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pro vyhledávání: '"Melissa L. D. Rayner"'
Autor:
Melissa L. D. Rayner, Simon C. Kellaway, Isabel Kingston, Owein Guillemot-Legris, Holly Gregory, Jess Healy, James B. Phillips
Publikováno v:
Cells, Vol 12, Iss 1, p 42 (2022)
Damage to peripheral nerves can cause debilitating consequences for patients such as lifelong pain and disability. At present, no drug treatments are routinely given in the clinic following a peripheral nerve injury (PNI) to improve regeneration and
Externí odkaz:
https://doaj.org/article/1f53a5f6c7aa4736a2fb0b9b688ade79
Publikováno v:
Biomolecules, Vol 11, Iss 9, p 1301 (2021)
The slow rate of neuronal regeneration that follows peripheral nerve repair results in poor recovery, particularly where reinnervation of muscles is delayed, leading to atrophy and permanent loss of function. There is a clear clinical need to develop
Externí odkaz:
https://doaj.org/article/30185c33b4ae4c0d81c27c1e7dcf6e95
Autor:
Savroop Bhamra, Parineeta Arora, Szymon W. Manka, Christian Schmidt, Craig Brown, Melissa L. D. Rayner, Peter-Christian Klöhn, Anthony R. Clarke, John Collinge, Parmjit S. Jat
Prions consist of assemblies of aberrantly folded cellular prion protein (PrPC) upon template-assisted conversion and propagation of disease-associated PrP. To dissect the N-terminal residues critical for efficient prion propagation, we generated a l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13379c73087367c006d43d47569dab4a
https://doi.org/10.1101/2022.08.08.503133
https://doi.org/10.1101/2022.08.08.503133
Publikováno v:
Biomolecules
Biomolecules, Vol 11, Iss 1301, p 1301 (2021)
Biomolecules, Vol 11, Iss 1301, p 1301 (2021)
The slow rate of neuronal regeneration that follows peripheral nerve repair results in poor recovery, particularly where reinnervation of muscles is delayed, leading to atrophy and permanent loss of function. There is a clear clinical need to develop
Publikováno v:
Acta biomaterialia. 135
A surgical autograft remains the clinical gold-standard therapy for gap repair following peripheral nerve injury, however, challenges remain with achieving full recovery and reducing donor-site morbidity. Engineered Neural Tissue (EngNT) manufactured
Publikováno v:
Peripheral Nerve Tissue Engineering and Regeneration ISBN: 9783030062170
Peripheral Nerve Tissue Engineering and Regeneration
Peripheral Nerve Tissue Engineering and Regeneration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3746319420c6c300a86be7bc94aec962
https://doi.org/10.1007/978-3-030-06217-0_16-1
https://doi.org/10.1007/978-3-030-06217-0_16-1
Autor:
Melissa L D, Rayner, Simão, Laranjeira, Rachael E, Evans, Rebecca J, Shipley, Jess, Healy, James B, Phillips
Publikováno v:
Anatomical Record (Hoboken, N.j. : 2007)
Peripheral nerve injuries (PNI) have a high prevalence and can be debilitating, resulting in life‐long loss or disturbance in end‐organ function, which compromises quality of life for patients. Current therapies use microsurgical approaches but t