Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Melissa M. Brierley"'
Publikováno v:
FEBS Journal. 273:1569-1581
Signal transducer and activator of transcription 2 (STAT2) is best known as a critical transactivator component of the interferon-stimulated gene factor 3 (ISGF3) complex that drives the expression of many interferon (IFN)-inducible genes. However, S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b153764e020091a8235031dc2b804d4
https://doi.org/10.1111/j.1742-4658.2006.05176.x
https://doi.org/10.1111/j.1742-4658.2006.05176.x
Autor:
Eleanor N. Fish, Melissa M. Brierley
Publikováno v:
Journal of Interferon & Cytokine Research. 22:835-845
Type I interferons (IFNs), which include the IFN-alphas, IFN-beta, IFN-omega, IFN-kappa, and IFN-tau, are an evolutionarily conserved group of secreted cytokines that serve as potent extracellular mediators of host defense and homeostasis. Binding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d161af83d04503b42e949f9880083596
https://doi.org/10.1089/107999002760274845
https://doi.org/10.1089/107999002760274845
Publikováno v:
The Interferons: Characterization and Application
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::253a6813e2be5f31a322f5a025b44d5b
https://doi.org/10.1002/3527608206.ch7
https://doi.org/10.1002/3527608206.ch7
Autor:
Melissa M. Brierley, Eleanor N. Fish
Publikováno v:
Journal of interferoncytokine research : the official journal of the International Society for Interferon and Cytokine Research. 25(12)
The high-affinity binding interactions between interferons (IFNs) and their cognate cell surface receptors lead to the activation of receptor-associated Janus protein tyrosine kinases (Jaks) and subsequent phosphorylation and activation of a group of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94609a828829363954085111d6f35d5
https://pubmed.ncbi.nlm.nih.gov/16375601
https://pubmed.ncbi.nlm.nih.gov/16375601
Autor:
Eleanor N. Fish, Melissa M. Brierley
Publikováno v:
The Journal of biological chemistry. 280(13)
Several distinct type I interferon (IFN)-inducible STAT2-containing complexes have been identified. For the IFN-stimulated gene factor 3 (ISGF3), STAT1 and IRF-9 mediate IFN-stimulated response element (ISRE) binding, whereas STAT2 provides a potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a39847787cd92daa79192f3e3f069933
https://pubmed.ncbi.nlm.nih.gov/15668228
https://pubmed.ncbi.nlm.nih.gov/15668228