Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Melissa J, Parsons"'
Autor:
Ashley G. Boice, Karla E. Lopez, Raj K. Pandita, Melissa J. Parsons, Chloe I. Charendoff, Vijay Charaka, Alexandre F. Carisey, Tej K. Pandita, Lisa Bouchier-Hayes
Publikováno v:
Oncogene. 41:3732-3734
Autor:
Vijay Charaka, Alexandre F. Carisey, Ashley Boice, Raj K. Pandita, Tej K. Pandita, Lisa Bouchier-Hayes, Karla E. Lopez, Melissa J. Parsons, Chloé I. Charendoff
Publikováno v:
Oncogene. 41:204-219
In addition to its classical role in apoptosis, accumulating evidence suggests that caspase-2 has non-apoptotic functions, including regulation of cell division. Loss of caspase-2 is known to increase proliferation rates but how caspase-2 is regulati
Autor:
Ashley G, Boice, Karla E, Lopez, Raj K, Pandita, Melissa J, Parsons, Chloe I, Charendoff, Vijay, Charaka, Alexandre F, Carisey, Tej K, Pandita, Lisa, Bouchier-Hayes
Publikováno v:
Oncogene. 41(2)
In addition to its classical role in apoptosis, accumulating evidence suggests that caspase-2 has non-apoptotic functions, including regulation of cell division. Loss of caspase-2 is known to increase proliferation rates but how caspase-2 is regulati
Autor:
Ashley Boice, Tej K. Pandita, Vijay Charaka, Melissa J. Parsons, Lisa Bouchier-Hayes, Karla E. Lopez, Raj K. Pandita, Alexandre F. Carisey, Chloé I. Charendoff
In addition to its classical role in apoptosis, accumulating evidence suggests that caspase-2 has non-apoptotic functions, including regulation of cell division. Loss of caspase-2 is known to increase proliferation rates but how caspase-2 is regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a8919ecab2a9990d3a0b4baf99e8415
https://doi.org/10.1101/2021.03.30.437768
https://doi.org/10.1101/2021.03.30.437768
Autor:
Kiyohiro Ando, Sara R. Fassio, Ruth Thompson, Sheré L. Paris, Andrew Oberst, Brittany A. Rohrman, Peter H. Liu, Richa B. Shah, Chloé I. Charendoff, Lisa Bouchier-Hayes, Melissa J. Parsons, Samuel Sidi
Publikováno v:
Journal of Cell Biology. 216:1795-1810
The PIDDosome (PIDD–RAIDD–caspase-2 complex) is considered to be the primary signaling platform for caspase-2 activation in response to genotoxic stress. Yet studies of PIDD-deficient mice show that caspase-2 activation can proceed in the absence
Autor:
Melissa J. Parsons, Laura L. McCormick, Laura J. Janke, Lisa Bouchier-Hayes, A Howard, Douglas R. Green
Publikováno v:
Cell Death & Differentiation. 20:1174-1182
Despite being the most evolutionarily conserved of the mammalian caspases, little is understood about the cellular function of caspase-2 in normal tissues or what role caspase-2 may have in the progression of human disease. It has been reported that
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1419
The caspase family of proteases includes key regulators of apoptosis and inflammation. The caspases can be divided into two groups, the initiator caspases and the executioner caspases. Initiator caspases include caspase-2, caspase-8, and caspase-9 an
Autor:
Jennifer Martinez, Christopher P. Dillon, Ricardo Weinlich, Gerry Melino, Charles Miller, Melissa J. Parsons
Publikováno v:
EMBO Molecular Medicine
The recent EMBO Molecular Medicine Workshop on Cell Death and Disease was held this past March in the picturesque Alpen ski-town of Obergurgl, Austria. Scientists working on diverse mechanisms and pathways of cell death convened to present and discus
Autor:
Melissa J. Parsons, Douglas R. Green
Publikováno v:
Essays in Biochemistry. 47:99-114
Apoptosis can be thought of as a signalling cascade that results in the death of the cell. Properly executed apoptosis is critically important for both development and homoeostasis of most animals. Accordingly, defects in apoptosis can contribute to
Publikováno v:
Molecular Cell. 37:299-310
B cell CLL/lymphoma-2 (BCL-2) and its relatives comprise the BCL-2 family of proteins, which were originally characterized with respect to their roles in controlling outer mitochondrial membrane integrity and apoptosis. Current observations expand BC