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pro vyhledávání: '"Melissa D. LaJevic"'
Publikováno v:
Immunology. 132:197-208
The catecholamine norepinephrine (NE) stimulates T lymphocytes through a beta-adrenergic receptor (βAR)/adenylyl cyclase (AC)/cyclic AMP (cAMP)/protein kinase A (PKA) pathway, leading to altered cell responsiveness and apoptosis. p38 Mitogen-activat
Autor:
Donald A. Chambers, Sujatha P. Koduvayur, Veronique Caffrey, Melissa D. LaJevic, Rhonna L. Cohen
Publikováno v:
Brain, Behavior, and Immunity. 24:1078-1088
Thy-1 is a cell surface protein important in immunologic and neurologic processes, including T cell activation and proliferation, and neuronal outgrowth. In murine thymocytes, Thy-1 is downregulated in response to norepinephrine (NE) through posttran
Publikováno v:
The Journal of Immunology. 182:136.15-136.15
p38 MAPK is an important intracellular signaling mediator for a variety of cellular and environmental stressors and plays a role in cell survival, apoptosis, and inflammation. Previously, our lab has shown that norepinephrine (NE) treatment of S49 T
Publikováno v:
The Journal of Immunology. 182:136.13-136.13
Under conditions of psychological stress, release of the catecholamine, norepinephrine (NE), by sympathetic nerves has been reported. We described Thy1 mRNA regulation via a NE-ß2 adrenergic receptor-cAMP-PKA dependent pathway (NE pathway) in murine