Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Melissa J. Bukowski"'
Autor:
Garrett M. Fogo, Anthony R. Anzell, Kathleen J. Maheras, Sarita Raghunayakula, Joseph M. Wider, Katlynn J. Emaus, Timothy D. Bryson, Melissa J. Bukowski, Robert W. Neumar, Karin Przyklenk, Thomas H. Sanderson
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The mitochondrial network continually undergoes events of fission and fusion. Under physiologic conditions, the network is in equilibrium and is characterized by the presence of both elongated and punctate mitochondria. However, this balance
Externí odkaz:
https://doaj.org/article/047536fedba94d2d94407b4fbb6affde
Autor:
Thomas H. Sanderson, Joseph M. Wider, Icksoo Lee, Christian A. Reynolds, Jenney Liu, Bradley Lepore, Reneé Tousignant, Melissa J. Bukowski, Hollie Johnston, Alemu Fite, Sarita Raghunayakula, John Kamholz, Lawrence I. Grossman, Karin Przyklenk, Maik Hüttemann
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract The interaction of light with biological tissue has been successfully utilized for multiple therapeutic purposes. Previous studies have suggested that near infrared light (NIR) enhances the activity of mitochondria by increasing cytochrome c
Externí odkaz:
https://doaj.org/article/d38358554de345238b2771e0cebf73a7
Publikováno v:
Journal of Visualized Experiments.
Autor:
Thomas H Sanderson, Gargi Mahapatra, Petr Pecina, Qinqin Ji, Kebing Yu, Christopher Sinkler, Ashwathy Varughese, Rita Kumar, Melissa J Bukowski, Renee N Tousignant, Arthur R Salomon, Icksoo Lee, Maik Hüttemann
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78627 (2013)
Recent advancements in isolation techniques for cytochrome c (Cytc) have allowed us to discover post-translational modifications of this protein. We previously identified two distinct tyrosine phosphorylated residues on Cytc in mammalian liver and he
Externí odkaz:
https://doaj.org/article/8ddf7ad1911247619c6061b22c6e32a3
Autor:
Garrett M. Fogo, Thomas H. Sanderson, Joseph M. Wider, Sarita Raghunayakula, Karin Przyklenk, Timothy D. Bryson, Melissa J. Bukowski, Kathleen J. Maheras, Katlynn J. Emaus, Anthony R. Anzell, Robert W. Neumar
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
The mitochondrial network continually undergoes events of fission and fusion. Under physiologic conditions, the network is in equilibrium and is characterized by the presence of both elongated and punctate mitochondria. However, this balanced, homeos
Autor:
Lindsay A Pittman, Madison P. Wang, Dlugas Hunter, Melissa J. Bukowski, Charles S. Chung, Alexandra R. Matus, Teresa L. Czeiszperger
Publikováno v:
Circulation Research. 127
Impaired relaxation is a prevalent form of diastolic dysfunction, present in nearly all cases of heart failure and in many asymptomatic adults. To date, there are no accepted treatments for impaired relaxation, despite its biochemical control by calc
Publikováno v:
Circulation Research. 127
Impaired cardiac relaxation is present in nearly all cases of heart failure and possibly in up to 25% of the asymptomatic population. Myocardial relaxation is known to be biochemically modified by the calcium reuptake rate, thin filament calcium sens
Autor:
Charles S. Chung, Alexandra R. Matus, Hunter Dlugas, Melissa J. Bukowski, Teresa L. Czeiszperger, Brianna M. Schick
Publikováno v:
Archives of biochemistry and biophysics
Rapid myocardial relaxation is essential in maintaining cardiac output, and impaired relaxation is an early indicator of diastolic dysfunction. While the biochemical modifiers of relaxation are well known to include calcium handling, thin filament ac
Publikováno v:
Circulation Research. 125
Background: Heart failure and especially heart failure with preserved ejection fraction are significant burdens on health. Intact cardiac trabeculae may reveal functional changes that cannot be seen in other ex vivo (skinned, single molecule) prepara
Autor:
Bradley Lepore, Reneé Tousignant, Thomas H. Sanderson, Joseph M. Wider, Karin Przyklenk, Michelle Jones, Lesley Calo, Rita Kumar, Christian A. Reynolds, Melissa J. Bukowski
Publikováno v:
Molecular and Cellular Neuroscience. 76:68-75
Global brain ischemia/reperfusion induces neuronal damage in vulnerable brain regions, leading to mitochondrial dysfunction and subsequent neuronal death. Induction of neuronal death is mediated by release of cytochrome c (cyt c) from the mitochondri