Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Melissa J Beck"'
Autor:
Marco A S Baptista, Kuldip D Dave, Mark A Frasier, Todd B Sherer, Melanie Greeley, Melissa J Beck, Julie S Varsho, George A Parker, Cindy Moore, Madeline J Churchill, Charles K Meshul, Brian K Fiske
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80705 (2013)
The objective of this study was to evaluate the pathology time course of the LRRK2 knockout rat model of Parkinson's disease at 1-, 2-, 4-, 8-, 12-, and 16-months of age. The evaluation consisted of histopathology and ultrastructure examination of se
Externí odkaz:
https://doaj.org/article/91c01268d8074bafbcbd4a7729d3872b
Autor:
Kuldip D. Dave, Shehan De Silva, Niketa P. Sheth, Sylvie Ramboz, Melissa J. Beck, Changyu Quang, Robert C. Switzer, III, Syed O. Ahmad, Susan M. Sunkin, Dan Walker, Xiaoxia Cui, Daniel A. Fisher, Aaron M. McCoy, Kevin Gamber, Xiaodong Ding, Matthew S. Goldberg, Stanley A. Benkovic, Meredith Haupt, Marco A.S. Baptista, Brian K. Fiske, Todd B. Sherer, Mark A. Frasier
Publikováno v:
Neurobiology of Disease, Vol 70, Iss , Pp 190-203 (2014)
Recessively inherited loss-of-function mutations in the PTEN-induced putative kinase 1(Pink1), DJ-1 (Park7) and Parkin (Park2) genes are linked to familial cases of early-onset Parkinson's disease (PD). As part of its strategy to provide more tools f
Externí odkaz:
https://doaj.org/article/3b4ee316f83d4fc3bf43bea037f0fae8
Autor:
Michelle L. Pershing, Melissa J. Beck, Jonathan D. Toot, Amera K. Remick, Lisa G. Lanigan, Tracey L. Papenfuss
Publikováno v:
Immunopathology in Toxicology and Drug Development ISBN: 9783319473840
The central and peripheral components of the nervous system exhibit extensive integration and interaction with the immune system in both health and disease. Components of the adaptive immune system touch all systems in the body through the blood and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20252793e8421bb2fa89314b0a7cfd5f
https://doi.org/10.1007/978-3-319-47385-7_5
https://doi.org/10.1007/978-3-319-47385-7_5
Publikováno v:
Journal of Immunotoxicology. 11:376-382
Recently, there has been a renewed interest in the use of the minipig as an alternative to dogs and non-human primates for conducting toxicological assessments in non-rodent species. Since the T-dependent antibody response (TDAR) is one of the most w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e186c4023557e58c72870bc19bdb29c
https://doi.org/10.3109/1547691x.2013.853716
https://doi.org/10.3109/1547691x.2013.853716
Autor:
Philip A. Botham, Merrill O. Tisdel, James M. Mathews, Andrew R. Cook, Kim Z. Travis, Jeffrey C. Wolf, Dan Zadory, Charles B. Breckenridge, Daniel J. Minnema, Mark T. Butt, Melissa J. Beck, Smith Ll, Nicholas C. Sturgess
Publikováno v:
NeuroToxicology. 37:1-14
The pharmacokinetics and neurotoxicity of paraquat dichloride (PQ) were assessed following once weekly administration to C57BL/6J male mice by intraperitoneal injection for 1, 2 or 3 weeks at doses of 10, 15 or 25 mg/kg/week. Approximately 0.3% of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::566f4157863460a61190dea54d046f5d
Autor:
C. J. Bowman, D. G. Stump, D. T. Wilson, J. S. Varsho, Joseph F. Holson, E. L. Padgett, M. D. Nemec, L.E. Kaufman, Melissa J. Beck
Publikováno v:
Developmental and Reproductive Toxicology ISBN: 9780429105234
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb6db95c83960d36fd8e1aba368f95aa
https://doi.org/10.3109/9781841848211-14
https://doi.org/10.3109/9781841848211-14
Autor:
Nicholas C. Sturgess, Mark T. Butt, Philip A. Botham, Kim Z. Travis, Charles B. Breckenridge, Lewis L. Smith, Yun Jiao, Dan Zadory, Richard J. Smeyne, Jeffrey C. Wolf, Andrew R. Cook, Melissa J. Beck, Daniel J. Minnema
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164094 (2016)
PLoS ONE
PLoS ONE
The neurotoxicity of paraquat dichloride (PQ) was assessed in two inbred strains of 9- or 16-week old male C57BL/6 mice housed in two different laboratories and compared to the effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). PQ was ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b54ed58547ce3c04963d90df9abb021
http://europepmc.org/articles/PMC5082881?pdf=render
http://europepmc.org/articles/PMC5082881?pdf=render
Autor:
Adam W. Perala, Michael J. Bartels, Mary Sue Marty, Melissa J. Beck, Daland R. Juberg, Julie K. Passage, M. P. Bell, Kathy A. Brzak, Amanda K. Andrus
Publikováno v:
Regulatory Toxicology and Pharmacology. 63(2):209-224
The effect of age or dose regimen on cholinesterase inhibition (ChEI) from chlorpyrifos (CPF) or CPF–oxon (CPFO) was studied in Crl:CD(SD) rats. Rats were exposed to CPF by gavage in corn oil, rat milk (pups), or in the diet (adults) or to CPFO by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f750116361ca336d92d2946ee85c6d5
Publikováno v:
International Journal of Toxicology. 31:97-126
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::136e967e1822505e2982250a74011f15
https://doi.org/10.1177/1091581811430473
https://doi.org/10.1177/1091581811430473
Autor:
Sylvia Jacobi, Ann Radovsky, Todd Stedeford, Daniel W. Sved, Hanna Silberberg, Les Freshwater, John M. Ariano, Melissa J. Beck, Donald G. Stump, John A. Biesemeier, Marcia Hardy, Nicole R. Myers
Publikováno v:
Birth Defects Research Part B: Developmental and Reproductive Toxicology. 92:17-35
BACKGROUND: Decabromodiphenyl ether (DecaBDE; CASRN 1163-19-5) is a flame retardant used in a variety of manufactured products. A single oral dose of 20.1 mg/kg administered to mice on postnatal day 3 has been reported to alter motor activity at 2, 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc09dde0e661df5cf75656a6c8e42bda
https://doi.org/10.1002/bdrb.20280
https://doi.org/10.1002/bdrb.20280