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Autor:
Melissa Diagana, Ying Zhang, Augustine Lin, Nicole Belmar, Melinda Meier, Kimvan Tran, Florence Boissiere, Dirk Brockstedt, Yawen Chiang, Adrienne Yang
Publikováno v:
Molecular Therapy. 6(5):627-636
Gene therapy for cancer using suicide genes such as the herpes simplex virus thymidine kinase gene (HSVtk) has been explored extensively in preclinical and clinical studies. We have improved the use of HSVtk by combining it with two cytokine genes en