Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Melissa Hickey"'
Autor:
Hongpeng Jia, Lei Shi, Christine L. Wohlford-Lenane, Lokesh Gakhar, Dwight C. Look, Mark C. Chappell, Paul B. McCray, Ping Tan, Melissa Hickey
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology
Angiotensin-converting enzyme 2 (ACE2) is a terminal carboxypeptidase and the receptor for the SARS and NL63 coronaviruses (CoV). Loss of ACE2 function is implicated in severe acute respiratory syndrome (SARS) pathogenesis, but little is known about
Autor:
Jason Netland, Carmen M. Halabi, Paul B. McCray, Stanley Perlman, Dwight C. Look, Lecia L. Pewe, Melissa Hickey, Lei Shi, Curt D. Sigmund, Hongpeng Jia, David K. Meyerholz, Christine L. Wohlford-Lenane, Patricia A. Kirby, Lori Manzel
Publikováno v:
Journal of Virology
The severe acute respiratory syndrome (SARS), caused by a novel coronavirus (SARS-CoV), resulted in substantial morbidity, mortality, and economic losses during the 2003 epidemic. While SARS-CoV infection has not recurred to a significant extent sinc
Publikováno v:
Molecular Therapy. 13
We are investigating the nonprimate FIV lentiviral vector for gene transfer applications. Although this vector can integrate in transduced cells, little is known about the fate of FIV vector in host cells after infection. Transgenic DNA can persist a
Autor:
Stanley Perlman, Jason Netland, Christine L. Wohlford-Lenane, Melissa Hickey, Dwight C. Look, Paul B. McCray, Hongpeng Jia, Michael Farzan, Lecia L. Pewe, Lei Shi
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9780387262024
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc67832b70bf3201a3e13002493280c6
https://doi.org/10.1007/978-0-387-33012-9_85
https://doi.org/10.1007/978-0-387-33012-9_85
Autor:
Jason Netland, Paul B. McCray, Dwight C. Look, Michael Farzan, Christine L. Wohlford-Lenane, Lecia L. Pewe, Melissa Hickey, Lei Shi, Hongpeng Jia, Stanley Perlman
Publikováno v:
Journal of Virology
Studies of patients with severe acute respiratory syndrome (SARS) demonstrate that the respiratory tract is a major site of SARS-coronavirus (CoV) infection and disease morbidity. We studied host-pathogen interactions using native lung tissue and a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5761debd419ab7517e82688b81bdfb1e
https://europepmc.org/articles/PMC1287568/
https://europepmc.org/articles/PMC1287568/
Autor:
Steven W. Pipe, Patrick L. Sinn, Jessica D. Goreham-Voss, C.P. Chikkanna-Gowda, Melissa Hickey, Litao Xie, Paul B. McCrayJr, Yubin Kang
Publikováno v:
Molecular Therapy. 13:S129
Hemophilia A is an X-linked genetic disorder resulting in deficiencies in coagulation Factor VIII and a risk of sustained bleeding after trauma or injury. Hemophilia A is an attractive candidate for treatment by gene transfer because only partial cor
Publikováno v:
Molecular Therapy. 13:S313
Suboptimal expression from Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) cDNA delivered by viral vectors has, in part, limited the use of gene transfer as a therapy for cystic fibrosis. Previously we described a lentiviral vector develop