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pro vyhledávání: '"Melissa L. Fowler"'
Autor:
Brandon Tavshanjian, Jacob A. McPhail, Khanh Nguyen, Anming Xiong, Michael A. Gelman, Jeffrey S. Glenn, Melissa L. Fowler, Gillian L. Dornan, Kevan M. Shokat, Florentine U. Rutaganira, John E. Burke
Publikováno v:
Journal of Medicinal Chemistry. 59:1830-1839
Type III Phosphatidylinositol 4-kinase (PI4KIIIβ) is an essential enzyme in mediating membrane trafficking, and is implicated in a variety of pathogenic processes. It is a key host factor mediating replication of RNA viruses. The design of potent an
Autor:
Melissa L, Fowler, Jacob A, McPhail, Meredith L, Jenkins, Glenn R, Masson, Florentine U, Rutaganira, Kevan M, Shokat, Roger L, Williams, John E, Burke
Publikováno v:
Protein Science : A Publication of the Protein Society
The ability of proteins to bind and interact with protein partners plays fundamental roles in many cellular contexts. X‐ray crystallography has been a powerful approach to understand protein‐protein interactions; however, a challenge in the cryst