Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Melissa L. Abel"'
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 24 (2021)
Minority and underresourced communities experience disproportionately high rates of fatal cancer and cardiovascular disease. The intersection of these disparities within the multidisciplinary field of cardio‐oncology is in critical need of examinat
Externí odkaz:
https://doaj.org/article/1a77dd8a481142bbbe3993a1867ecacb
Autor:
Carter M. Suryadevara, Rupen Desai, Melissa L. Abel, Katherine A. Riccione, Kristen A. Batich, Steven H. Shen, Pakawat Chongsathidkiet, Patrick C. Gedeon, Aladine A. Elsamadicy, David J. Snyder, James E. Herndon, Patrick Healy, Gary E. Archer, Bryan D. Choi, Peter E. Fecci, John H. Sampson, Luis Sanchez-Perez
Publikováno v:
OncoImmunology, Vol 7, Iss 6 (2018)
Adoptive transfer of T cells expressing chimeric antigen receptors (CARs) is an effective immunotherapy for B-cell malignancies but has failed in some solid tumors clinically. Intracerebral tumors may pose challenges that are even more significant. I
Externí odkaz:
https://doaj.org/article/c3735e2fade249f4a634f5f92b5dfa6e
Autor:
Melissa L. Abel, Nobuyuki Takahashi, Cody Peer, Christophe E. Redon, Samantha Nichols, Rasa Vilimas, Min-Jung Lee, Sunmin Lee, Meenakshi Shelat, Robbie Kattappuram, Linda Sciuto, Danielle Pinkiert, Chante Graham, Donna Butcher, Baktiar Karim, Ajit Kumar Sharma, Justin Malin, Rajesh Kumar, Christopher W. Schultz, Shubhank Goyal, Jaydira del Rivero, Manan Krishnamurthy, Deep Upadhyay, Brett Schroeder, Tristan Sissung, Manoj Tyagi, Jung Kim, Yves Pommier, Mirit Aladjem, Mark Raffeld, William Douglas Figg, Jane Trepel, Liqiang Xi, Parth Desai, Anish Thomas
Publikováno v:
Clinical Cancer Research. :OF1-OF9
Purpose: Despite promising preclinical studies, toxicities have precluded combinations of chemotherapy and DNA damage response (DDR) inhibitors. We hypothesized that tumor-targeted chemotherapy delivery might enable clinical translation of such combi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7569233e3f1b0b4fb6c6e06fd96f0032
https://doi.org/10.1158/1078-0432.ccr-23-0536
https://doi.org/10.1158/1078-0432.ccr-23-0536
Autor:
Anish Thomas, Parth Desai, Liqiang Xi, Jane Trepel, William Douglas Figg, Mark Raffeld, Mirit Aladjem, Yves Pommier, Jung Kim, Manoj Tyagi, Tristan Sissung, Brett Schroeder, Deep Upadhyay, Manan Krishnamurthy, Jaydira del Rivero, Shubhank Goyal, Christopher W. Schultz, Rajesh Kumar, Justin Malin, Ajit Kumar Sharma, Baktiar Karim, Donna Butcher, Chante Graham, Danielle Pinkiert, Linda Sciuto, Robbie Kattappuram, Meenakshi Shelat, Sunmin Lee, Min-Jung Lee, Rasa Vilimas, Samantha Nichols, Christophe E. Redon, Cody Peer, Nobuyuki Takahashi, Melissa L. Abel
Trial protocol dose limiting toxicity criteria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::719d1224a7d725404c43187779ea8040
https://doi.org/10.1158/1078-0432.23183857.v1
https://doi.org/10.1158/1078-0432.23183857.v1
Autor:
Anish Thomas, Parth Desai, Liqiang Xi, Jane Trepel, William Douglas Figg, Mark Raffeld, Mirit Aladjem, Yves Pommier, Jung Kim, Manoj Tyagi, Tristan Sissung, Brett Schroeder, Deep Upadhyay, Manan Krishnamurthy, Jaydira del Rivero, Shubhank Goyal, Christopher W. Schultz, Rajesh Kumar, Justin Malin, Ajit Kumar Sharma, Baktiar Karim, Donna Butcher, Chante Graham, Danielle Pinkiert, Linda Sciuto, Robbie Kattappuram, Meenakshi Shelat, Sunmin Lee, Min-Jung Lee, Rasa Vilimas, Samantha Nichols, Christophe E. Redon, Cody Peer, Nobuyuki Takahashi, Melissa L. Abel
Study Representativeness
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1134469c3d0836c8a00a656b51d038b1
https://doi.org/10.1158/1078-0432.23183836
