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pro vyhledávání: '"Melissa J. Glenn"'
Overtraining Strengthens the Visual Discrimination Memory Trace Outside the Hippocampus in Male Rats
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2021)
The hippocampus (HPC) may compete with other memory systems when establishing a representation, a process termed overshadowing. However, this overshadowing may be mitigated by repeated learning episodes, making a memory resistant to post-training hip
Externí odkaz:
https://doaj.org/article/cadc8eab392e4d1e917fcf9986ec401a
Autor:
Sarah J.E. Wong-Goodrich, Tiffany J. Mellott, Melissa J. Glenn, Jan K. Blusztajn, Christina L. Williams
Publikováno v:
Neurobiology of Disease, Vol 30, Iss 2, Pp 255-269 (2008)
Prenatal choline supplementation (SUP) protects adult rats against spatial memory deficits observed after excitotoxin-induced status epilepticus (SE). To examine the mechanism underlying this neuroprotection, we determined the effects of SUP on a var
Externí odkaz:
https://doaj.org/article/3e9d41a85c094fe383336c4b78bfa5fb
Autor:
Amanda L Doak, Melissa J. Glenn, Ariel A Batallán Burrowes, Waylin Yu, Amanda Norchi, Lisa Blackmer-Raynolds
Publikováno v:
Genes, Brain and Behavior. 21
Mutations in the disrupted in schizophrenia-1 (DISC1) gene are associated with an increased risk of developing psychological disorders including schizophrenia, bipolar disorder, and depression. Assessing the impact of knocking out genes, like DISC1,
Publikováno v:
Journal of Neuroscience Methods. 290:133-144
Mild traumatic brain injuries (mTBI) are an increasing health concern due to persistent behavioral and neurological effects. To better understand these effects, researchers frequently rely on animal injury models. Existing models, however, may not ad
Publikováno v:
Pharmacology Biochemistry and Behavior. 132:125-135
The present study explored the effects of supplementing male rats with either choline, omega-3 fatty acids, or phytoestrogens, from weaning into early adulthood, on emotionality and hippocampal plasticity. Because of the neuroprotective properties of
Choline is essential to the development and function of the central nervous system and supplemental choline during development is neuroprotective against a variety of insults, including neurotoxins like dizocilpine (MK-801). MK-801 is an NMDA recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf88b932f64be4271658c775f28fac6f
https://europepmc.org/articles/PMC5605469/
https://europepmc.org/articles/PMC5605469/
Autor:
Sarah J.E. Wong-Goodrich, Jan Krzysztof Blusztajn, Tiffany J. Mellott, Christina M. Tognoni, Melissa J. Glenn, Christina L. Williams
Publikováno v:
Brain Research. 1413:84-97
Choline is a vital nutrient needed during early development for both humans and rodents. Severe dietary choline deficiency during pregnancy leads to birth defects, while more limited deficiency during mid- to late pregnancy causes deficits in hippoca
Publikováno v:
Endocrinology. 152:946-956
Evidence from lesion and inactivation studies suggests that the hippocampus (HPC) and dorsal striatum compete for control over navigation behavior, and there is some evidence in males that the structure with greater relative activation controls behav
Autor:
Melissa J. Glenn, Sarah J.E. Wong-Goodrich, Erin M. Gibson, Elizabeth D. Kirby, Tiffany J. Mellott, Jan Krzysztof Blusztajn, Christina L. Williams
Publikováno v:
Brain Research. 1237:110-123
Supplemental choline in the maternal diet produces a lasting enhancement in memory in offspring that resists age-related decline and is accompanied by neuroanatomical, neurophysiological and neurochemical changes in the hippocampus. The present study
Autor:
Tiffany J. Mellott, Sarah J.E. Wong-Goodrich, Melissa J. Glenn, Jan Krzysztof Blusztajn, Christina L. Williams, Warren H. Meck
Publikováno v:
Brain Research. 1237:153-166
Altered dietary choline availability early in life leads to persistent changes in spatial memory and hippocampal plasticity in adulthood. Developmental programming by early choline nutrition may determine the range of adult choline intake that is opt