Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Melissa Kasheta"'
Autor:
Craig J. Ceol, Deborah K. Morrison, Leonard I. Zon, Melissa Kasheta, Caitlin Bourque, Robert L. Kortum, James V. Neiswender
The receptor tyrosine kinase KIT promotes survival and migration of melanocytes during development, and excessive KIT activity hyperactivates the RAS/MAPK pathway and can drive formation of melanomas, most notably of rare melanomas that occur on vola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9703cc6c948eef6af983a3ceddd13662
https://doi.org/10.1158/0008-5472.c.6510162.v1
https://doi.org/10.1158/0008-5472.c.6510162.v1
Autor:
Craig J. Ceol, Deborah K. Morrison, Leonard I. Zon, Melissa Kasheta, Caitlin Bourque, Robert L. Kortum, James V. Neiswender
This file contains Supplementary Figures S1-S9 with accompanying legends. Supplementary Fig. S1 examines the relationship between KIT expression and BRAFV600E mutations in TCGA human melanoma samples. Supplementary Fig. S2 shows the rescue of melanoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0307b9a6fddd3b95f62e590f92256833
https://doi.org/10.1158/0008-5472.22418562.v1
https://doi.org/10.1158/0008-5472.22418562.v1
Autor:
Craig J. Ceol, Deborah K. Morrison, Leonard I. Zon, Melissa Kasheta, Caitlin Bourque, Robert L. Kortum, James V. Neiswender
Supplementary Table S1 and S2 show the BRET50 data for Supplementary Fig. S5A and S6B, respectively. Supplementary Table S3 and S4 show further analyses of the relationship between KIT expression and several clinical parameters of melanoma progressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a40cc3038b2b0c05eb4dd86b5d084880
https://doi.org/10.1158/0008-5472.22418559.v1
https://doi.org/10.1158/0008-5472.22418559.v1
Autor:
Craig J. Ceol, Leonard I. Zon, Melissa Kasheta, Deborah K. Morrison, Robert L. Kortum, James Neiswender, Caitlin Bourque
Publikováno v:
Cancer Research. 77:5820-5830
The receptor tyrosine kinase KIT promotes survival and migration of melanocytes during development, and excessive KIT activity hyperactivates the RAS/MAPK pathway and can drive formation of melanomas, most notably of rare melanomas that occur on vola
Autor:
Alysia Bryll, Eli Freiman, Craig J. Ceol, Arlin B. Rogers, David L. Stachura, Riadh Lobbardi, Yariv Houvras, Melissa Kasheta, Finola E. Moore, David M. Langenau, Corrie A. Painter
Publikováno v:
The Journal of Experimental Medicine
Kasheta et al. report the identification of T reg–like cells in zebrafish, a means to track and live-image these cells, and foxp3a-deficient mutants that display lymphoproliferation, severe inflammation, and other hallmarks of T reg deficiency synd
Autor:
Ravi Mylvaganam, Qin Tang, Jeffrey A. Yoder, Riadh Lobbardi, Mauricio Cortes, Ruslan I. Sadreyev, Finola E. Moore, Esha Jain, Melissa Kasheta, Jessica S. Blackburn, Craig J. Ceol, Elaine G. Garcia, John C. Moore, Amaris J. Garcia, David M. Langenau, Christina C. Luo, Aleksey Molodtsov, Trista E. North
Publikováno v:
The Journal of Experimental Medicine
Moore et al. reports the first single-cell gene expression analysis in zebrafish blood to distinguish major blood lineages, identify new cell types, and delineate heterogeneity in T cell leukemia.
Hematopoiesis culminates in the production of fu
Hematopoiesis culminates in the production of fu
Autor:
Benjamin J. Metcalf, Melissa Kasheta, Caitlin Kasala-Hallinan, Dollnovan Tran, Amitinder Kaur, David H. O’Connor, Cristian Apetrei, Julie A. Karl, Zichun Wang, R. Paul Johnson, James G. Else
Publikováno v:
Immunogenetics. 67:447-461
Although immune pressure exerted by MHC class I-restricted cytotoxic T lymphocytes (CTL) are an important determinant of outcome in pathogenic HIV and SIV infection, lack of data on MHC class I genes has hampered study of its role in natural hosts wi
Publikováno v:
Developmental Cell. 33:631-643
SummaryEfficient regeneration following injury is critical for maintaining tissue function and enabling organismal survival. Cells reconstituting damaged tissue are often generated from resident stem or progenitor cells or from cells that have dediff
Autor:
James V, Neiswender, Robert L, Kortum, Caitlin, Bourque, Melissa, Kasheta, Leonard I, Zon, Deborah K, Morrison, Craig J, Ceol
Publikováno v:
Cancer research. 77(21)
The receptor tyrosine kinase KIT promotes survival and migration of melanocytes during development, and excessive KIT activity hyperactivates the RAS/MAPK pathway and can drive formation of melanomas, most notably of rare melanomas that occur on vola
Autor:
Erin P. Ribka, Mary B. Barnes, David C. Montefiori, Melissa Pattison, Thaidra Gaufin, Ivona Pandrea, Jeanne MacFarland, Amitinder Kaur, Melissa Kasheta, Ruy M. Ribeiro, Coty Tatum, Rajeev Gautam, Cristian Apetrei
Publikováno v:
Blood. 113:4250-4261
We investigated the impact of rhesus macaque (RM) B-cell depletion before inoculation with the isolate SIVsmmD215. Seven RMs were treated every 3 weeks with 50 mg/kg of an anti-CD20 antibody (rituximab) starting 7 days before inoculation for 2 (n = 4