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pro vyhledávání: '"Melissa Jurica"'
Autor:
Constantin Cretu, Patricia Gee, Xiang Liu, Anant Agrawal, Tuong-Vi Nguyen, Arun K. Ghosh, Andrew Cook, Melissa Jurica, Nicholas A. Larsen, Vladimir Pena
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Chemical modulation of intron selection has emerged as a route for cancer therapy. Here, structures of the U2 snRNP’s SF3B module and of prespliceosome- both in complexes with splicing modulators- provide insight into the mechanisms of intron recog
Externí odkaz:
https://doaj.org/article/9f060ae1a19640e593633f074975b41b