Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Melissa L. Erickson‐Beltran"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Prions propagate by a template driven process, inducing the normal cellular isoform (PrPC) to adopt the prion (PrPSc) conformation. In PrPC, the positions of lysines are highly conserved and strongly influence prion propagation. In this study, covale
Externí odkaz:
https://doaj.org/article/bb6b0029a31f472f955ab412db7b6b98
Autor:
Christopher J. Silva, Melissa L. Erickson-Beltran, Craig B. Skinner, Stephanie A. Patfield, Xiaohua He
Publikováno v:
Toxins, Vol 7, Iss 12, Pp 5236-5253 (2015)
Shiga-like toxins (verotoxins) are responsible for the virulence associated with a variety of foodborne bacterial pathogens. Direct detection of toxins requires a specific and sensitive technique. In this study, we describe a mass spectrometry-based
Externí odkaz:
https://doaj.org/article/ed5713fedb3f4d3bbb21726612a0d58d
Autor:
Nathan Diplock, Maël Baudin, Leslie Harden, Christopher J. Silva, Melissa L. Erickson‐Beltran, Jana A. Hassan, Jennifer D. Lewis
Publikováno v:
Plant, Cell & Environment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a2101fa1fec8dbfe98425d164c292d5
https://doi.org/10.1111/pce.14603
https://doi.org/10.1111/pce.14603
Autor:
Christopher J. Silva, Eric D. Cassmann, Justin J. Greenlee, Melissa L. Erickson-Beltran, Jésus R. Requena
Publikováno v:
Journal of the American Society for Mass Spectrometry.
In sheep, the transmissibility and progression of scrapie, a sheep prion (PrP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d2fb4205943386bca250b0d0c27800
https://pubmed.ncbi.nlm.nih.gov/36622794
https://pubmed.ncbi.nlm.nih.gov/36622794
Autor:
Irina Dynin, Bruce Onisko, Jesús R. Requena, Melissa L. Erickson-Beltran, Christopher J. Silva
Publikováno v:
Journal of Agricultural and Food Chemistry. 69:2279-2286
Prions cause transmissible and inevitably fatal neurological diseases in agriculturally important animals, including bovine spongiform encephalopathy in domestic cattle, scrapie in sheep and goats, and chronic wasting disease in cervids. Because anim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d76871addb1317f9a11a078ffc80c6b
https://doi.org/10.1021/acs.jafc.0c06241
https://doi.org/10.1021/acs.jafc.0c06241
Autor:
Christopher J. Silva, Melissa L. Erickson-Beltran, Debbie McKenzie, Judd M. Aiken, Camilo Duque Velásquez
Publikováno v:
Analytical chemistry. 92(1)
Chronic wasting disease (CWD) is the only prion disease naturally transmitted among farmed and free-ranging cervids (deer, elk, moose, etc.). These diseases are always fatal and have long asymptomatic incubation periods. By 2019, CWD-infected cervids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b54cd099b26a3ce3859a8fbb73f40b
https://pubmed.ncbi.nlm.nih.gov/31815434
https://pubmed.ncbi.nlm.nih.gov/31815434
Autor:
Rosa Bolea, Juan José Badiola, Jesús R. Requena, Inmaculada Martín-Burriel, Melissa L. Erickson-Beltran, Christopher J. Silva
Publikováno v:
Analytical Chemistry. 90:1255-1262
Atypical scrapie is a sheep prion (PrPSc) disease whose epidemiology is consistent with a sporadic origin and is associated with specific polymorphisms of the normal cellular prion protein (PrPC). To determine the relative amounts of PrP polymorphism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f034400b86b36fd2f3e561c04198815
https://doi.org/10.1021/acs.analchem.7b03985
https://doi.org/10.1021/acs.analchem.7b03985
Autor:
Jesús R. Requena, Juan José Badiola, Melissa L. Erickson-Beltran, Rosa Bolea, Christopher J. Silva, Eric M. Nicholson, Colleen Hui
Publikováno v:
Analytical Chemistry. 89:854-861
Scrapie is a prion (PrPSc) disease of sheep. The incubation period of sheep scrapie is strongly influenced by polymorphisms at positions 136, 154, and 171 of a sheep’s normal cellular prion protein (PrPC). Chymotrypsin was used to digest sheep reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7515eb9002d770550fe5e849845327ee
https://doi.org/10.1021/acs.analchem.6b03822
https://doi.org/10.1021/acs.analchem.6b03822
Publikováno v:
Biochemistry. 55:894-902
Prions (PrP(Sc)) are molecular pathogens that are able to convert the isosequential normal cellular prion protein (PrP(C)) into a prion. The only demonstrated difference between PrP(C) and PrP(Sc) is conformational: they are isoforms. A given host ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd37ac62dba4cd250427fe41e004398
https://doi.org/10.1021/acs.biochem.5b01068
https://doi.org/10.1021/acs.biochem.5b01068
Autor:
Craig Skinner, Stephanie Patfield, Christopher J. Silva, Xiaohua He, Melissa L. Erickson-Beltran
Publikováno v:
Toxins, Vol 7, Iss 12, Pp 5236-5253 (2015)
Toxins; Volume 7; Issue 12; Pages: 5236-5253
Toxins
Volume 7
Issue 12
Pages 5236-5253
Toxins; Volume 7; Issue 12; Pages: 5236-5253
Toxins
Volume 7
Issue 12
Pages 5236-5253
Shiga-like toxins (verotoxins) are responsible for the virulence associated with a variety of foodborne bacterial pathogens. Direct detection of toxins requires a specific and sensitive technique. In this study, we describe a mass spectrometry-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e6bef08404f18c41754a2dbc6a20f76
https://doi.org/10.3390/toxins7124875
https://doi.org/10.3390/toxins7124875