Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Melissa Hewitt"'
Autor:
Saina Beitari, Gerard Agbayani, Melissa Hewitt, Diana Duque, Jegarubee Bavananthasivam, Jagdeep K. Sandhu, Bassel Akache, Ita Hadžisejdić, Anh Tran
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract A critical feature of the VSV vector platform is the ability to pseudotype the virus with different glycoproteins from other viruses, thus altering cellular tropism of the recombinant virus. The route of administration is critical in trigger
Externí odkaz:
https://doaj.org/article/e3909f1acd08445bb4da02860f6072a0
Autor:
Saina Beitari, Diana Duque, Jegarubee Bavananthasivam, Melissa Hewitt, Jagdeep K. Sandhu, Ita Hadžisejdić, Anh Tran
Publikováno v:
Virology Journal, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Since SARS-CoV-2 was first reported in late 2019, multiple variations of the original virus have emerged. Each variant harbors accumulations of mutations, particularly within the spike glycoprotein, that are associated with increased viral t
Externí odkaz:
https://doaj.org/article/3cd964127a194d589fdb7520b4d04cee
Autor:
Martin A. Rossotti, Henk van Faassen, Anh T. Tran, Joey Sheff, Jagdeep K. Sandhu, Diana Duque, Melissa Hewitt, Xiaoxue Wen, Jegarubee Bavananthasivam, Saina Beitari, Kevin Matte, Geneviève Laroche, Patrick M. Giguère, Christian Gervais, Matthew Stuible, Julie Guimond, Sylvie Perret, Greg Hussack, Marc-André Langlois, Yves Durocher, Jamshid Tanha
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-19 (2022)
Isolation and extensive characterization of a collection of 37 anti-SARS-CoV-2 spike glycoprotein nanobodies show broad neutralization efficacies in vitro and in vivo in a hamster model of SARS-CoV-2 infection.
Externí odkaz:
https://doaj.org/article/2f48dc9abf474ef9b75e5e6b1b33d3f4
Autor:
M. Lelinneth B. Novilla, Michael C. Goates, Alisha H. Redelfs, Mallory Quenzer, Lynneth Kirsten B. Novilla, Tyler Leffler, Christian A. Holt, Russell B. Doria, Michael T. Dang, Melissa Hewitt, Emma Lind, Elizabeth Prickett, Katelyn Aldridge
Publikováno v:
Vaccines, Vol 11, Iss 5, p 926 (2023)
Ongoing outbreaks of measles threaten its elimination status in the United States. Its resurgence points to lower parental vaccine confidence and local pockets of unvaccinated and undervaccinated individuals. The geographic clustering of hesitancy to
Externí odkaz:
https://doaj.org/article/010e02d11b9d43d2ad089fb97a359808
Autor:
Wandong Zhang, Qing Yan Liu, Arsalan S. Haqqani, Sonia Leclerc, Ziying Liu, François Fauteux, Ewa Baumann, Christie E. Delaney, Dao Ly, Alexandra T. Star, Eric Brunette, Caroline Sodja, Melissa Hewitt, Jagdeep K. Sandhu, Danica B. Stanimirovic
Publikováno v:
Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-17 (2020)
Abstract Receptor-mediated transcytosis (RMT) is a principal pathway for transport of macromolecules essential for brain function across the blood–brain barrier (BBB). Antibodies or peptide ligands which bind RMT receptors are often co-opted for br
Externí odkaz:
https://doaj.org/article/0b303c3f54f44cd1a6df157f40dd7f54
Autor:
Alvaro Yogi, Greg Hussack, Henk van Faassen, Arsalan S. Haqqani, Christie E. Delaney, Eric Brunette, Jagdeep K. Sandhu, Melissa Hewitt, Traian Sulea, Kristin Kemmerich, Danica B. Stanimirovic
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1452 (2022)
The ability of drugs and therapeutic antibodies to reach central nervous system (CNS) targets is greatly diminished by the blood–brain barrier (BBB). Receptor-mediated transcytosis (RMT), which is responsible for the transport of natural protein li
Externí odkaz:
https://doaj.org/article/cebfc66ae2ca43619249a1d974dd42db
Autor:
Miroslava Čuperlović-Culf, Nam H. Khieu, Anuradha Surendra, Melissa Hewitt, Claudie Charlebois, Jagdeep K. Sandhu
Publikováno v:
Metabolites, Vol 10, Iss 3, p 88 (2020)
Glioblastoma (GBM) is one of the most aggressive cancers of the central nervous system. Despite current advances in non-invasive imaging and the advent of novel therapeutic modalities, patient survival remains very low. There is a critical need for t
Externí odkaz:
https://doaj.org/article/8c57e8fbf70f4cf390876cb35c0cba45
Autor:
Shawn P. Murphy, Lakshmi Krishnan, Gerard Agbayani, Kristina Clark, Jagdeep K. Sandhu, Melissa Hewitt, Subash Sad
Publikováno v:
American journal of reproductive immunology (New York, N.Y. : 1989)REFERENCES. 86(4)
PROBLEM Maternal tolerance during pregnancy increases the risk of infection with certain intracellular pathogens. Systemic Salmonella enterica serovar Typhimurium (S.Tm) infection during pregnancy in normally resistant 129X1/SvJ mice leads to severe
Autor:
Sonia Leclerc, Alexandra T. Star, Ziying Liu, Dao Ly, Arsalan S. Haqqani, Caroline Sodja, Qing Yan Liu, Wandong Zhang, Jagdeep K. Sandhu, Eric Brunette, Ewa Baumann, François Fauteux, Danica Stanimirovic, Christie Delaney, Melissa Hewitt
Publikováno v:
Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-17 (2020)
Fluids and Barriers of the CNS
Fluids and Barriers of the CNS
Receptor-mediated transcytosis (RMT) is a principal pathway for transport of macromolecules essential for brain function across the blood-brain barrier (BBB). Antibodies or peptide ligands which bind RMT receptors are often co-opted for brain deliver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9198f63fc7d8f4add55f721bfce74185
https://doi.org/10.1186/s12987-020-00209-0
https://doi.org/10.1186/s12987-020-00209-0
Autor:
Wandong Zhang, Qing Yan Liu, Arsalan S. Haqqani, Sonia Leclerc, Joy Lei, Francois Fauteux, Ewa Baumann, Christie E. Delaney, Dao Ly, Alexandra T. Star, Eric Brunette, Caroline Sodja, Melissa Hewitt, Jagdeep K. Sandhu, Danica B. Stanimirovic
Receptor-mediated transcytosis (RMT) is a principal pathway for transport of macromolecules essential for brain function across the blood-brain barrier (BBB). Antibodies or peptide ligands which bind RMT receptors are often co-opted for brain deliver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fce762c0283940349487f07665063c20
https://doi.org/10.21203/rs.3.rs-16449/v1
https://doi.org/10.21203/rs.3.rs-16449/v1