Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Melissa J Fazzari"'
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285156 (2023)
IntroductionBehavioral-education interventions have the potential to improve quality of life and self-care for patients on hemodialysis (HD) but have not been incorporated into routine clinical practice. The purpose of this pilot study was to determi
Externí odkaz:
https://doaj.org/article/5011adceb28e46a29cd5502ea021e0a6
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss 1 (2022)
Objectives Nearly 20% of pregnancies in patients with SLE result in an adverse pregnancy outcome (APO). We previously developed an APO prediction model using logistic regression and data from Predictors of pRegnancy Outcome: bioMarkers In Antiphospho
Externí odkaz:
https://doaj.org/article/b968b6e6a5c04bda92bee57bd96ff78f
Autor:
Hector Alvarez, Joanna Opalinska, Li Zhou, Davendra Sohal, Melissa J Fazzari, Yiting Yu, Christina Montagna, Elizabeth A Montgomery, Marcia Canto, Kerry B Dunbar, Jean Wang, Juan Carlos Roa, Yongkai Mo, Tushar Bhagat, K H Ramesh, Linda Cannizzaro, J Mollenhauer, Reid F Thompson, Masako Suzuki, Stephen J Meltzer, Ari Melnick, John M Greally, Anirban Maitra, Amit Verma
Publikováno v:
PLoS Genetics, Vol 7, Iss 3, p e1001356 (2011)
Although a combination of genomic and epigenetic alterations are implicated in the multistep transformation of normal squamous esophageal epithelium to Barrett esophagus, dysplasia, and adenocarcinoma, the combinatorial effect of these changes is unk
Externí odkaz:
https://doaj.org/article/6a4dfe7d74b147538ce4d65d3a9a0ab9
Autor:
Marla J Keller, Rebecca P Madan, N Merna Torres, Melissa J Fazzari, Sylvia Cho, Sabah Kalyoussef, Gail Shust, Pedro M M Mesquita, Nicolette Louissaint, Jianmeng Chen, Hillel W Cohen, Erin C Diament, Anna C Lee, Lydia Soto-Torres, Craig W Hendrix, Betsy C Herold
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16475 (2011)
Preclinical and early phase clinical microbicide studies have not consistently predicted the outcome of efficacy trials. To address this gap, candidate biomarkers of microbicide pharmacodynamics and safety were evaluated in a double-blind, placebo-co
Externí odkaz:
https://doaj.org/article/078e4afb56124ed6ba599594a8e87f7d
Autor:
Francine Einstein, Reid F Thompson, Tushar D Bhagat, Melissa J Fazzari, Amit Verma, Nir Barzilai, John M Greally
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8887 (2010)
Perturbations of the intrauterine environment can affect fetal development during critical periods of plasticity, and can increase susceptibility to a number of age-related diseases (e.g., type 2 diabetes mellitus; T2DM), manifesting as late as decad
Externí odkaz:
https://doaj.org/article/8c4ccf624f194da7b14b0109c19b5288
Autor:
Samir Parekh, Joseph A. Sparano, B. Hilda Ye, Melissa J. Fazzari, Shanisha Gordon, Netha Ulahannan, Venu K. Thirukonda, Bing Xia, Pei-Yu Kuo, Violetta Leshchenko, Adam M. Petrich
PDF file - 26K, Simultaneous inhibition of mTOR and AKT pathways is synergistic in Breast cancer cell lines. A-B. Shown here are normalized isobolograms of treatment effects of Rapamycin and MK-2206, in the above cell lines. Proportion of MK-2206 IC5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a36b6b4d4cd668fbd5dc1429771adb4
https://doi.org/10.1158/1078-0432.22444352
https://doi.org/10.1158/1078-0432.22444352
Autor:
Samir Parekh, Joseph A. Sparano, B. Hilda Ye, Melissa J. Fazzari, Shanisha Gordon, Netha Ulahannan, Venu K. Thirukonda, Bing Xia, Pei-Yu Kuo, Violetta Leshchenko, Adam M. Petrich
Purpose: The mTOR pathway is constitutively activated in diffuse large B-cell lymphoma (DLBCL). mTOR inhibitors have activity in DLBCL, although response rates remain low. We evaluated DLBCL cell lines with differential resistance to the mTOR inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247d6a13d19e702f9155961e3d47377d
https://doi.org/10.1158/1078-0432.c.6520139.v1
https://doi.org/10.1158/1078-0432.c.6520139.v1
Autor:
Samir Parekh, Joseph A. Sparano, B. Hilda Ye, Melissa J. Fazzari, Shanisha Gordon, Netha Ulahannan, Venu K. Thirukonda, Bing Xia, Pei-Yu Kuo, Violetta Leshchenko, Adam M. Petrich
PDF file - 24K, The cytotoxic agent Doxorubicin synergizes with Rapamycin, MK-2206 and their combination, in DLBCL cell lines. A-B. 106 cells/ml of two Rapamycin-sensitive cell lines (SUDHL-6 and WSU-NHL) and two Rapamycin-resistant cell lines (SUDHL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3394ed7fec88126457f38b046f7b98ce
https://doi.org/10.1158/1078-0432.22444346.v1
https://doi.org/10.1158/1078-0432.22444346.v1
Autor:
Samir Parekh, Joseph A. Sparano, B. Hilda Ye, Melissa J. Fazzari, Shanisha Gordon, Netha Ulahannan, Venu K. Thirukonda, Bing Xia, Pei-Yu Kuo, Violetta Leshchenko, Adam M. Petrich
PDF file - 121K, A-C. The Rapamycin-resistant cell lines OCI-Ly19 (A) and SUDHL-4 (C) and the Rapamycin-sensitive cell line WSU-NHL (B) were treated for 3 hours and 6 hours with Rapamycin, Nelfinavir, and the combination of the two agents, after whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de1a89657ad6aa40d5c5db8244ca27a
https://doi.org/10.1158/1078-0432.22444355.v1
https://doi.org/10.1158/1078-0432.22444355.v1
Autor:
Samir Parekh, Joseph A. Sparano, B. Hilda Ye, Melissa J. Fazzari, Shanisha Gordon, Netha Ulahannan, Venu K. Thirukonda, Bing Xia, Pei-Yu Kuo, Violetta Leshchenko, Adam M. Petrich
PDF file - 24K, Vinblastine does not synergize with Rapamycin in SU-DHL 4 cell line. A-B. Approximately 106 cells/ml of SUDHL-4 and SUDHL-6 were treated with Rapamycin, Vinblastine, and the combination of both drugs (all doses lower than IC50 for eac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa11f5fefab1d69a1def1821fd580c9
https://doi.org/10.1158/1078-0432.22444349
https://doi.org/10.1158/1078-0432.22444349