Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Melissa E. Howard"'
Autor:
Minerva M Carrasquillo, Olivia Belbin, Fanggeng Zou, Mariet Allen, Nilufer Ertekin-Taner, Morad Ansari, Samantha L Wilcox, Mariah R Kashino, Li Ma, Linda H Younkin, Samuel G Younkin, Curtis S Younkin, Toros A Dincman, Melissa E Howard, Chanley C Howell, Chloe M Stanton, Christopher M Watson, Michael Crump, Veronique Vitart, Caroline Hayward, Nicholas D Hastie, Igor Rudan, Harry Campbell, Ozren Polasek, Kristelle Brown, Peter Passmore, David Craig, Bernadette McGuinness, Stephen Todd, Patrick G Kehoe, David M Mann, A David Smith, Helen Beaumont, Donald Warden, Clive Holmes, Reinhard Heun, Heike Kölsch, Noor Kalsheker, V Shane Pankratz, Dennis W Dickson, Neill R Graff-Radford, Ronald C Petersen, Alan F Wright, Steven G Younkin, Kevin Morgan
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8764 (2010)
BACKGROUND:The insulin-degrading enzyme gene (IDE) is a strong functional and positional candidate for late onset Alzheimer's disease (LOAD). METHODOLOGY/PRINCIPAL FINDINGS:We examined conserved regions of IDE and its 10 kb flanks in 269 AD cases and
Externí odkaz:
https://doaj.org/article/30705a34921a465983afe4754bf3908f
Autor:
Melissa E. Howard, Andrew W. Gibson, Alejandro Dieguez-Vazquez, Debra J. Wallace, Artis Klapars, Robert D. Wilson, Jeremy P. Scott, Peter R. Mullens, Andrew D. Gibb, Carl A. Baxter, Jaemoon Lee, Sarah E. Brewer, Stephen P. Keen, Ed Cleator, Nadine Bremeyer, Anthony Alorati, Kevin R. Campos, Matthew L. Maddess, Joseph J. Lynch, Jing Li
Publikováno v:
Organic Process Research & Development. 18:528-538
The development and execution of a practical asymmetric synthesis of the estrogen receptor beta selective agonist (8R,10aS)-6-(trifluoromethyl)-8,9,10,11-tetrahydro-8,10a-methanocyclohepta[1,2]indeno[4,5-d][1,2,3]triazol-7(3H)-one is described. The o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fdefbcc65171430752e7a0100c3ac289
https://doi.org/10.1021/op5000489
https://doi.org/10.1021/op5000489
Autor:
Debra J. Wallace, Paul D. O’Shea, Carmela Molinaro, Paul G. Bulger, Stephen Lau, Melissa E. Howard, Danny Gauvreau, Birgit Kosjek, Ernest E. Lee
Publikováno v:
The Journal of Organic Chemistry. 77:2299-2309
In this paper, we report the development of different synthetic routes to MK-7246 (1) designed by the Process Chemistry group. The syntheses were initially designed as an enabling tool for Medicinal Chemistry colleagues in order to rapidly explore st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a169ae2009a6fd29d54586708b512e37
https://doi.org/10.1021/jo202620r
https://doi.org/10.1021/jo202620r