Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Melissa Ilardo"'
Autor:
Melissa Ilardo, Maria C. Ferreira dos Santos, Niels Grote Beverborg, Malini Rajan, M. Abdullah Said, Niek Verweij, Pim Van Der Harst, Peter Van Der Meer, Elizabeth A. Leibold
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
The Bajau Sea Nomads were recently demonstrated to have evolved larger spleens as an adaptation to millennia of a marine foraging lifestyle. The large-spleen phenotype appears to derive from increases in thyroid hormone (TH) production as a result of
Externí odkaz:
https://doaj.org/article/82cd6f5d7fa44447ae70fd353bd0a24e
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140663 (2015)
We propose a metric which can be used to compute the amount of heritable variation enabled by a given dynamical system. A distribution of selection pressures is used such that each pressure selects a particular fixed point via competitive exclusion i
Externí odkaz:
https://doaj.org/article/97f5f9862a634714b0d33246c3436c1c
Autor:
Melissa Ilardo, Natalie Grefenstette, Stephen J. Freeland, Christopher J. Butch, James Stephenson, H. James Cleaves, Richard J. Gillams, Rudrarup Bose, Bakhtiyor Rasulev, Markus Meringer
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
Life uses a common set of 20 coded amino acids (CAAs) to construct proteins. This set was likely canonicalized during early evolution; before this, smaller amino acid sets were gradually expanded as new synthetic, proofreading and coding mechanisms b
Autor:
Richard P. Evershed, Eske Willerslev, Enrico Cappellini, Juergen Cox, Simon Hammann, Lasse Vinner, Morten E. Allentoft, Yucheng Wang, Peter de Barros Damgaard, Martin Sikora, Frido Welker, Mikkel Winther Pedersen, J. Víctor Moreno-Mayar, Julie Dunne, Ana Prohaska, Mélanie Roffet-Salque, Petra Gutenbrunner, Fernando Racimo, Melissa Ilardo
Publikováno v:
Cappellini, E, Prohaska, A, Racimo, F, Welker, F, Pedersen, M W, Allentoft, M E, De Barros Damgaard, P, Gutenbrunner, P, Dunne, J, Hammann, S, Roffet-Salque, M, Ilardo, M, Moreno-Mayar, J V, Wang, Y, Sikora, M, Vinner, L, Cox, J, Evershed, R P & Willerslev, E 2018, ' Ancient Biomolecules and Evolutionary Inference ', Annual Review of Biochemistry, vol. 87, pp. 1029-1060 . https://doi.org/10.1146/annurev-biochem-062917-012002
Cappellini, E, Prohaska, A, Racimo, F, Welker, F, Pedersen, M W, Allentoft, M E, Damgaard, P D B, Gutenbrunner, P, Dunne, J, Hammann, S, Roffet-Salque, M, Ilardo, M, Moreno Mayar, J V, Wang, Y, Sikora, M, Vinner, L, Cox, J, Evershed, R P & Willerslev, E 2018, ' Ancient Biomolecules and Evolutionary Inference ', Annual Review of Biochemistry, vol. 87, 36 . https://doi.org/10.1146/annurev-biochem-062917-012002
Annual Review of Biochemistry
Cappellini, E, Prohaska, A, Racimo, F, Welker, F, Pedersen, M W, Allentoft, M E, Damgaard, P D B, Gutenbrunner, P, Dunne, J, Hammann, S, Roffet-Salque, M, Ilardo, M, Moreno Mayar, J V, Wang, Y, Sikora, M, Vinner, L, Cox, J, Evershed, R P & Willerslev, E 2018, ' Ancient Biomolecules and Evolutionary Inference ', Annual Review of Biochemistry, vol. 87, 36 . https://doi.org/10.1146/annurev-biochem-062917-012002
Annual Review of Biochemistry
Over the last decade, studies of ancient biomolecules-particularly ancient DNA, proteins, and lipids-have revolutionized our understanding of evolutionary history. Though initially fraught with many challenges, the field now stands on firm foundation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b9d39840fe34be40d5d520ba5bd26ff
https://hdl.handle.net/1983/a534342a-a07d-4d2e-b2df-2b6076760272
https://hdl.handle.net/1983/a534342a-a07d-4d2e-b2df-2b6076760272
Autor:
