Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Melissa E. Munroe"'
Autor:
Eldon R. Jupe, Gerald H. Lushington, Mohan Purushothaman, Fabricio Pautasso, Georg Armstrong, Arif Sorathia, Jessica Crawley, Vijay R. Nadipelli, Bernard Rubin, Ryan Newhardt, Melissa E. Munroe, Brett Adelman
Publikováno v:
BioTech, Vol 12, Iss 4, p 62 (2023)
(1) Objective: Systemic lupus erythematosus (SLE) is a complex disease involving immune dysregulation, episodic flares, and poor quality of life (QOL). For a decentralized digital study of SLE patients, machine learning was used to assess patient-rep
Externí odkaz:
https://doaj.org/article/8ba90c05cea54456b978d5cd7bb61a1a
Autor:
Melissa E. Munroe, Kendra A. Young, Joel M. Guthridge, Diane L. Kamen, Gary S. Gilkeson, Michael H. Weisman, Mariko L. Ishimori, Daniel J. Wallace, David R. Karp, John B. Harley, Jill M. Norris, Judith A. James
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Systemic lupus erythematosus (SLE) is propelled by pathogenic autoantibody (AutoAb) and immune pathway dysregulation. Identifying populations at risk of reaching classified SLE is essential to curtail inflammatory damage. Lupus blood relatives (Rel)
Externí odkaz:
https://doaj.org/article/7621afd0bdc04818b856c37f083c1113
Autor:
Sean Turner, Brent Raisley, Kimberly Roach, Sandra Bajaña, Melissa E. Munroe, Judith A. James, K. Mark Coggeshall, Susan Kovats
Publikováno v:
Microorganisms, Vol 11, Iss 1, p 173 (2023)
Gram-positive bacterial infections are a major cause of organ failure and mortality in sepsis. Cell wall peptidoglycan (PGN) is shed during bacterial replication, and Bacillus anthracis PGN promotes a sepsis-like pathology in baboons. Herein, we dete
Externí odkaz:
https://doaj.org/article/76338808118045a094a816262c2f125b
Autor:
Melissa E. Munroe, Jourdan R. Anderson, Timothy F. Gross, Laura L. Stunz, Gail A. Bishop, Judith A. James
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Systemic lupus erythematosus (SLE) and other autoimmune diseases are propelled by immune dysregulation and pathogenic, disease-specific autoantibodies. Autoimmunity against the lupus autoantigen Sm is associated with cross-reactivity to Epstein-Barr
Externí odkaz:
https://doaj.org/article/cb3059a19d6b475fabedff1c96a36911
Autor:
Joel M. Guthridge, Rufei Lu, Ly Thi-Hai Tran, Cristina Arriens, Teresa Aberle, Stan Kamp, Melissa E. Munroe, Nicolas Dominguez, Timothy Gross, Wade DeJager, Susan R. Macwana, Rebecka L. Bourn, Stephen Apel, Aikaterini Thanou, Hua Chen, Eliza F. Chakravarty, Joan T. Merrill, Judith A. James
Publikováno v:
EClinicalMedicine, Vol 20, Iss , Pp - (2020)
Background: The clinical and pathologic diversity of systemic lupus erythematosus (SLE) hinders diagnosis, management, and treatment development. This study addresses heterogeneity in SLE through comprehensive molecular phenotyping and machine learni
Externí odkaz:
https://doaj.org/article/cb790d3c24634179a0061b64ef7c3855
Autor:
Melissa E. Munroe, Derek Blankenship, Daniele DeFreese, Mohan Purushothaman, Wade DeJager, Susan Macwana, Joel M. Guthridge, Stan Kamp, Nancy Redinger, Teresa Aberle, Eliza F. Chakravarty, Cristina Arriens, Yanfeng Li, Hu Zeng, Kathleen A. McCarthy‐Fruin, Shirley‐Ann Osei‐Onomahm, Uma Thanarajasingam, Judith A. James, Eldon Jupe
Publikováno v:
Arthritis & Rheumatology. 75:723-735
SLE is marked by immune dysregulation linked to varied clinical disease activity. Using a unique longitudinal cohort of SLE patients, this study seeks to identify optimal immune mediators informing an empirically refined Flare Risk Index (FRI) reflec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cddf61fe9a2796062f59d42116602a81
https://doi.org/10.1002/art.42389
https://doi.org/10.1002/art.42389
Autor:
Jill Hahn, Bing Lu, Judith A. James, Laura D. Kubzansky, Xinyi Liu, Candace H. Feldman, Melissa E. Munroe, Elizabeth W. Karlson, Andrea L. Roberts, Susan Malspeis, Cianna Leatherwood, Karen H. Costenbader, Jeffrey A. Sparks
Publikováno v:
Arthritis Care Res (Hoboken)
OBJECTIVE Smoking has been associated with increased systemic lupus erythematosus (SLE) risk, but the biologic basis for this association is unknown. Our objective was to investigate whether women's smoking was positively associated with SLE-associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbac93e01011675c7eb0c4b73f2f8b47
https://doi.org/10.1002/acr.24370
https://doi.org/10.1002/acr.24370
Autor:
Judith A. James, Jeffrey A. Sparks, Elizabeth W. Karlson, Jill Hahn, Cianna Leatherwood, Laura D. Kubzansky, Bing Lu, Candace H. Feldman, Susan Malspeis, Karen H. Costenbader, Melissa E. Munroe, Andrea L. Roberts, Xinyi Liu
Publikováno v:
Lupus
Objectives Moderate alcohol consumption has been associated with decreased systemic lupus erythematosus risk, but the biologic basis for this association is unknown. We aimed to determine whether moderate alcohol consumption was associated with lower
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a96bc988b54fe6d74cb344650a4b18
https://doi.org/10.1177/0961203320929427
https://doi.org/10.1177/0961203320929427
Autor:
Rebecka L. Bourn, Joel M. Guthridge, Stan Kamp, Joan T. Merrill, Krista Bean, Melissa E. Munroe, Judith A. James, Susan R. Macwana, Sudhakar Sridharan, Rufei Lu, Hua Chen
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-4 (2019)
Scientific Reports
Scientific Reports
Systemic lupus erythematosus (SLE) flares elicit progressive organ damage, leading to disability and early mortality. This study evaluated clinical and immunologic factors associated with impending flare in the Biomarkers of Lupus Disease study. Auto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b1548da69a03d3bb4510def2452dbf
http://link.springer.com/article/10.1038/s41598-019-54275-y
http://link.springer.com/article/10.1038/s41598-019-54275-y
Autor:
Virginia Pascual, Karen D. Boyle, Alan N. Baer, Paul J. Utz, Nathalie Franchimont, E. William St. Clair, Teresa Aberle, Eliza F. Chakravarty, Kevin D. Deane, Judith A. James, V. Michael Holers, Lynette Keyes-Elstein, Miles Smith, Rebecka L. Bourn, Andreea Coca, Daniel J. Wallace, Ann L. Parke, Joel M. Guthridge, Kathy L. Sivils, Hua Chen, Ghaith Noaiseh, Tammy O. Utset, Mark C. Genovese, Melissa E. Munroe, Rufei Lu, Krista Bean, James McNamara
Publikováno v:
Rheumatology (Oxford)
ObjectiveTo address heterogeneity complicating primary SS (pSS) clinical trials, research and care by characterizing and clustering patients by their molecular phenotypes.MethodspSS patients met American–European Consensus Group classification crit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bbb7ac2cec44897b6dce08f80384841
https://doi.org/10.1093/rheumatology/kez335
https://doi.org/10.1093/rheumatology/kez335