Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Melissa M Pentony"'
Autor:
Victor Moreno, Andrew Gerry, Tom Holdich, Anthony J Olszanski, Ramaswamy Govindan, John V Heymach, Matthew J Frigault, Siddhartha Devarakonda, Melissa Johnson, Justin Gainor, Carlos Bachier, Natalie Hyland, Jean-Marc Navenot, Svetlana Fayngerts, Jane Bai, Elliot Norry, Robyn Broad, George R Blumenschein, Martin J Edelman, Bernard Doger de Spéville, Vincent K Lam, Zohar Wolchinsky, Dzmitry Batrakou, Melissa M Pentony, Joseph P Sanderson, Diane Marks, Paula M Fracasso
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/bb48deb4a4b44ce99c7898cce61aa878
Autor:
Pamela J Kaisaki, Anthony Cutts, Niko Popitsch, Carme Camps, Melissa M Pentony, Gareth Wilson, Suzanne Page, Kulvinder Kaur, Dimitris Vavoulis, Shirley Henderson, Avinash Gupta, Mark R Middleton, Ioannis Karydis, Denis C Talbot, Anna Schuh, Jenny C Taylor
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162809 (2016)
Use of circulating tumour DNA (ctDNA) as a liquid biopsy has been proposed for potential identification and monitoring of solid tumours. We investigate a next-generation sequencing approach for mutation detection in ctDNA in two related studies using
Externí odkaz:
https://doaj.org/article/c84931d42bd34e6883e57ececea2c9cd
Autor:
Alistair T. Pagnamenta, Carme Camps, Edoardo Giacopuzzi, John M. Taylor, Mona Hashim, Eduardo Calpena, Pamela J. Kaisaki, Akiko Hashimoto, Jing Yu, Edward Sanders, Ron Schwessinger, Jim R. Hughes, Gerton Lunter, Helene Dreau, Matteo Ferla, Lukas Lange, Yesim Kesim, Vassilis Ragoussis, Dimitrios V. Vavoulis, Holger Allroggen, Olaf Ansorge, Christian Babbs, Siddharth Banka, Benito Baños-Piñero, David Beeson, Tal Ben-Ami, David L. Bennett, Celeste Bento, Edward Blair, Charlotte Brasch-Andersen, Katherine R. Bull, Holger Cario, Deirdre Cilliers, Valerio Conti, E. Graham Davies, Fatima Dhalla, Beatriz Diez Dacal, Yin Dong, James E. Dunford, Renzo Guerrini, Adrian L. Harris, Jane Hartley, Georg Hollander, Kassim Javaid, Maureen Kane, Deirdre Kelly, Dominic Kelly, Samantha J. L. Knight, Alexandra Y. Kreins, Erika M. Kvikstad, Craig B. Langman, Tracy Lester, Kate E. Lines, Simon R. Lord, Xin Lu, Sahar Mansour, Adnan Manzur, Reza Maroofian, Brian Marsden, Joanne Mason, Simon J. McGowan, Davide Mei, Hana Mlcochova, Yoshiko Murakami, Andrea H. Németh, Steven Okoli, Elizabeth Ormondroyd, Lilian Bomme Ousager, Jacqueline Palace, Smita Y. Patel, Melissa M. Pentony, Chris Pugh, Aboulfazl Rad, Archana Ramesh, Simone G. Riva, Irene Roberts, Noémi Roy, Outi Salminen, Kyleen D. Schilling, Caroline Scott, Arjune Sen, Conrad Smith, Mark Stevenson, Rajesh V. Thakker, Stephen R. F. Twigg, Holm H. Uhlig, Richard van Wijk, Barbara Vona, Steven Wall, Jing Wang, Hugh Watkins, Jaroslav Zak, Anna H. Schuh, Usha Kini, Andrew O. M. Wilkie, Niko Popitsch, Jenny C. Taylor
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-25 (2023)
Abstract Background Whole genome sequencing is increasingly being used for the diagnosis of patients with rare diseases. However, the diagnostic yields of many studies, particularly those conducted in a healthcare setting, are often disappointingly l
Externí odkaz:
https://doaj.org/article/c9f00f4d0c70402d8c69f3f7e4981fbc
Autor:
George R Blumenschein, Siddhartha Devarakonda, Melissa Johnson, Victor Moreno, Justin Gainor, Martin J Edelman, John V Heymach, Ramaswamy Govindan, Carlos Bachier, Bernard Doger de Spéville, Matthew J Frigault, Anthony J Olszanski, Vincent K Lam, Natalie Hyland, Jean-Marc Navenot, Svetlana Fayngerts, Zohar Wolchinsky, Robyn Broad, Dzmitry Batrakou, Melissa M Pentony, Joseph P Sanderson, Andrew Gerry, Diane Marks, Jane Bai, Tom Holdich, Elliot Norry, Paula M Fracasso
