Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Melissa K, Thomas"'
Autor:
Nicholas R. Powell, Tiebing Liang, Joseph Ipe, Sha Cao, Todd C. Skaar, Zeruesenay Desta, Hui-Rong Qian, Philip J. Ebert, Yu Chen, Melissa K. Thomas, Naga Chalasani
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
This study characterizes expression of pharmacogenes across the histological NAFLD severity spectrum. Here, the authors show the downregulation of CYP2C19 in NAFLD which supports developing personalized medicine approaches for drugs sensitive to meta
Externí odkaz:
https://doaj.org/article/a90be45cc8cb455db34c7afe0b5d1181
Publikováno v:
Family & Community Health. 46:192-202
Autor:
Tim Heise, J. Hans DeVries, Shweta Urva, Jing Li, Edward J. Pratt, Melissa K. Thomas, Kieren J. Mather, Chrisanthi A. Karanikas, Julia Dunn, Axel Haupt, Zvonko Milicevic, Tamer Coskun
Publikováno v:
Diabetes Care. 46:998-1004
OBJECTIVE To evaluate the effects of tirzepatide on body composition, appetite, and energy intake to address the potential mechanisms involved in body weight loss with tirzepatide. RESEARCH DESIGN AND METHODS In a secondary analysis of a randomized,
Autor:
Shweta, Urva, Tamer, Coskun, Mei Teng, Loh, Yu, Du, Melissa K, Thomas, Sirel, Gurbuz, Axel, Haupt, Charles T, Benson, Martha, Hernandez-Illas, David A, D'Alessio, Zvonko, Milicevic
Publikováno v:
The Lancet. 400:1869-1881
Treating hyperglycaemia and obesity in individuals with type 2 diabetes using multi-receptor agonists can improve short-term and long-term outcomes. LY3437943 is a single peptide with agonist activity for glucagon, glucose-dependent insulinotropic po
Autor:
Shailesh Kumar Gupta, Agata Wesolowska-Andersen, Anna K. Ringgaard, Himjyot Jaiswal, Luyan Song, Benoit Hastoy, Camilla Ingvorsen, Amir Taheri-Ghahfarokhi, Björn Magnusson, Marcello Maresca, Rikke R. Jensen, Nicola L. Beer, Johannes J. Fels, Lars G. Grunnet, Melissa K. Thomas, Anna L. Gloyn, Ryan Hicks, Mark I. McCarthy, Mattias Hansson, Christian Honoré
Publikováno v:
Stem Cell Research, Vol 29, Iss , Pp 220-231 (2018)
Recent studies have reported significant advances in the differentiation of human pluripotent stem cells to clinically relevant cell types such as the insulin producing beta-like cells and motor neurons. However, many of the current differentiation p
Externí odkaz:
https://doaj.org/article/388e243f0c3f452f8d7167f3e381a0f1
Autor:
Hua V. Lin, Jingru Wang, Jie Wang, Weiji Li, Xuesong Wang, James T. Alston, Melissa K. Thomas, Daniel A. Briere, Samreen K. Syed, Alexander M. Efanov
Publikováno v:
Molecular Metabolism, Vol 11, Iss , Pp 205-211 (2018)
Objective: GPR142 agonists are being pursued as novel diabetes therapies by virtue of their insulin secretagogue effects. But it is undetermined whether GPR142's functions in pancreatic islets are limited to regulating insulin secretion. The current
Externí odkaz:
https://doaj.org/article/51a98efe956c4a619df0f0a69c4863d8
Autor:
Tim Heise, J Hans DeVries, Shweta Urva, Jing Li, Edward John Pratt, Melissa K. Thomas, Kieren Mather, Julia Dunn, Axel Haupt, Zvonko Milicevic, Tamer Coskun
Publikováno v:
Diabetologie und Stoffwechsel.
Autor:
Katelyn Brown, Laura Fernández Landó, Brandon Bergman, Melissa K. Thomas, Bing Liu, Clare Lee, Michael A. Nauck
Publikováno v:
Diabetologie und Stoffwechsel.
Publikováno v:
Journal of the Endocrine Society. 7
Context Tirzepatide is a glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist approved for treatment of type 2 diabetes (T2D). SURPASS-1, a phase 3 trial of tirzepatide monotherapy in people with early T2D, enable
Autor:
Tamer Coskun, Zvonko Milicevic, Axel Haupt, Julia Dunn, Chrisanthi A. Karanikas, Kieren J. Mather, Melissa K. Thomas, Edward J. Pratt, Jing Li, Shweta Urva, J Hans DeVries, Tim Heise
OBJECTIVE: To evaluate effects of tirzepatide on body composition, appetite and energy intake to address the potential mechanisms involved in body weight loss with tirzepatide. RESEARCH DESIGN AND METHODS: In a secondary analysis of a randomized, dou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8174afe34e453bf3a6daeece5fa35b3d
https://doi.org/10.2337/figshare.21984596.v1
https://doi.org/10.2337/figshare.21984596.v1