Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Melissa J. Harnois"'
Autor:
Melissa J. Harnois, Richard Barfield, Maria Dennis, Nicole Rodgers, Justin Pollara, Connor S. Spies, Laurie D. Snyder, Cliburn Chan, Annette M. Jackson, Scott M. Palmer, Sallie R. Permar
Publikováno v:
JHLT Open, Vol 5, Iss , Pp 100113- (2024)
Background: Cytomegalovirus (CMV) is the most common viral infection among lung transplant recipients and is associated with chronic lung allograft dysfunction. There is a need for better therapeutics as well as biomarkers to enable effective stratif
Externí odkaz:
https://doaj.org/article/c5618eb61e9b4a18b13209e6e2b2f783
Autor:
Sarah M. Valencia, Eric Rochat, Melissa J. Harnois, Maria Dennis, Helen S. Webster, Bhavna Hora, Amit Kumar, Hsuan-Yuan (Sherry) Wang, Leike Li, Daniel Freed, Ningyan Zhang, Zhiqiang An, Dai Wang, Sallie R. Permar
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-8 (2023)
Abstract Human Cytomegalovirus (HCMV) is the leading infectious congenital infection globally and the most common viral infection in transplant recipients, therefore identifying a vaccine for HCMV is a top priority. Humoral immunity is a correlate of
Externí odkaz:
https://doaj.org/article/1b2425aaf8034f56a1e1dfae57c8df13
Autor:
Jeremy J. Ratiu, William E. Barclay, Elliot Lin, Qun Wang, Sebastian Wellford, Naren Mehta, Melissa J. Harnois, Devon DiPalma, Sumedha Roy, Alejandra V. Contreras, Mari L. Shinohara, David Wiest, Yuan Zhuang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
T cell development involves extensive proliferation of developing thymocytes. Here, the authors demonstrate that the transcription factor Zfp335 regulates the survival post-β-selection thymocytes via the cGAS/STING pathway.
Externí odkaz:
https://doaj.org/article/1986148c7cbb4df0b7b4c12b62079982
Autor:
Eleanor C. Semmes, Itzayana G. Miller, Courtney E. Wimberly, Caroline T. Phan, Jennifer A. Jenks, Melissa J. Harnois, Stella J. Berendam, Helen Webster, Jillian H. Hurst, Joanne Kurtzberg, Genevieve G. Fouda, Kyle M. Walsh, Sallie R. Permar
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 16 (2022)
Human cytomegalovirus (HCMV) is the most common congenital infection and a leading cause of stillbirth, neurodevelopmental impairment, and pediatric hearing loss worldwide. Development of a maternal vaccine or therapeutic to prevent congenital HCMV h
Externí odkaz:
https://doaj.org/article/01cf6c8bdde642388fe306afd43ea024
Characterization of Plasma Immunoglobulin G Responses in Elite Neutralizers of Human Cytomegalovirus
Autor:
Melissa J Harnois, Maria Dennis, Dagmar Stöhr, Sarah M Valencia, Nicole Rodgers, Eleanor C Semmes, Helen S Webster, Jennifer A Jenks, Richard Barfield, Justin Pollara, Cliburn Chan, Christian Sinzger, Sallie R Permar
Publikováno v:
J Infect Dis
Background Human cytomegalovirus (HCMV) is the most common infectious complication of organ transplantation and cause of birth defects worldwide. There are limited therapeutic options and no licensed vaccine to prevent HCMV infection or disease. To i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b842658404812c2b892fa923137a1b0
https://doi.org/10.1093/infdis/jiac341
https://doi.org/10.1093/infdis/jiac341
Autor:
Melissa J. Harnois, Maria Dennis, Dagmar Stöhr, Sarah M. Valencia, Nicole Rodgers, Eleanor C. Semmes, Helen S. Webster, Jennifer A. Jenks, Richard Barfield, Justin Pollara, Cliburn Chan, Christian Sinzger, Sallie R. Permar
BackgroundHuman cytomegalovirus (HCMV) is the most common infectious complication of organ transplantation and cause of birth defects worldwide. There are limited therapeutic options and no licensed vaccine to prevent HCMV infection or disease. To in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3008b9941b4bf22b4b938edc47422e77
https://doi.org/10.1101/2022.06.06.22275103
https://doi.org/10.1101/2022.06.06.22275103
Autor:
Jennifer A. Jenks, Sharmi Amin, Madeline R. Sponholtz, Amit Kumar, Daniel Wrapp, Sravani Venkatayogi, Joshua J. Tu, Krithika Karthigeyan, Sarah M. Valencia, Megan Connors, Melissa J. Harnois, Bhavna Hora, Eric Rochat, Jason S. McLellan, Kevin Wiehe, Sallie R. Permar
Publikováno v:
PLOS Pathogens. 19:e1011107
Cytomegalovirus (CMV) is a leading cause of infant hearing loss and neurodevelopmental delay, but there are no clinically licensed vaccines to prevent infection, in part due to challenges eliciting neutralizing antibodies. One of the most well-studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::646e7879a10fc992da1a418899b1b20d
https://doi.org/10.1371/journal.ppat.1011107
https://doi.org/10.1371/journal.ppat.1011107
Autor:
Eleanor C. Semmes, Itzayana G. Miller, Jennifer A. Jenks, Courtney E. Wimberly, Stella J. Berendam, Melissa J. Harnois, Helen Webster, Jillian H. Hurst, Joanne Kurtzberg, Genevieve G Fouda, Kyle M. Walsh, Sallie R. Permar
Human cytomegalovirus (HCMV) is the most common congenital infection and a leading cause of stillbirth, neurodevelopmental impairment, and pediatric hearing loss worldwide. Development of a maternal vaccine or therapeutic to prevent congenital infect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce1044afbf4c8714b41f9238c5a9d9dc
https://doi.org/10.1101/2021.12.05.21267312
https://doi.org/10.1101/2021.12.05.21267312
Autor:
Jeremy J Ratiu, William Barclay, Qun Wang, Naren Mehta, Melissa J Harnois, Devon DiPalma, Sebastian Wellford, Sumedha Roy, Alejandra V Contreras, David Wiest, Yuan Zhuang
Production of a diverse peripheral T cell compartment requires massive expansion of the bone marrow progenitors that seed the thymus. There are two main phases of expansion during T cell development, following T lineage commitment at the DN2 stage an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2a60663eaa4b9d8992de715a524f621
https://doi.org/10.1101/2021.12.03.471158
https://doi.org/10.1101/2021.12.03.471158