Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Melissa Kirigiti"'
Autor:
Darian T. Carroll, Allie Miller, Jennifer Fuhr, Joseph M. Elsakr, Valerie Ricciardi, Alexa N. Del Bene, Stedman Stephens, Evan Krystofiak, Sarah R. Lindsley, Melissa Kirigiti, Diana L. Takahashi, Tyler A. Dean, Stephanie R. Wesolowski, Carrie E. McCurdy, Jacob E. Friedman, Kjersti M. Aagaard, Paul Kievit, Maureen Gannon
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionUsing a non-human primate (NHP) model of maternal Western-style diet (mWSD) feeding during pregnancy and lactation, we previously reported altered offspring beta:alpha cell ratio in vivo and insulin hyper-secretion ex vivo. Mitochondria a
Externí odkaz:
https://doaj.org/article/2aefe612d931437fb2599f63ef8e7bf0
Autor:
Alison H Affinati, Paul V Sabatini, Cadence True, Abigail J Tomlinson, Melissa Kirigiti, Sarah R Lindsley, Chien Li, David P Olson, Paul Kievit, Martin G Myers, Alan C Rupp
Publikováno v:
eLife, Vol 10 (2021)
The ventromedial hypothalamic nucleus (VMH) controls diverse behaviors and physiologic functions, suggesting the existence of multiple VMH neural subtypes with distinct functions. Combing translating ribosome affinity purification with RNA-sequencing
Externí odkaz:
https://doaj.org/article/8faf75d4819346d7882986d140a64fa5
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Maternal obesity and consumption of a high-fat diet (HFD) during pregnancy has a negative impact on offspring, including an increased risk for the development of obesity in adolescence. The mechanism for this transferred metabolic risk is unclear, bu
Externí odkaz:
https://doaj.org/article/17c468c6500d48dd87c9516b11857480
Autor:
Darian T. Carroll, Joseph M. Elsakr, Allie Miller, Jennifer Fuhr, Sarah R. Lindsley, Melissa Kirigiti, Diana L. Takahashi, Tyler A. Dean, Stephanie R. Wesolowski, Carrie E. McCurdy, Jacob E. Friedman, Kjersti M. Aagaard, Paul Kievit, Maureen Gannon
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism.
Maternal overnutrition is associated with increased susceptibility to Type 2 Diabetes in the offspring. Rodent models have shown that maternal overnutrition influences islet function in offspring. To determine whether maternal Western style diet (WSD
Autor:
DARIAN T. CARROLL, JOSEPH M. ELSAKR, VALERIE F. RICCIARDI, JENNIFER C. DUNN, SARAH R. LINDSLEY, TYLER DEAN, MELISSA KIRIGITI, DIANA L. TAKAHASHI, STEPHANIE R. WESOLOWSKI, CARRIE E. MCCURDY, PAUL KIEVIT, KJERSTI M. AAGAARD, JACOB E. FRIEDMAN, MAUREEN GANNON
Publikováno v:
Diabetes. 71
The Developmental Origins of Health and Disease hypothesis states that the intrauterine environment influences postnatal health and adult disease susceptibility. In the United States, over 30% of women of childbearing age are obese, in part due to We
Autor:
Melissa Kirigiti, Rikley Buckingham, Kevin L. Grove, Anna Secher, Lotte Bjerre Knudsen, Niels Vrang, Sarah Juel Paulsen, Kristy M. Heppner, Charles Pyke
Publikováno v:
Endocrinology. 156:255-267
Glucagon-like peptide-1 (GLP-1) is released from endocrine L-cells lining the gut in response to food ingestion. However, GLP-1 is also produced in the nucleus of the solitary tract, where it acts as an anorectic neurotransmitter and key regulator of
Autor:
Shin J, Lee, Melissa, Kirigiti, Sarah R, Lindsley, Alberto, Loche, Christopher J, Madden, Shaun F, Morrison, M Susan, Smith, Kevin L, Grove
Publikováno v:
The Journal of comparative neurology. 521(8)
The dorsomedial hypothalamus (DMH) has long been implicated in feeding behavior and thermogenesis. The DMH contains orexigenic neuropeptide Y (NPY) neurons, but the role of these neurons in the control of energy homeostasis is not well understood. NP
Publikováno v:
Journal of neuroendocrinology. 23(1)
Lactation results in negative energy balance in the rat leading to decreased gonadotrophin-releasing hormone (GnRH) release and anoestrus. Inhibited GnRH release may be a result of decreased stimulatory tone from neuropeptides critical for GnRH neuro