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
BackgroundADP-A2M10 specific peptide enhanced affinity receptor (SPEAR) T cells (ADP-A2M10) are genetically engineered autologous T cells that express a high-affinity melanoma-associated antigen A10 (MAGE-A10)-specific T-cell receptor (TCR) targeting
Autor:
Melissa M. Pentony, Sanjay M. Sisodiya, Martin Armstrong, Alistair T. Pagnamenta, Samantha J. L. Knight, Jenny C. Taylor, Dimitrios V Vavoulis, Simona Balestrini, Elizabeth Caruana Galizia
In the context of pharmacogenomics, whole genome sequencing provides a powerful approach for identifying correlations between response variability to specific drugs and genomic polymorphisms in a population, in an unbiased manner. In this study, we e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ff93f38a28d3c702da708594c9e1a7
http://arxiv.org/abs/1909.10580
http://arxiv.org/abs/1909.10580
Autor:
Adrian M. Shields, Alistair T. Pagnamenta, Andrew J. Pollard, OxClinWGS, Jenny C. Taylor, Holger Allroggen, Smita Y. Patel, Samantha J. L. Knight, Niko Popitsch, Carme Camps, Melissa M. Pentony, Erika M. Kvikstad, Lukas Lange, Mona Hashim, Steve Harris, Mark Tilley, Dimitris Vavoulis, Pamela Kaisaki, Vassilis Ragoussis, Matteo Feral
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Deficiency of complement factor I is a rare immunodeficiency that typically presents with increased susceptibility to encapsulated bacterial infections. However, non-infectious presentations including rheumatological, dermatological and neurological
Autor:
Mathias Vilaine, Céline Garrec, Pierre Lindenbaum, Sophie Couvé, Mathilde Pacault, Laurence Heidet, Stéphane Bézieau, Celeste Bento, David Hoogewijs, Helene Dreau, Yannick Arlot-Bonnemains, Nelly Burnichon, Marion Lenglet, Richard van Wijk, Maria-Luigia Randi, Alexandre Buffet, Florence Robriquet, Fabrice Airaud, Holger Cario, Nicolas Janin, Melissa M. Pentony, Erika Kvikstad, Stéphane Richard, Karim Bouchireb, Antonis Kattamis, Jean-Michaël Mazzella, Carme Camps, Sylvie Job, Sophie Ferlicot, Anne Couturier, Richard Redon, Maria Caterina Putti, Thomas Besnard, Joachim R. Göthert, Klaus-Michael Debatin, Betty Gardie, Sophie Deveaux, Franck Chesnel, Solenne Dumont, Jenny C. Taylor, Marine Cornec, Bin Tean Teh, François Girodon, Vincent Bours, Sophie Gad, Anne-Paule Gimenez-Roqueplo, Sabine Irtan, Klaus Schwarz, Elpis Mantadakis, Samantha J. L. Knight, Brigitte Bressac-de Paillerets
Publikováno v:
Blood
Blood, 2018, 132 (5), pp.469-483. ⟨10.1182/blood-2018-03-838235⟩
Blood, American Society of Hematology, 2018, 132 (5), pp.469-483. ⟨10.1182/blood-2018-03-838235⟩
Blood, Vol. 132, no.5, p. 469-483 (2018)
Blood, 2018, 132 (5), pp.469-483. ⟨10.1182/blood-2018-03-838235⟩
Blood, American Society of Hematology, 2018, 132 (5), pp.469-483. ⟨10.1182/blood-2018-03-838235⟩
Blood, Vol. 132, no.5, p. 469-483 (2018)
International audience; Chuvash polycythemia is an autosomal recessive form of erythrocytosis associated with a homozygous p.Arg200Trp mutation in the von Hippel-Lindau (VHL) gene. Since this discovery, additional VHL mutations have been identified i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0880746e10359614471af0a533de25b
https://hal.science/hal-01833917
https://hal.science/hal-01833917
Autor:
Joe Harvey, Matteo P. Ferla, Ricky A. Sharma, Jenny C. Taylor, E Giacopuzzi, Pamela J. Kaisaki, McCullagh Jso., H Winter, Melissa M. Pentony, Knight Sjl.
