Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Melissa D. Chengalroyen"'
Autor:
Melissa D. Chengalroyen, Carolina Mehaffy, Megan Lucas, Niel Bauer, Mabule L. Raphela, Nurudeen Oketade, Digby F. Warner, Deborah A. Lewinsohn, David M. Lewinsohn, Karen M. Dobos, Valerie Mizrahi
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
ABSTRACT Riboflavin (vitamin B2) is the precursor of the flavin coenzymes, FAD and FMN, which play a central role in cellular redox metabolism. While humans must obtain riboflavin from dietary sources, certain microbes, including Mycobacterium tuberc
Externí odkaz:
https://doaj.org/article/9e0d64474c2449c7bd3876da27d5decc
Autor:
Melissa D. Chengalroyen
Publikováno v:
Pathogens, Vol 12, Iss 11, p 1343 (2023)
Mucosal-associated invariant T (MAIT) cells are a distinct population of non-conventional T cells that have been preserved through evolution and possess properties of both innate and adaptive immune cells. They are activated through the recognition o
Externí odkaz:
https://doaj.org/article/9319104100854458b9fdf97f8b890f32
Autor:
Melissa D. Chengalroyen, Germar M. Beukes, Kennedy Otwombe, Bhavna G. Gordhan, Neil Martinson, Bavesh Kana
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Tuberculosis (TB) infected individuals harbor a heterogenous population of differentially culturable tubercle bacilli (DCTB). Herein, we describe how DCTB assays using culture filtrate either containing or deficient in resuscitation promoting factors
Externí odkaz:
https://doaj.org/article/5f74d09d5ad24715a72df06cb508fc34
Autor:
Melissa D. Chengalroyen, Audrey Jordaan, Ronnett Seldon, Thomas Ioerger, Scott G. Franzblau, Mohamed Nasr, Digby F. Warner, Valerie Mizrahi
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Compounds with novel modes of action are urgently needed to develop effective combination therapies for the treatment of tuberculosis. In this study, a series of compounds was evaluated for activity against replicating Mycobacterium tuberculosis and
Externí odkaz:
https://doaj.org/article/5d51bc9be63449abbabb4eac3d227c42
Autor:
Melissa D. Chengalroyen, Mandy K. Mason, Alessandro Borsellini, Raffaella Tassoni, Garth L. Abrahams, Sasha Lynch, Yong-Mo Ahn, Jon Ambler, Katherine Young, Brendan M. Crowley, David B. Olsen, Digby F. Warner, Clifton E. Barry III, Helena I. M. Boshoff, Meindert H. Lamers, Valerie Mizrahi
Publikováno v:
ACS Infectious Diseases, 8(3), 612-625. AMER CHEMICAL SOC
Natural products provide a rich source of potential antimicrobials for treating infectious diseases for which drug resistance has emerged. Foremost among these diseases is tuberculosis. Assessment of the antimycobacterial activity of nargenicin, a na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3fb2ed0c508f40ee8c1ebeb5a93f63a
https://hdl.handle.net/1887/3514350
https://hdl.handle.net/1887/3514350
Autor:
Melissa D, Chengalroyen, Mandy K, Mason, Alessandro, Borsellini, Raffaella, Tassoni, Garth L, Abrahams, Sasha, Lynch, Yong-Mo, Ahn, Jon, Ambler, Katherine, Young, Brendan M, Crowley, David B, Olsen, Digby F, Warner, Clifton E, Barry Iii, Helena I M, Boshoff, Meindert H, Lamers, Valerie, Mizrahi
Publikováno v:
ACS infectious diseases. 8(3)
Natural products provide a rich source of potential antimicrobials for treating infectious diseases for which drug resistance has emerged. Foremost among these diseases is tuberculosis. Assessment of the antimycobacterial activity of nargenicin, a na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b64455ca74c05abd995614158f98e672
https://pubmed.ncbi.nlm.nih.gov/35143160
https://pubmed.ncbi.nlm.nih.gov/35143160
Autor:
Digby F. Warner, Melissa D. Chengalroyen, Sasha L. Lynch, Katherine Young, Mandy K. Mason, Brendan M. Crowley, Raffaella Tassoni, Valerie Mizrahi, David B. Olsen, Clifton E. Barry, Alessandro Borsellini, Garth L. Abrahams, Yong-Mo Ahn, Jon Ambler, Helena I. Boshoff, Meindert H Lamers
SUMMARYNatural products provide a rich source of potential antimicrobials for use in treating infectious diseases for which drug resistance has emerged. Foremost among these is tuberculosis. Assessment of the antimycobacterial activity of nargenicin,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2413ae812a6154daa5b1ef262f9a95ec
https://doi.org/10.1101/2021.10.27.466036
https://doi.org/10.1101/2021.10.27.466036
Autor:
Suraj P. Parihar, Bryan D. Bryson, Hlumani Ndlovu, Mohau S. Makatsa, Sabelo Hadebe, Anastasia Koch, Melissa D. Chengalroyen, Mohlopheni J. Marakalala, Reto Guler, Kehilwe C. Nakedi, Muki Shey
Publikováno v:
Gates Open Research
Tuberculosis, caused by the highly infectious Mycobacterium tuberculosis, remains a leading cause of death worldwide, with an estimated 1.6 million associated deaths reported in 2017. In South Africa, an estimated 322,000 people were infected with TB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14603150492120ad599d1b42833f3500
https://doi.org/10.12688/gatesopenres.13035.1
https://doi.org/10.12688/gatesopenres.13035.1