Clinical Validation of a Multi-Biomarker Assay for the Evaluation of Chronic Pain Patients in a Cross-Sectional, Observational Study

Autor: Kasra Amirdelfan, Jason E. Pope, Joshua Gunn, Melissa M. Hill, Bradley M. Cotten, John E. Beresh, Douglas Dobecki, Nathan Miller, Pankaj Mehta, George Girardi, Timothy R. Deer

Publikováno v: Pain and Therapy, Vol 9, Iss 2, Pp 511-529 (2020)

Abstract Introduction Chronic pain assessment and post-treatment evaluation continues to be challenging due to a lack of validated, objective tools to measure patient outcomes. Validation of mechanistic pain biomarkers would allow clinicians to objec

Externí odkaz: https://doaj.org/article/b568bd7d8c724217b411d2c6ec81c019

Cross-Validation of the Foundation Pain Index with PROMIS-29 in Chronic Pain Patients

Autor: Michael A Fishman, Melissa M Hill, Joshua A. Gunn, Bradley M Cotten, Jason E. Pope, Timothy R. Deer

Publikováno v: Journal of Pain Research

Jason E Pope,1 Michael A Fishman,2 Joshua A Gunn,3 Bradley M Cotten,3 Melissa M Hill,3 Timothy R Deer4 1Evolve Restorative Center, Santa Rosa, CA, USA; 2Center for Interventional Pain and Spine, Lancaster, PA, USA; 3Ethos Research and Development, LL

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff9d84b6ec884a412d3ef57e6e6512c
https://doi.org/10.2147/jpr.s314021

An Analysis of Biomarkers in Patients with Chronic Pain

Autor: Timothy R. Deer, Melissa M Hill, Bradley M Cotten, Joshua A. Gunn

Publikováno v: Pain Physician. :E41-E49

Background: Because of the subjective nature of current pain assessments, limited efficacy of treatment options and risks associated with opioid abuse and diversion, the need for objective data to assist with chronic pain management has never been gr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c7f8c283dccfab5a7f5d129e14a2a811
https://doi.org/10.36076/ppj.2020/23/e41

Association of urinary concentrations of phthalate metabolites with quinolinic acid among women: a potential link to neurological disorders

Autor: Joshua A. Gunn, Paige L. Williams, Feiby L. Nassan, Melissa M Hill, Russ Hauser

Publikováno v: Environ Int
Environment International, Vol 138, Iss, Pp-(2020)

Background: Quinolinic acid (QA), a neuroactive metabolite produced during tryptophan degradation, is implicated in the pathogenesis of several neurological disorders. Phthalates are structurally similar to QA, and exposure to phthalates has demonstr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20647d64a8416e5071adea82d6e607e0
https://europepmc.org/articles/PMC7136979/

Implementation of a National Prenatal Exome Sequencing Service in England: Cost-Effectiveness Analysis.

Autor: Smith EJ; NHS North Thames Genomic Laboratory Hub, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK., Hill M; NHS North Thames Genomic Laboratory Hub, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.; Genetics and Genomic Medicine, UCL Great Ormond Street Institute of Child Health, London, UK., Peter M; NHS North Thames Genomic Laboratory Hub, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.; Genetics and Genomic Medicine, UCL Great Ormond Street Institute of Child Health, London, UK., Wu WH; NHS North Thames Genomic Laboratory Hub, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.; Genetics and Genomic Medicine, UCL Great Ormond Street Institute of Child Health, London, UK., Mallinson C; National Disease Registration Service, National Health Service England, London, UK., Hardy S; National Disease Registration Service, National Health Service England, London, UK., Chitty LS; NHS North Thames Genomic Laboratory Hub, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.; Genetics and Genomic Medicine, UCL Great Ormond Street Institute of Child Health, London, UK., Morris S; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

Publikováno v: BJOG : an international journal of obstetrics and gynaecology [BJOG] 2024 Nov 21. Date of Electronic Publication: 2024 Nov 21.