Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Melissa Lever"'
Autor:
André N. A. Gonçalves, Melissa Lever, Pedro S. T. Russo, Bruno Gomes-Correia, Alysson H. Urbanski, Gabriele Pollara, Mahdad Noursadeghi, Vinicius Maracaja-Coutinho, Helder I. Nakaya
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Transcriptome analyses have increased our understanding of the molecular mechanisms underlying human diseases. Most approaches aim to identify significant genes by comparing their expression values between healthy subjects and a group of patients wit
Externí odkaz:
https://doaj.org/article/a1aeaa364c774bee95cc4aebf392b5d8
Autor:
Pedro S. T. Russo, Gustavo R. Ferreira, Lucas E. Cardozo, Matheus C. Bürger, Raul Arias-Carrasco, Sandra R. Maruyama, Thiago D. C. Hirata, Diógenes S. Lima, Fernando M. Passos, Kiyoshi F. Fukutani, Melissa Lever, João S. Silva, Vinicius Maracaja-Coutinho, Helder I. Nakaya
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-13 (2018)
Abstract Background The analysis of modular gene co-expression networks is a well-established method commonly used for discovering the systems-level functionality of genes. In addition, these studies provide a basis for the discovery of clinically re
Externí odkaz:
https://doaj.org/article/94a2b03cc29e422688eda0c781db2dd2
Autor:
Matheus Carvalho Bürger, João Santana da Silva, Thiago Dominguez Crespo Hirata, Kiyoshi F. Fukutani, Raúl Arias-Carrasco, Lucas Esteves Cardozo, Pedro de Sá Tavares Russo, Vinicius Maracaja-Coutinho, Helder I. Nakaya, Sandra Regina Maruyama, Fernando M. Passos, Gustavo Rodrigues Ferreira, Melissa Lever, Diógenes S. de Lima
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-13 (2018)
BMC Bioinformatics
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
BMC Bioinformatics
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Background The analysis of modular gene co-expression networks is a well-established method commonly used for discovering the systems-level functionality of genes. In addition, these studies provide a basis for the discovery of clinically relevant mo
Autor:
Jillian L. Goldfarb, Alexander Billias, Melissa Lever, Erica Gunn, Esteve N. Casoliba, Andrea Schievano, Fabrizio Adani, Li Buessing
Publikováno v:
ACS Sustainable Chemistry & Engineering. 5:876-884
Olive mill waste (OMW) management has been a problem in the Mediterranean basin for thousands of years. The solid exiting the extraction process contains polyphenols that are beneficial to humans and phytotoxic to plants. We propose an integrated bio
Publikováno v:
Theoretical and Applied Aspects of Systems Biology ISBN: 9783319749730
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e05a61c1d270d2d5c1119865a77a11d5
https://doi.org/10.1007/978-3-319-74974-7_9
https://doi.org/10.1007/978-3-319-74974-7_9
Autor:
David M. Kranz, Philipp Kruger, Marlies V. Hager, Omer Dushek, Philip D. Greenberg, Melissa Lever, Jennifer D. Stone, Daniel T. Harris, Sheena N. Smith, Qi Cai, Thomas M. Schmitt
Publikováno v:
Journal of Immunology. 200(3)
Adoptive T cell therapies have achieved significant clinical responses, especially in hematopoietic cancers. Two types of receptor systems have been used to redirect the activity of T cells, normal heterodimeric TCRs or synthetic chimeric Ag receptor
Publikováno v:
Scopus-Elsevier
Current Issues in Molecular Biology
Volume 21
Issue 1
Pages 1-16
Current Issues in Molecular Biology
Volume 21
Issue 1
Pages 1-16
DNA vaccination represents a new milestone in our technological efforts to avoid infectious diseases. Although this method of vaccination has had success in providing protection in animals, these vaccines suffer from low immunogenicity in humans. Que
Autor:
Philipp Kruger, Omer Dushek, Hong-Sheng Lim, Enas Abu-Shah, Nicola Trendel, Philip K. Maini, Melissa Lever, John Nguyen, Philip Anton van der Merwe
T cells must respond differently to antigens of varying affinity presented at different doses. Previous attempts to map peptide MHC (pMHC) affinity onto T-cell responses have produced inconsistent patterns of responses, preventing formulations of can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f546629fdb8d570659238abb7aa12bb
https://ora.ox.ac.uk/objects/uuid:729d5f39-1e9b-4a73-8b7a-27cf81faed25
https://ora.ox.ac.uk/objects/uuid:729d5f39-1e9b-4a73-8b7a-27cf81faed25
Autor:
Omer Dushek, Philipp Kruger, Enas Abu-Shah, Hong-Sheng Lim, Philip K. Maini, Nicola Trendel, John Nguyen, Melissa Lever, Philip Anton van der Merwe
T cells must respond differently to antigens of varying affinity presented at different doses. Previous attempts to map pMHC affinity onto T cell responses have produced inconsistent patterns of responses preventing formulations of canonical models o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e38ab968f9491618a8967de2878b5e0b
Autor:
Peter Jönsson, J Southcombe, Xiao-Ning Xu, Omer Dushek, Andrew James Godkin, Simon J. Davis, David Klenerman, Jamie Rossjohn, Paul Dunne, Jan Petersen, Edward J. Evans, Melissa Lever, Alexander Hudson, Lars Fugger, Ana Filipa L.O.M. Santos, Matthieu Palayret, James McColl, Gavin R. Screaton, Mathew H. Horrocks, Ricardo A. Fernandes, Tomáš Hanke, Jiandong Huo, Veronica T. Chang
Publikováno v:
Jönsson, P, Southcombe, J H, Santos, A M, Huo, J, Fernandes, R A, McColl, J, Lever, M, Evans, E J, Hudson, A, Chang, V T, Hanke, T, Godkin, A, Dunne, P D, Horrocks, M H, Palayret, M, Screaton, G R, Petersen, J, Rossjohn, J, Fugger, L, Dushek, O, Xu, X-N, Davis, S J & Klenerman, D 2016, ' Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions ', Proceedings of the National Academy of Sciences of the United States of America, vol. 113, no. 20, pp. 5682-7 . https://doi.org/10.1073/pnas.1513918113
The αβ T-cell coreceptor CD4 enhances immune responses more than 1 million-fold in some assays, and yet the affinity of CD4 for its ligand, peptide-major histocompatibility class II (pMHC II) on antigen-presenting cells, is so weak that it was prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fc1ff456905f6d9c6ee2d495cb3b008