Publikováno v:
Cancers
Volume 11
Issue 12
Volume 11
Issue 12
Intrahepatic cholangiocarcinoma (ICC) is an aggressive cancer arising from the bile ducts with a need for earlier diagnosis and a greater range of treatment options. KRAS/NRAS mutations are common in ICC tumours and 6&ndash
32% of patients also
32% of patients also
Autor:
Nicholas A. Athanasou, Stuart Winter, Richard Colling, Jenny C. Taylor, Kate Ridout, Adrian L. Harris, Erika Kvikstad, Andrew Protheroe, Angela Hamblin, David N. Church, Zsolt Orosz, Anna Schuh, Knight Sjl., Adrienne M. Flanagan, Ketan A. Shah, Niko Popitsch, T Mizani, B. Hassan, Helene Dreau, Melissa M. Pentony, Ahmed Ashour Ahmed, M Parton, Pavlos Antoniou, Dimitris Vavoulis, Ian Tomlinson
Publikováno v:
Cold Spring Harbor Molecular Case Studies
Schuh, A, Dreau, H, Knight, S J L, Ridout, K, Mizani, T, Vavoulis, D, Colling, R, Antoniou, P, Kvikstad, E M, Pentony, M M, Hamblin, A, Protheroe, A, Parton, M, Shah, K A, Orosz, Z, Athanasou, N, Hassan, B, Flanagan, A M, Ahmed, A, Winter, S, Harris, A, Tomlinson, I, Popitsch, N, Church, D & Taylor, J C 2018, ' Clinically actionable mutation profiles in patients with cancer identified by whole-genome sequencing ', Molecular Case Studies, vol. 4, no. 2, pp. a002279 . https://doi.org/10.1101/mcs.a002279
Schuh, A, Dreau, H, Knight, S J L, Ridout, K, Mizani, T, Vavoulis, D, Colling, R, Antoniou, P, Kvikstad, E M, Pentony, M M, Hamblin, A, Protheroe, A, Parton, M, Shah, K A, Orosz, Z, Athanasou, N, Hassan, B, Flanagan, A M, Ahmed, A, Winter, S, Harris, A, Tomlinson, I, Popitsch, N, Church, D & Taylor, J C 2018, ' Clinically actionable mutation profiles in patients with cancer identified by whole-genome sequencing ', Molecular Case Studies, vol. 4, no. 2, pp. a002279 . https://doi.org/10.1101/mcs.a002279
Next-generation sequencing (NGS) efforts have established catalogs of mutations relevant to cancer development. However, the clinical utility of this information remains largely unexplored. Here, we present the results of the first eight patients rec
Autor:
Melissa M. Pentony, David T. Jones
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 78:212-221
Predicting regions of disorder has become of increasing interest when determining protein structure and function. With approximately 33% of eukaryotic proteins having significant disordered regions, and an increasing occurrence of disorder in higher