Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Melissa E Munroe"'
Autor:
Melissa E Munroe, Nathan Pezant, Michael A Brown, Dustin A Fife, Joel M Guthridge, Jennifer A Kelly, Graham Wiley, Patrick M Gaffney, Judith A James, Courtney G Montgomery
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171193 (2017)
Antiviral defenses are inappropriately activated in systemic lupus erythematosus (SLE) and association between SLE and the antiviral helicase gene, IFIH1, is well established. We sought to extend the previously reported association of pathogenic solu
Externí odkaz:
https://doaj.org/article/b0a35b4198304640bf25761b2bf70b96
Autor:
Kaval Kaur, Nai-Ying Zheng, Kenneth Smith, Min Huang, Lie Li, Noel T Pauli, Carole J Henry Dunand, Jane-Hwei Lee, Michael Morrissey, Yixuan Wu, Michelle L Joachims, Melissa E Munroe, Denise Lau, Xinyan Qu, Florian Krammer, Jens Wrammert, Peter Palese, Rafi Ahmed, Judith A James, Patrick C Wilson
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125618 (2015)
Breakdown of B cell tolerance is a cardinal feature of systemic lupus erythematosus (SLE). Increased numbers of autoreactive mature naïve B cells have been described in SLE patients and autoantibodies have been shown to arise from autoreactive and n
Externí odkaz:
https://doaj.org/article/af56636f00884a63a7d502d8b7d8e932
Autor:
Eldon R. Jupe, Gerald H. Lushington, Mohan Purushothaman, Fabricio Pautasso, Georg Armstrong, Arif Sorathia, Jessica Crawley, Vijay R. Nadipelli, Bernard Rubin, Ryan Newhardt, Melissa E. Munroe, Brett Adelman
Publikováno v:
BioTech, Vol 12, Iss 4, p 62 (2023)
(1) Objective: Systemic lupus erythematosus (SLE) is a complex disease involving immune dysregulation, episodic flares, and poor quality of life (QOL). For a decentralized digital study of SLE patients, machine learning was used to assess patient-rep
Externí odkaz:
https://doaj.org/article/8ba90c05cea54456b978d5cd7bb61a1a
Autor:
Melissa E. Munroe, Kendra A. Young, Joel M. Guthridge, Diane L. Kamen, Gary S. Gilkeson, Michael H. Weisman, Mariko L. Ishimori, Daniel J. Wallace, David R. Karp, John B. Harley, Jill M. Norris, Judith A. James
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Systemic lupus erythematosus (SLE) is propelled by pathogenic autoantibody (AutoAb) and immune pathway dysregulation. Identifying populations at risk of reaching classified SLE is essential to curtail inflammatory damage. Lupus blood relatives (Rel)
Externí odkaz:
https://doaj.org/article/7621afd0bdc04818b856c37f083c1113
Autor:
Sean Turner, Brent Raisley, Kimberly Roach, Sandra Bajaña, Melissa E. Munroe, Judith A. James, K. Mark Coggeshall, Susan Kovats
Publikováno v:
Microorganisms, Vol 11, Iss 1, p 173 (2023)
Gram-positive bacterial infections are a major cause of organ failure and mortality in sepsis. Cell wall peptidoglycan (PGN) is shed during bacterial replication, and Bacillus anthracis PGN promotes a sepsis-like pathology in baboons. Herein, we dete
Externí odkaz:
https://doaj.org/article/76338808118045a094a816262c2f125b
Autor:
Melissa E. Munroe, Jourdan R. Anderson, Timothy F. Gross, Laura L. Stunz, Gail A. Bishop, Judith A. James
Publikováno v:
Frontiers in Immunology, Vol 11 (2021)
Systemic lupus erythematosus (SLE) and other autoimmune diseases are propelled by immune dysregulation and pathogenic, disease-specific autoantibodies. Autoimmunity against the lupus autoantigen Sm is associated with cross-reactivity to Epstein-Barr
Externí odkaz:
https://doaj.org/article/cb3059a19d6b475fabedff1c96a36911
Autor:
Melissa E. Munroe, Derek Blankenship, Daniele DeFreese, Mohan Purushothaman, Wade DeJager, Susan Macwana, Joel M. Guthridge, Stan Kamp, Nancy Redinger, Teresa Aberle, Eliza F. Chakravarty, Cristina Arriens, Yanfeng Li, Hu Zeng, Kathleen A. McCarthy‐Fruin, Shirley‐Ann Osei‐Onomahm, Uma Thanarajasingam, Judith A. James, Eldon Jupe
Publikováno v:
Arthritis & Rheumatology. 75:723-735
SLE is marked by immune dysregulation linked to varied clinical disease activity. Using a unique longitudinal cohort of SLE patients, this study seeks to identify optimal immune mediators informing an empirically refined Flare Risk Index (FRI) reflec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cddf61fe9a2796062f59d42116602a81
https://doi.org/10.1002/art.42389
https://doi.org/10.1002/art.42389
Autor:
Jill Hahn, Bing Lu, Judith A. James, Laura D. Kubzansky, Xinyi Liu, Candace H. Feldman, Melissa E. Munroe, Elizabeth W. Karlson, Andrea L. Roberts, Susan Malspeis, Cianna Leatherwood, Karen H. Costenbader, Jeffrey A. Sparks
Publikováno v:
Arthritis Care Res (Hoboken)
OBJECTIVE Smoking has been associated with increased systemic lupus erythematosus (SLE) risk, but the biologic basis for this association is unknown. Our objective was to investigate whether women's smoking was positively associated with SLE-associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbac93e01011675c7eb0c4b73f2f8b47
https://doi.org/10.1002/acr.24370
https://doi.org/10.1002/acr.24370
Autor:
Judith A. James, Jeffrey A. Sparks, Elizabeth W. Karlson, Jill Hahn, Cianna Leatherwood, Laura D. Kubzansky, Bing Lu, Candace H. Feldman, Susan Malspeis, Karen H. Costenbader, Melissa E. Munroe, Andrea L. Roberts, Xinyi Liu
Publikováno v:
Lupus
Objectives Moderate alcohol consumption has been associated with decreased systemic lupus erythematosus risk, but the biologic basis for this association is unknown. We aimed to determine whether moderate alcohol consumption was associated with lower
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98a96bc988b54fe6d74cb344650a4b18
https://doi.org/10.1177/0961203320929427
https://doi.org/10.1177/0961203320929427
Autor:
Rebecka L. Bourn, Joel M. Guthridge, Stan Kamp, Joan T. Merrill, Krista Bean, Melissa E. Munroe, Judith A. James, Susan R. Macwana, Sudhakar Sridharan, Rufei Lu, Hua Chen
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-4 (2019)
Scientific Reports
Scientific Reports
Systemic lupus erythematosus (SLE) flares elicit progressive organ damage, leading to disability and early mortality. This study evaluated clinical and immunologic factors associated with impending flare in the Biomarkers of Lupus Disease study. Auto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b1548da69a03d3bb4510def2452dbf
http://link.springer.com/article/10.1038/s41598-019-54275-y
http://link.springer.com/article/10.1038/s41598-019-54275-y