharya, John D. Sandoval, Kevin L. Crowell, Deborah L. Diamond, Steven G. Self, Gordon W. Slysz, Kristin E. Burnum-Johnson, Yehia M. Ibrahim, Susan Strom, William F. Danielson, Paul D. Piehowski, Daniel J. Orton, Marina A. Gritsenko, Brian L. LaMarche, Brian J. McMahon, Matthew E. Monroe, Brenna C. Simons, Robert L. Carithers, Melissa M. Matzke, Ronald J. Moore, David E. Purdy, Roslyn N. Brown, James D. Perkins, Jon M. Jacobs, Erin S. Baker, Gordon A. Anderson, Bobbie-Jo M. Webb-Robertson, Michael G. Katze
Publikováno v:
Molecular & Cellular Proteomics. 13:1119-1127
Rapid diagnosis of disease states using less invasive, safer, and more clinically acceptable approaches than presently employed is a crucial direction for the field of medicine. While MS-based proteomics approaches have attempted to meet these object
Autor:
Kim A. Anderson, Andrea L. Knecht, Melissa M. Matzke, Annika J. Swanson, Katrina M. Waters, Michael Simonich, Lisa Truong, Britton C. Goodale, Robert L. Tanguay
Publikováno v:
Toxicology and Applied Pharmacology. 271:266-275
Oxygenated polycyclic aromatic hydrocarbons (OPAHs) are byproducts of combustion and photo-oxidation of parent PAHs. OPAHs are widely present in the environment and pose an unknown hazard to human health. The developing zebrafish was used to evaluate
Autor:
Michael R. Blackburn, Melissa M. Matzke, Jing Wang, Karin D. Rodland, Bobbie-Jo M. Webb-Robertson, Roderick M. Riensche, Mary Beth Scholand, Joel G. Pounds, Jason E. McDermott, John R. Hoidal, Joshua N. Adkins, Jon M. Jacobs, Joseph N. Brown, Susan M. Varnum
Publikováno v:
Disease Markers, Vol 35, Iss 5, Pp 513-523 (2013)
Disease markers
Disease markers
Background. The availability of large complex data sets generated by high throughput technologies has enabled the recent proliferation of disease biomarker studies. However, a recurring problem in deriving biological information from large data sets
Publikováno v:
Environmental Toxicology and Chemistry. 31:2888-2892
The use of passive sampling devices (PSDs) for monitoring hydrophobic organic contaminants in aquatic environments can entail logistical constraints that often limit a comprehensive statistical sampling plan, thus resulting in a restricted number of
Autor:
David E. Williams, Lyndsey E. Shorey, David J. Castro, Richard A. Corley, Melissa M. Matzke, Christiane V. Löhr, Katrina M. Waters, Lisbeth K. Siddens, William M. Baird
Publikováno v:
Cancer Letters. 317:49-55
Dibenzo[def,p]chrysene (DBC) is a transplacental carcinogen in mice (15mg/kg; gestation day (GD) 17). To mimic residual exposure throughout pregnancy, dams received four smaller doses of DBC (3.75mg/kg) on GD 5, 9, 13 and 17. This regimen alleviated
Autor:
Katrina M. Waters, Joel G. Pounds, Jon M. Jacobs, Melissa M. Matzke, Bobbie-Jo M. Webb-Robertson
Publikováno v:
PROTEOMICS. 11:4736-4741
Quantification of LC-MS peak intensities assigned during peptide identification in a typical comparative proteomics experiment will deviate from run-to-run of the instrument due to both technical and biological variation. Thus, normalization of peak