Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Melissa L, Vadnais"'
Autor:
Khoa Le, Dennis R. Burton, Michael F. Criscitiello, Waithaka Mwangi, Devin Sok, Chi-Hui Liang, Vaughn V. Smider, Jennifer Ruiz, Melissa L. Vadnais, Andrew B. Ward, Karen L. Saye-Francisco, Zachary T. Berndsen, Jonathan L. Torres, Ian A. Wilson, Leopold Kong, Alejandra Ramos, Joseph G. Jardine, Robyn L. Stanfield, Patricia L. Chen
Publikováno v:
Nature
Immunization of cows with a recombinant HIV envelope protein leads to the rapid development of potent, broadly neutralizing antibodies against HIV. HIV infection gives rise to the generation of broadly neutralizing antibodies in a subset of infected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aca624df97601159430978411e3e46a
http://europepmc.org/articles/PMC5812458
http://europepmc.org/articles/PMC5812458
Autor:
Melissa L. Vadnais, Vaughn V. Smider
Publikováno v:
Current Opinion in Structural Biology. 38:62-67
Cow antibodies are unusual in having an exceptionally long third complementarity determining region of the heavy chain (CDR H3). These CDR H3s have a multitude of cysteines and form a distinct domain characterized by a β-ribbon “stalk” and disul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41bd8249150babfd73dec69ebf682149
https://doi.org/10.1016/j.sbi.2016.05.004
https://doi.org/10.1016/j.sbi.2016.05.004
Autor:
George L. Gerton, Melissa L. Vadnais
The functions of the sperm are to transport and contribute a haploid copy of the paternal genome to the egg and initiate development of the embryo. The compact and compartmentalized spermatozoon can be divided into two major, morphologically distinct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::583ba4b5675707ef618c187d73206721
https://doi.org/10.1016/b978-0-12-801238-3.64438-0
https://doi.org/10.1016/b978-0-12-801238-3.64438-0
Publikováno v:
Protein Therapeutics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61678a4c42f93a891023ed198afebb1f
https://doi.org/10.1002/9783527699124.ch4
https://doi.org/10.1002/9783527699124.ch4
Autor:
Melissa L. Vadnais, Takashi W. Ijiri, George L. Gerton, Andy P. Huang, Lonny R. Levin, Angel M. Lin, Jochen Buck
Publikováno v:
Andrology
Caput epididymal wild-type spermatozoa and cauda epididymal spermatozoa from mice null for the adenylyl cyclase Adcy10 gene are immotile unless stimulated by a membrane-permeant cyclic AMP analogue. Both types of spermatozoa exhibit flagellar angulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a774e2d1dda9b87fc2dfd103badaa6c
https://doi.org/10.1111/j.2047-2927.2013.00147.x
https://doi.org/10.1111/j.2047-2927.2013.00147.x
Autor:
Wenlei Cao, Angel M. Lin, Tanya Merdiushev, Andy P. Huang, George L. Gerton, Melissa L. Vadnais, Takashi W. Ijiri
Publikováno v:
Molecular Reproduction and Development
SUMMARY Triosephosphate isomerase 1 (TPI1) is a member of the glycolytic pathway, which is a critical source of energy for motility in mouse sperm. By immunoblotting, we detected two male, germ line-specific TPI1 bands (Mr 33,400 and 30,800) as well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91efd0699bbeed4c4d751ad00d95fea6
https://doi.org/10.1002/mrd.22217
https://doi.org/10.1002/mrd.22217
Publikováno v:
Biology of Reproduction. 79:1129-1134
The family of mammalian cysteine-rich secretory proteins (CRISP) have been well characterized in the rat, mouse, and human. Here we report the molecular cloning and expression analysis of CRISP1, CRISP2, and CRISP3 in the boar. A partial sequence pub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc65867de1c5842f81e4c1ea9d84d639
https://doi.org/10.1095/biolreprod.108.070177
https://doi.org/10.1095/biolreprod.108.070177
Publikováno v:
Archives of Andrology. 53:109-123
Spermatozoa are required to undergo the processes of capacitation before they obtain fertilizing ability. The molecular changes of capacitation are still not fully understood. However, it is accepted that capacitation is a sequential process involvin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3596b6b8646bff6c7b2cd4d78a1fe1a7
https://doi.org/10.1080/01485010701329386
https://doi.org/10.1080/01485010701329386
Autor:
Kenneth P. Roberts, Melissa L. Vadnais
Publikováno v:
Journal of Andrology. 28:416-422
Porcine seminal plasma (SP) has been shown to contain factors that have a decapacitative or capacitation-inhibiting effect on sperm. The objectives of the present study were to compare the capacitative changes observed in cooled sperm with those seen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47414e7741cad6934c60289ca2a6a8e2
https://doi.org/10.2164/jandrol.106.001826
https://doi.org/10.2164/jandrol.106.001826
Autor:
Osama Al-Alao, Melissa L. Vadnais, Lisa Haig-Ladewig, Haig Aghajanian, Angel M. Lin, George L. Gerton, Wenlei Cao
While most ATP, the main energy source driving sperm motility, is derived from glycolysis and oxidative phosphorylation, the metabolic demands of the cell require the efficient use of power stored in high-energy phosphate bonds. In times of high ener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::417246ca327391e9d49ff5b161e38c70
https://europepmc.org/articles/PMC4094002/
https://europepmc.org/articles/PMC4094002/