Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Melissa L. Conerly"'
Autor:
Sean C Shadle, Jun Wen Zhong, Amy E Campbell, Melissa L Conerly, Sujatha Jagannathan, Chao-Jen Wong, Timothy D Morello, Silvère M van der Maarel, Stephen J Tapscott
Publikováno v:
PLoS Genetics, Vol 13, Iss 3, p e1006658 (2017)
Facioscapulohumeral dystrophy (FSHD) is caused by the mis-expression of DUX4 in skeletal muscle cells. DUX4 is a transcription factor that activates genes normally associated with stem cell biology and its mis-expression in FSHD cells results in apop
Externí odkaz:
https://doaj.org/article/bb220183be2b4288ac3b9940563a76c0
Autor:
Timothy D. Morello, Jun Wen Zhong, Melissa L. Conerly, Chao-Jen Wong, Amy E. Campbell, Silvère M. van der Maarel, Stephen J. Tapscott, Sean C. Shadle, Sujatha Jagannathan
Publikováno v:
PLoS Genetics, Vol 13, Iss 3, p e1006658 (2017)
PLoS Genetics, 13(3)
PLoS Genetics
PLoS Genetics, 13(3)
PLoS Genetics
Facioscapulohumeral dystrophy (FSHD) is caused by the mis-expression of DUX4 in skeletal muscle cells. DUX4 is a transcription factor that activates genes normally associated with stem cell biology and its mis-expression in FSHD cells results in apop
Publikováno v:
Genes & Development. 25:997-1003
Chromatin-modifying enzymes are known to be critical components for the correct differentiation of embryonic stem cells into specific lineages, such as neurons. Recently, the role of Polycomb group proteins has been studied in the specification and d
Autor:
Scott C. Borinstein, Steve Henikoff, M. Kay Washington, Swati Biswas, Patty Trobridge, Melissa L. Conerly, William M. Grady, Slavomir Dzieciatkowski
Publikováno v:
Molecular Carcinogenesis. 49:94-103
Mouse models of intestinal tumors have advanced our understanding of the role of gene mutations in colorectal malignancy. However, the utility of these systems for studying the role of epigenetic alterations in intestinal neoplasms remains to be defi
Publikováno v:
Developmental cell. 36(4)
SummaryMost transcription factor families contain highly related paralogs generated by gene duplication, and functional divergence is generally accomplished by activation of distinct sets of genes by each member. Here we compare the molecular functio
Publikováno v:
Virology. 280(1):115-123
Natural selection of two new variants of citrus exocortis viroid (CEVd) was detected by observing tissues displaying both severe and mild symptoms from a single Gynura aurantiaca. The variants CEVd-S (severe) and CEVd-M (mild), differing by only five
Autor:
Melissa L. Conerly, Sheila S Teves, Steven Henikoff, Daniel Diolaiti, Robert N. Eisenman, Michelle Ulrich
Publikováno v:
Genome research. 20(10)
The histone variant H2A.Z has been implicated in the regulation of gene expression, and in plants antagonizes DNA methylation. Here, we ask whether a similar relationship exists in mammals, using a mouse B-cell lymphoma model, where chromatin states
Autor:
William M. Grady, Melissa L. Conerly
Epigenetics was originally defined as the interaction of genes with their environment that brings the phenotype into being. It now refers to the study of heritable changes in gene expression that occur without a change in DNA sequence. To date, the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d76a0fc568c6df2184ce03fd84c674
https://europepmc.org/articles/PMC2860849/
https://europepmc.org/articles/PMC2860849/
Autor:
Stanley R. Riddell, Bobbie Thomasson, Melissa L. Conerly, Jan Storek, Hans-Peter Kiem, Julia C. Morris
Publikováno v:
Blood. 103(2)
Lentiviral vectors are increasingly being used for transferring genes into hematopoietic stem cells (HSCs) due to their ability to transduce nondividing cells. Whereas results in in vitro studies and the nonobese diabetic/severe combined immunodefici