Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Melissa Degardin"'
Autor:
Martha Hale, Dariush Ajami, Melissa Degardin, Daniel Angus Ryan, Mitra Rebek, Michael D. Cameron, Julius Rebek, Kamal U. Saikh, Shahabuddin Alam, Teri L. Kissner
Publikováno v:
Chemical biologydrug design. 90(6)
Small molecules were developed to attenuate proinflammatory cytokines resulting from activation of MyD88-mediated toll-like receptor (TLR) signaling by Francisella tularensis. Fifty-three tripeptide derivatives were synthesized to mimic a key BB-loop
Autor:
Floyd E. Romesberg, Kirandeep Dhami, Thomas Lavergne, Denis A. Malyshev, Lingjun Li, Phillip Ordoukhanian, Melissa Degardin
We synthesized a panel of unnatural base pairs whose pairing depends on hydrophobic and packing forces and identify dTPT3-dNaM, which is PCR amplified with a natural base pair-like efficiency and fidelity. In addition, the dTPT3 scaffold is uniquely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b573ceebc46d0c331587acf6b9c245f
https://europepmc.org/articles/PMC3979842/
https://europepmc.org/articles/PMC3979842/
Autor:
Kirandeep Dhami, Thomas Lavergne, Floyd E. Romesberg, Henry T. Quach, Phillip Ordoukhanian, Denis A. Malyshev, Melissa Degardin
As part of an ongoing effort to expand the genetic alphabet for in vitro and eventually in vivo applications, we have synthesized a wide variety of predominantly hydrophobic unnatural base pairs exemplified by d5SICS-dMMO2 and d5SICS-dNaM. When incor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ad0381d29d7ca4c19bb0a253092de56
https://europepmc.org/articles/PMC3690937/
https://europepmc.org/articles/PMC3690937/
Autor:
Zhao-Hui Jin, Atsushi B. Tsuji, Mélissa Degardin, Pascal Dumy, Didier Boturyn, Tatsuya Higashi
Publikováno v:
Cells, Vol 11, Iss 21, p 3499 (2022)
pH (low) insertion peptides (pHLIPs) have been developed for cancer imaging and therapy targeting the acidic extracellular microenvironment. However, the characteristics of intratumoral distribution (ITD) of pHLIPs are not yet fully understood. This
Externí odkaz:
https://doaj.org/article/5d0af2a4a582471eb1cfafa9f71406c9
Publikováno v:
Chemical Communications. 49:4842
We describe the synthesis and photochemical behavior of open-ended container modules connected by a 4,4'-azobiphenyl spacer. Both trans and cis azo configurations of the host can be accessed and their binding of guest molecules was characterized by N
Publikováno v:
Chemical Communications. 48:11850
The synthesis of deep cavitands with functionalized acetals as a fourth-wall is described. Recognition properties and stabilities of the complexes of two representative cavitands with aliphatic, aromatic, carbocyclic and adamantane guests were evalua
Autor:
Zhao-Hui Jin, Atsushi B. Tsuji, Mélissa Degardin, Aya Sugyo, Yukie Yoshii, Kotaro Nagatsu, Ming-Rong Zhang, Yasuhisa Fujibayashi, Pascal Dumy, Didier Boturyn, Tatsuya Higashi
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Background The present study proposed a new concept for targeted radionuclide therapy (TRT) to improve the intratumoral distribution of radioactivity using two different radiopharmaceuticals. We examined the efficacy of a combination of a te
Externí odkaz:
https://doaj.org/article/8b0bf5d5939249e6adaaf9de3eb3dad2