Výsledky vyhledávání - "Melissa L. Nguyen"

Akademický článek

MHC Class II and Non-MHC Class II Genes Differentially Influence Humoral Immunity to Bacillus anthracis Lethal Factor and Protective Antigen

Autor: Judith A. James, A. Darise Farris, Melissa L. Nguyen, Philip M. Cox, Sherry R. Crowe, Eric K. Dumas, Sridevi Kurella, Jonathan J. Hunt, Lori Garman

Publikováno v: Toxins, Vol 4, Iss 12, Pp 1451-1467 (2012)

Anthrax Lethal Toxin consists of Protective Antigen (PA) and Lethal Factor (LF), and current vaccination strategies focus on eliciting antibodies to PA. In human vaccination, the response to PA can vary greatly, and the response is often directed tow

Externí odkaz: https://doaj.org/article/4e1fcabc602e409b9a1e6fb335510e5a

Zobrazit plný text záznamu

Candidacidal activity of synthetic peptides based on the antimicrobial domain of the neutrophil-derived protein, CAP37

Autor: Melissa L. Nguyen, Thuy-Trang Nguyen, Heather Hinsley, H. Anne Pereira, Irina Tsyshevskaya-Hoover, Jan Pohl, Sreemathi Logan, Paul L. Fidel, Karen L. Wozniak

Publikováno v: Medical Mycology. 48:263-272

The primary bactericidal domain of CAP37, a cationic antimicrobial protein with potent activity against Gram-negative organisms was previously shown to reside between amino acids 20 through 44 (NQGRHFCGGALIHARFVMTAASCFQ) of the native protein. In thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d079b5f6c8c9144c99c2291bb4020b85
https://doi.org/10.3109/13693780903081976

Zobrazit plný text záznamu

Sequential B-Cell Epitopes ofBacillus anthracisLethal Factor Bind Lethal Toxin-Neutralizing Antibodies

Autor: A. Darise Farris, Jimmy D. Ballard, Judith A. James, Sherry R. Crowe, Simon Teryzan, Melissa L. Nguyen, Brian Cao, Sridevi Kurella

Publikováno v: Infection and Immunity. 77:162-169

The bipartite anthrax lethal toxin (LeTx) consisting of protective antigen (PA) and lethal factor (LF) is a major virulence factor contributing to death from systemicBacillus anthracisinfection. The current vaccine elicits antibodies directed primari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5b2e8a97dcf2656920ea5969008a448
https://doi.org/10.1128/iai.00788-08

Zobrazit plný text záznamu

Stochastic humoral immunity to Bacillus anthracis Protective Antigen: Identification of anti-peptide IgG correlating with seroconversion to Lethal Toxin neutralization

Autor: Melissa L. Nguyen, Philip M. Cox, Judith A. James, A. Darise Farris, Heidi Rodgers, Eric K. Dumas, Joanne L. Peterson

A substantial fraction of individuals vaccinated against anthrax have low to immeasurable levels of serum Lethal Toxin (LeTx)-neutralizing activity. The only known correlate of protection against Bacillus anthracis in the currently licensed vaccine i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0244de643eaff77f38aad9878e6b14b
https://europepmc.org/articles/PMC3614092/

Zobrazit plný text záznamu

MHC class II and non-MHC class II genes differentially influence humoral immunity to Bacillus anthracis lethal factor and protective antigen

Autor: Sridevi Kurella, Eric K. Dumas, Lori Garman, Melissa L. Nguyen, Jonathan J. Hunt, Sherry R. Crowe, Philip M. Cox, Judith A. James, A. Darise Farris

Publikováno v: Toxins
Toxins; Volume 4; Issue 12; Pages: 1451-1467
Toxins, Vol 4, Iss 12, Pp 1451-1467 (2012)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d0356d737db219aea50769b92be57eb
https://pubmed.ncbi.nlm.nih.gov/23342680

Zobrazit plný text záznamu

Anthrax lethal toxin-induced gene expression changes in mouse lung

Autor: Eric K. Dumas, Mark Barton Frank, Philip M. Cox, Melissa L. Nguyen, Charles O Connor Fullenwider, Michael Centola, Judith A. James, A. Darise Farris, Igor Dozmorov

Publikováno v: Toxins
Volume 3
Issue 9
Pages 1111-1130
Toxins, Vol 3, Iss 9, Pp 1111-1130 (2011)

A major virulence factor of Bacillus anthracis is the anthrax Lethal Toxin (LeTx), a bipartite toxin composed of Protective Antigen and Lethal Factor. Systemic administration of LeTx to laboratory animals leads to death associated with vascular leaka

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::182c2f3bb949a794932c53d421718941
https://pubmed.ncbi.nlm.nih.gov/22039574

Zobrazit plný text záznamu

The major neutralizing antibody responses to recombinant anthrax lethal and edema factors are directed to non-cross-reactive epitopes

Autor: Jimmy D. Ballard, Simon Terzyan, Judith A. James, Melissa L. Nguyen, A. Darise Farris

Publikováno v: Infection and immunity. 77(11)

Anthrax lethal and edema toxins (LeTx and EdTx, respectively) form by binding of lethal factor (LF) or edema factor (EF) to the pore-forming moiety protective antigen (PA). Immunity to LF and EF protects animals from anthrax spore challenge and neutr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec7747384e7523d59125fe8836566976
https://pubmed.ncbi.nlm.nih.gov/19720758

Zobrazit plný text záznamu

Cross-reactive humoral epitopes of EF and LF are identified but do not constitute major anthrax toxin neutralization responses following EF and LF vaccination (132.20)

Autor: Melissa L Nguyen, Jimmy D Ballard, Judith A James, Darise Farris

Publikováno v: The Journal of Immunology. 182:132.20-132.20

BACKGROUND: Anthrax Lethal and Edema Toxins (LTx and ETx) are formed by binding of Lethal Factor (LF) or Edema Factor (EF) to the pore-forming moiety, Protective Antigen (PA). Immunity to LF and EF neutralize anthrax toxins. AIM: LF and EF immune ser

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::39b58332b3ec85a35a665a63ff99de4d
https://doi.org/10.4049/jimmunol.182.supp.132.20

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání