Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Melissa M. Alegre"'
Publikováno v:
Asian Pacific Journal of Cancer Prevention. 14:2207-2212
Cancer prevention is rapidly emerging as a major strategy to reduce cancer mortality. In the field of breast cancer, significant strides have recently been made in the understanding of underlying preventive mechanisms. Currently, three major strategi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e779bec3ec78a31732faddf29080e35
https://doi.org/10.7314/apjcp.2013.14.4.2207
https://doi.org/10.7314/apjcp.2013.14.4.2207
Autor:
Melissa M, Alegre, Michael J, Weyant, Daine T, Bennett, Jessica A, Yu, Madison K, Ramsden, Atif, Elnaggar, Richard A, Robison, Kim L, O'Neill
Publikováno v:
Anticancer research. 34(5)
Thymidine kinase 1 (TK1) is a biomarker elevated in several malignancies, including lung cancer. Up-regulation of TK1 is an early event in carcinogenesis and therefore a target for early cancer detection. We have developed a novel Enzyme Linked Immun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::22b1f38cd6a9700315692f4e20671a6e
https://pubmed.ncbi.nlm.nih.gov/24778016
https://pubmed.ncbi.nlm.nih.gov/24778016
Autor:
Michael Xiao, Atif M. El-Naggar, Philip M. Lynch, Kim L. O'Neill, Richard A. Robison, Melissa M. Alegre, Albert V. Helsing
Publikováno v:
Mutation research. Genetic toxicology and environmental mutagenesis. 771
Epidemiological studies have correlated exposure to ultraviolet-irradiated particulate matter with cardiovascular, respiratory, and lung diseases. This study investigated the DNA damage induced by two major inorganic particulate matter compounds foun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d89b5916cb7bf3fc910937a4abf9b9
https://pubmed.ncbi.nlm.nih.gov/25308436
https://pubmed.ncbi.nlm.nih.gov/25308436
Publikováno v:
Cancer and Clinical Oncology. 2
Thymidine Kinase 1 (TK1) is traditionally a serum biomarker which is elevated in the early stages of malignancies. TK1 is a DNA repair enzyme which is typically associated with proliferation. In serum, TK1 is elevated in a stage-like manner and incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::858907e6c6d98934908c3fdb62e91f56
https://doi.org/10.5539/cco.v2n1p159
https://doi.org/10.5539/cco.v2n1p159
Autor:
Daine T. Bennett, Jessica A. Yu, Melissa M. Alegre, Kim L. O'Neill, Madison K. Ramsden, Richard A. Robison, Michael J. Weyant, Atif Elnaggar
Publikováno v:
Cancer Research. 74:1866-1866
Lung cancer is the number one cause of cancer mortality and early detection will increase the survival of this disease. Thymidine kinase 1 (TK1) is a biomarker indicative of cell proliferation that is elevated in numerous malignancies including lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f22834d1037fb53b19276091c6a30e3
https://doi.org/10.1158/1538-7445.am2014-1866
https://doi.org/10.1158/1538-7445.am2014-1866
Autor:
Kim L. O'Neill, Michael Xiao, Richard A. Robison, Melissa M. Alegre, Philip M. Lynch, Atif M. El-Naggar, Albert V. Helsing
Publikováno v:
Cancer Research. 73:1790-1790
Epidemiological studies have correlated exposure to ultraviolet-irradiated particulate matter with cardiovascular, respiratory, and malignant lung diseases. This study investigated the DNA damage induced by two major inorganic particulate matter comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2a9ade9376d91d13506016883f1a354
https://doi.org/10.1158/1538-7445.am2013-1790
https://doi.org/10.1158/1538-7445.am2013-1790
Autor:
Joshua W. Foster, Daniel W. Sharp, Dagoberto Estevez, Brit L. Germann, Richard A. Robison, Kim L. O'Neill, Robert A. Whitehurst, Melissa M. Alegre
Publikováno v:
Cancer Research. 71:897-897
Thymidine Kinase 1 (TK1), an important nucleotide salvage pathway enzyme, has been shown to be upregulated in most malignant cancers. Recent studies have shown that TK1 not only has diagnostic and prognostic potential, but could also be used as a mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37f8de5cb6941aa7956fcbe263c66538
https://doi.org/10.1158/1538-7445.am2011-897
https://doi.org/10.1158/1538-7445.am2011-897
Autor:
Melissa M. Alegre, Robert A. Whitehurst, Kim L. O'Neill, Richard A. Robison, Daniel W. Sharp, Dagoberto Estevez
Publikováno v:
Cancer Research. 71:1678-1678
Thymidine Kinase 1(TK1) is a salvage pathway enzyme that has been shown to be elevated in many different cancer types, including breast, prostate, and colon. Previous research in our lab using plasma membrane separation has shown an increase in TK1 l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37921d53c2bf1fc674dd4f1080a93f5d
https://doi.org/10.1158/1538-7445.am2011-1678
https://doi.org/10.1158/1538-7445.am2011-1678
Autor:
Richard A. Robison, Wesley D. LaPorte, Taylor Abegg-Lawrence, Michael J. Weyant, Ballantines F. Alegre, Melissa M. Alegre, Kim L. O'Neill, Jessica A. Yu
Publikováno v:
Cancer Research. 71:3194-3194
Lung cancer kills more patients than breast, colon, prostate, melanoma, and kidney cancers combined. One way to improve the high lung cancer mortality rate is through early detection and better prognosis. There have been attempts to establish spiral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41fc910bdf14af8da40aa9d8d331d959
https://doi.org/10.1158/1538-7445.am2011-3194
https://doi.org/10.1158/1538-7445.am2011-3194
Publikováno v:
Cancer Research. 71:1511-1511
Macrophages are highly versatile phagocytes active in multiple roles in the immune system of vertebrates. However, within the tumor microenvironment, macrophages initiate and are exposed to a variety of cell signals. Some of these signals are involve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98e5a3cea6b65937ce8297555ac454a0
https://doi.org/10.1158/1538-7445.am2011-1511
https://doi.org/10.1158/1538-7445.am2011-1511