https://doi.org/10.1158/1078-0432.23183836
Autor:
Anish Thomas, Parth Desai, Liqiang Xi, Jane Trepel, William Douglas Figg, Mark Raffeld, Mirit Aladjem, Yves Pommier, Jung Kim, Manoj Tyagi, Tristan Sissung, Brett Schroeder, Deep Upadhyay, Manan Krishnamurthy, Jaydira del Rivero, Shubhank Goyal, Christopher W. Schultz, Rajesh Kumar, Justin Malin, Ajit Kumar Sharma, Baktiar Karim, Donna Butcher, Chante Graham, Danielle Pinkiert, Linda Sciuto, Robbie Kattappuram, Meenakshi Shelat, Sunmin Lee, Min-Jung Lee, Rasa Vilimas, Samantha Nichols, Christophe E. Redon, Cody Peer, Nobuyuki Takahashi, Melissa L. Abel
Pharmacokinetic assessment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06619753b143d9112a4bb0c3cb9b8e1
https://doi.org/10.1158/1078-0432.23183851.v1
https://doi.org/10.1158/1078-0432.23183851.v1
Autor:
Anish Thomas, Parth Desai, Liqiang Xi, Jane Trepel, William Douglas Figg, Mark Raffeld, Mirit Aladjem, Yves Pommier, Jung Kim, Manoj Tyagi, Tristan Sissung, Brett Schroeder, Deep Upadhyay, Manan Krishnamurthy, Jaydira del Rivero, Shubhank Goyal, Christopher W. Schultz, Rajesh Kumar, Justin Malin, Ajit Kumar Sharma, Baktiar Karim, Donna Butcher, Chante Graham, Danielle Pinkiert, Linda Sciuto, Robbie Kattappuram, Meenakshi Shelat, Sunmin Lee, Min-Jung Lee, Rasa Vilimas, Samantha Nichols, Christophe E. Redon, Cody Peer, Nobuyuki Takahashi, Melissa L. Abel
Purpose:Despite promising preclinical studies, toxicities have precluded combinations of chemotherapy and DNA damage response (DDR) inhibitors. We hypothesized that tumor-targeted chemotherapy delivery might enable clinical translation of such combin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc7577de8e937edbaabfad8bf2398a84
https://doi.org/10.1158/1078-0432.c.6664579.v1
https://doi.org/10.1158/1078-0432.c.6664579.v1
Autor:
Jeffrey W. Tyner, Emily A. Stevens, Marc M. Loriaux, Christopher A. Eide, Melissa L. Abel, Samantha L. Savage, Swaleh Bahamadi, Peter Greenberg, Jason Gotlib, Jason C. Paik, Jason D. MacManiman, Samuel B. Luty, Julia E. Maxson
Purpose: Colony-stimulating factor 3 receptor (CSF3R) mutations have been identified in the majority of chronic neutrophilic leukemia (CNL) and a smaller percentage of atypical chronic myeloid leukemia (aCML) cases. Although CSF3R point mutations (e.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8c1853eafabcb5874c8c7658362c47
https://doi.org/10.1158/1078-0432.c.6524754
https://doi.org/10.1158/1078-0432.c.6524754
Autor:
Jeffrey W. Tyner, Brian J. Druker, Nathanael S. Gray, Richard E. Middleton, Oliver Hantschel, Jerald Radich, Shannon K. McWeeney, Beth Wilmot, Daniel Bottomly, Seamus B. Hughes, Julie Gorenstein, Huahang Sun, Samuel B. Luty, Sina Reckel, Xianming Deng, Jinhua Wang, Melissa L. Abel, Julia E. Maxson
The amount of genomic information about leukemia cells currently far exceeds our overall understanding of the precise genetic events that ultimately drive disease development and progression. Effective implementation of personalized medicine will req
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a5323f8724fb772bb0bb7b75c0e008
https://doi.org/10.1158/0008-5472.c.6507081
https://doi.org/10.1158/0008-5472.c.6507081
Autor:
Jeffrey W. Tyner, Brian J. Druker, Nathanael S. Gray, Richard E. Middleton, Oliver Hantschel, Jerald Radich, Shannon K. McWeeney, Beth Wilmot, Daniel Bottomly, Seamus B. Hughes, Julie Gorenstein, Huahang Sun, Samuel B. Luty, Sina Reckel, Xianming Deng, Jinhua Wang, Melissa L. Abel, Julia E. Maxson
Enzymatic IC50 of potential targets for XMD8-87 and XMD16-5.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ff4468ddf8b6fd949e65b2f1076756
https://doi.org/10.1158/0008-5472.22406451.v1
https://doi.org/10.1158/0008-5472.22406451.v1