Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Melissa K. Ritchie"'
Publikováno v:
Acta Crystallographica Section E, Vol 70, Iss 3, Pp m82-m82 (2014)
The title compound, [Ir(C5H10NO2)H(C3H9P)3]PF6·0.675CH2Cl2, an iridium compound with a meridional arrangement of PMe3 groups, O,N-bidentate coordination of d-valine and with a hydride ligand trans to the N atom is compared with the l-valine complex
Externí odkaz:
https://doaj.org/article/0f4284cf31424b97bd897199cb39d444
Autor:
Jill E. Clodfelter, Brian E. Fulp, Charles W. Pemble, Lynnette C. Johnson, Cristina M. Furdui, Melissa K. Ritchie, W. Todd Lowther, Steven J. Kridel
Publikováno v:
Journal of Biological Chemistry. 291:3520-3530
The type I fatty acid synthase (FASN) is responsible for the de novo synthesis of palmitate. Chain length selection and release is performed by the C-terminal thioesterase domain (TE1). FASN expression is up-regulated in cancer, and its activity leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::898537d2920e3baf0e1a38a4ae84f56c
https://doi.org/10.1074/jbc.m115.702597
https://doi.org/10.1074/jbc.m115.702597
Autor:
Melissa K, Ritchie, Lynnette C, Johnson, Jill E, Clodfelter, Charles W, Pemble, Brian E, Fulp, Cristina M, Furdui, Steven J, Kridel, W Todd, Lowther
Publikováno v:
The Journal of biological chemistry. 291(7)
The type I fatty acid synthase (FASN) is responsible for the de novo synthesis of palmitate. Chain length selection and release is performed by the C-terminal thioesterase domain (TE1). FASN expression is up-regulated in cancer, and its activity leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a912c918b98fb7198fa92562e1767ac8
https://pubmed.ncbi.nlm.nih.gov/26663084
https://pubmed.ncbi.nlm.nih.gov/26663084
Publikováno v:
Cancer Research. 70:2675-2675
Human thioesterase II (TE2) may limit the anti-tumour potential of fatty acid synthase (FASN) inhibitors designed to target endogenous thioesterase (TE1) domain of FASN in breast cancer. Recent studies have firmly established the anti-tumour effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b3a1f783df6f325d2e0c64cd9a35892
https://doi.org/10.1158/1538-7445.am10-2675
https://doi.org/10.1158/1538-7445.am10-2675