Rasmus Nielsen, Melissa Ilardo
Publikováno v:
Curr Opin Genet Dev
Modern humans inhabit most of earth’s harshest environments and display a wide array of lifestyles. Biological adaptations, in addition to technological innovations, have enabled these geographical and cultural explorations. The study of these adap
Autor:
Melissa Ilardo, Peter de Barros Damgaard, Andaine Seguin-Orlando, Rasmus Nielsen, Fernando Racimo, Inge C.L. van den Munckhof, Jade Cheng, Simon Rasmussen, Eske Willerslev, Martin Sikora, Aaron J. Stern, Mihai G. Netea, Leo A. B. Joosten, Thorfinn Sand Korneliussen, Suhartini Salingkat, Rob ter Horst, Ida Moltke
Publikováno v:
Ilardo, M A, Moltke, I, Korneliussen, T S, Cheng, J, Stern, A J, Racimo, F, de Barros Damgaard, P, Sikora, M, Seguin-Orlando, A, Rasmussen, S, van den Munckhof, I C L, Ter Horst, R, Joosten, L A B, Netea, M G, Salingkat, S, Nielsen, R & Willerslev, E 2018, ' Physiological and Genetic Adaptations to Diving in Sea Nomads ', Cell, vol. 173, no. 3, e15, pp. 569-580 . https://doi.org/10.1016/j.cell.2018.03.054
Cell, 173, 569-580.e15
Cell, 173, 3, pp. 569-580.e15
Cell, 173, 569-580.e15
Cell, 173, 3, pp. 569-580.e15
Understanding the physiology and genetics of human hypoxia tolerance has important medical implications, but this phenomenon has thus far only been investigated in high-altitude human populations. Another system, yet to be explored, is humans who eng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ae256b8c5be185240bd877282c6225
https://orbit.dtu.dk/en/publications/e9e8e881-5185-4e9b-b125-b4df57350482
https://orbit.dtu.dk/en/publications/e9e8e881-5185-4e9b-b125-b4df57350482
Publikováno v:
Scopus-Elsevier
The standard alphabet of the 20 genetically encoded amino acids is considered to have been selected during early evolution from a larger pool of α-amino acids based on its coverage of the chemical space. Chemical space is here defined by charge, siz
Autor:
Muhammad Nadeem, Eske Willerslev, Ashot Margaryan, Martin Sikora, Habib Ahmad, Anders J. Hansen, Numan Fazal, Jill K. Olofsson, Brian E. Hemphill, Inam Ullah, Morten E. Allentoft, Melissa Ilardo, Murad Ali, Anders Buchard
Publikováno v:
Annals of Human Genetics
The ethnic groups that inhabit the mountainous Dir and Swat districts of northern Pakistan are marked by high levels of cultural and phenotypic diversity. To obtain knowledge of the extent of genetic diversity in this region, we investigated Y-chromo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb16e0a0da4bfc967634dfcec789aad6
https://eprints.whiterose.ac.uk/156300/1/InamUllah_etal_AHG.pdf
https://eprints.whiterose.ac.uk/156300/1/InamUllah_etal_AHG.pdf
Publikováno v:
Environmental Microbiology. 13:1138-1152
Ribosomal tag libraries based on DNA and RNA in coral reef sediment from Hawaii show the microbial community to be dominated by the bacterial phyla Proteobacteria, Firmicutes and Actinobacteria, the archaeal order Nitrosopumilales and the uncultivate
Publikováno v:
Scientific Reports
Ilardo, M, Meringer, M, Freeland, S, Rasulev, B & Cleaves, H J II 2015, ' Extraordinarily adaptive properties of the genetically encoded amino acids ', Scientific Reports, vol. 5, 9414 . https://doi.org/10.1038/srep09414
Ilardo, M, Meringer, M, Freeland, S, Rasulev, B & Cleaves, H J II 2015, ' Extraordinarily adaptive properties of the genetically encoded amino acids ', Scientific Reports, vol. 5, 9414 . https://doi.org/10.1038/srep09414
Using novel advances in computational chemistry, we demonstrate that the set of 20 genetically encoded amino acids, used nearly universally to construct all coded terrestrial proteins, has been highly influenced by natural selection. We defined an ad