Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Melissa L. Sinkus"'
Autor:
Robert Freedman, Melissa L. Sinkus, Sherry Leonard, Sharon L. Graw, Henry A. Lester, Randal G. Ross
Publikováno v:
Neuropharmacology. 96:274-288
The human α7 neuronal nicotinic acetylcholine receptor gene (CHRNA7) is ubiquitously expressed in both the central nervous system and in the periphery. CHRNA7 is genetically linked to multiple disorders with cognitive deficits, including schizophren
Publikováno v:
Brain, Behavior, and Immunity. 32:51-62
Schizophrenia is a common mental illness with a large genetic component. Three genome-wide association studies have implicated the major histocompatibility complex gene region on chromosome 6p21.3-22.1 in schizophrenia. In addition, nicotine, which i
Autor:
Tasha E. Fingerlin, Melissa L. Sinkus, Mark L. Laudenslager, Amanda Barton, Marianne Z. Wamboldt, Sherry Leonard
Publikováno v:
Physiologybehavior. 104(2)
α7 Nicotinic acetylcholine receptors (α7nAchRs) modulate immune activation by suppressing production of pro-inflammatory cytokines in peripheral immune cells. α7nAchRs also modulate inhibitory output in the hippocampus, which provides input to key
Autor:
Robert Freedman, Judith Logel, Judith Gault, Sherry Leonard, Susan L. Christian, Melissa L. Sinkus, Jennifer Lyon, Michael J. Lee, Margaret Short
Publikováno v:
Brain research. 1291
Multiple genetic linkage studies support the hypothesis that the 15q13–14 chromosomal region contributes to the etiology of schizophrenia. Among the putative candidate genes in this area are the α7 nicotinic acetylcholine receptor gene (CHRNA7) an
Publikováno v:
Schizophrenia Research. 136:S74-S75
Publikováno v:
Biochemical Pharmacology. 82:1046-1047
Autor:
Melissa L. Sinkus, Sherry Leonard, Tasha E. Fingerlin, Amanda Barton, Mark L. Laudenslager, Marianne Z. Wamboldt
Publikováno v:
Brain, Behavior, and Immunity. 23:S56