Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Melissa L. Alamprese"'
Autor:
Julie P. Merchant, Kuixi Zhu, Marc Y. R. Henrion, Syed S. A. Zaidi, Branden Lau, Sara Moein, Melissa L. Alamprese, Richard V. Pearse, David A. Bennett, Nilüfer Ertekin-Taner, Tracy L. Young-Pearse, Rui Chang
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-19 (2023)
Abstract Despite decades of genetic studies on late-onset Alzheimer’s disease, the underlying molecular mechanisms remain unclear. To better comprehend its complex etiology, we use an integrative approach to build robust predictive (causal) network
Externí odkaz:
https://doaj.org/article/59af61a1276a4d158efbd9462249793a
Autor:
Julie P. Merchant, Kuixi Zhu, Marc Y.R. Henrion, Syed S.A. Zaidi, Lau Branden, Sara Moein, Melissa L. Alamprese, Richard V. Pearse, David A. Bennett, Nilüfer Ertekin-Taner, Tracy L. Young-Pearse, Rui Chang
SummaryDespite decades of genetic studies on late onset Alzheimer’s disease (LOAD), the molecular mechanisms of Alzheimer’s disease (AD) remain unclear. Furthermore, different cell types in the central nervous system (CNS) play distinct roles in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11a87d44e5deedcfff4abfe4cb1558cb
https://doi.org/10.1101/2022.10.19.512949
https://doi.org/10.1101/2022.10.19.512949
Autor:
Kuixi Zhu, Qianying He, Sheng-Feng Tsai, Dinusha Maheepala Mudalige, Marc Y.R. Henrion, Syed S.A. Zaidi, Lau Branden, Andrew Tang, Mika P. Cadiz, Rachel Hodos-Nkhereanye, Sara Moein, Melissa L. Alamprese, David A. Bennett, Philip L. De Jager, John D. Frye, Nilu□fer Ertekin-Taner, Yu-Min Kuo, Patrick T. Ronaldson, Rui Chang
SummaryMicroglia, the innate immune cells of the brain, are essential determinants of late-onset Alzheimer’s Disease (LOAD) neuropathology. Here, we developed an integrative computational systems biology approach to construct causal network models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4b6baba1fad4b7c1351b1701d149bb7
https://doi.org/10.1101/2022.10.19.512953
https://doi.org/10.1101/2022.10.19.512953
Autor:
Rui, Chang, Eugenia, Trushina, Kuixi, Zhu, Syed Shujaat Ali, Zaidi, Branden M, Lau, Alexandra, Kueider-Paisley, Sara, Moein, Qianying, He, Melissa L, Alamprese, Barbora, Vagnerova, Andrew, Tang, Ramachandran, Vijayan, Yanyun, Liu, Andrew J, Saykin, Roberta D, Brinton, Rima, Kaddurah-Daouk
Publikováno v:
Alzheimer'sdementia : the journal of the Alzheimer's AssociationREFERENCES.
Late-onset Alzheimer's disease (LOAD) is a complex neurodegenerative disease characterized by multiple progressive stages, glucose metabolic dysregulation, Alzheimer's disease (AD) pathology, and inexorable cognitive decline. Discovery of metabolic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c35a2f97c41559019ad2960f2b4f76bd
https://pubmed.ncbi.nlm.nih.gov/35481667
https://pubmed.ncbi.nlm.nih.gov/35481667