Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Melissa Estrella"'
Autor:
Melissa Estrella, Christopher A. Teleha, Gary A. Cain, Alfred J. Mical, Andrew M. Blum, Edd R. Holler, James S. Piecara, George C. Emmett, Dean A. Wacker
Publikováno v:
Synthesis. 2005:92-96
Methods for the preparation of (3S)-3-(4-fluorobenzyl)piperidine (2) and its mandelate salt (9) are described. The first generation synthesis started from 3-benzylpiperidone, and required Boc protection of the nitrogen for efficient separation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32a41940b9728638926eda6d6cec68db
https://doi.org/10.1055/s-2004-834903
https://doi.org/10.1055/s-2004-834903
Autor:
Kimberley Solomon, George L. Trainor, Maryanne B. Covington, Melissa Estrella, Robert C. Newton, Joseph B. Santella, Nicole Stowell, Paul S. Watson, Cheryl M. Clark, Jeffrey G. Varnes, Paul Davies, John V. Duncia, Eric A. Wadman, Carl P. Decicco, Gardner Daniel S, Patricia K. Welch, Soo S. Ko, Dean A. Wacker
Publikováno v:
Bioorganicmedicinal chemistry letters. 14(7)
The discovery of novel and selective small molecule antagonists of the CC Chemokine Receptor-3 (CCR3) is presented. Simple conversion from a 4- to 3-benzylpiperidine gave improved selectivity for CCR3 over the serotonin 5HT(2A) receptor. Chiral resol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::752de095193da0d8128da3ea9d091ac1
https://pubmed.ncbi.nlm.nih.gov/15026042
https://pubmed.ncbi.nlm.nih.gov/15026042
Autor:
George Emmett, Gary Cain, Melissa Estrella, Edd Holler, James Piecara, Andrew Blum, Alfred Mical, Christopher Teleha, Dean Wacker
Publikováno v:
Synthesis; 2005, Vol. 2005 Issue 1, p92-96, 5p