Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Melissa Chont"'
Autor:
John W. Burns, Asokumar Buvanendran, Dima Qu'd, Stephen Bruehl, David A. Edwards, Kelli F. Koltyn, Rajnish K. Gupta, Melissa Chont, Yung Hsuan Wu, Amanda L. Stone
Publikováno v:
Pain
Aerobic exercise is believed to be an effective chronic low back pain (CLBP) intervention, although its mechanisms remain largely untested. This study evaluated whether endogenous opioid (EO) mechanisms contributed to the analgesic effects of an aero
Autor:
Stephen Bruehl, Melissa Chont, Mary Kennedy, John W. Burns, David A. Edwards, Cassandra Palmer, Amanda L. Stone, Asokumar Buvanendran, Rajnish K. Gupta
Publikováno v:
Regional Anesthesia & Pain Medicine. 44:92-99
Background and objectivesTo expand the evidence base needed to enable personalized pain medicine, we evaluated whether self-reported cumulative exposure to medical opioids and subjective responses on first opioid use predicted responses to placebo-co
Autor:
Asokumar Buvanendran, Stephen Bruehl, John W. Burns, Melissa Chont, Yung Hsuan Wu, David A. Edwards, Kelli F. Koltyn, Amanda L. Stone, Rajnish K. Gupta
Publikováno v:
Pain
We tested whether aerobic exercise training altered morphine analgesic responses or reduced morphine dosages necessary for adequate analgesia. Patients with chronic back pain were randomized to an 18-session aerobic exercise intervention (n = 38) or
Autor:
John W. Burns, Stephen Bruehl, Christopher R. France, Erik Schuster, Daria Orlowska, Asokumar Buvanendran, Melissa Chont, Rajnish K. Gupta
Publikováno v:
Pain. 158:391-399
Use of opioid analgesics for management of chronic nonmalignant pain has become common, yet there are presently no well-validated predictors of optimal opioid analgesic efficacy. We examined whether psychosocial factors (eg, depressive symptoms) pred
Autor:
Melissa Chont, John W. Burns, Stephen Bruehl, Helen J Burgess, Rajnish K. Gupta, Asokumar Buvanendran, Mary Kennedy
Publikováno v:
Clin J Pain
Objectives Sleep disturbance and chronic pain are related. The present study evaluated both direct and indirect (mediated) pathways through which sleep disturbance might be related to chronic pain intensity and function. Methods In total, 87 individu
Autor:
David A. Edwards, Lawrence J. Marnett, Sachin Patel, John W. Burns, Stephen Bruehl, Melissa Chont, Kelli F. Koltyn, Philip J. Kingsley, Amanda J. Morgan, Amanda L. Stone, Asokumar Buvanendran, Rajnish K. Gupta
We sought to replicate previous findings that low endogenous opioid (EO) function predicts greater morphine analgesia and extended these findings by examining whether circulating endocannabinoids and related lipids moderate EO-related predictive effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ea693c72e9e02786db825cbbd71e92
https://europepmc.org/articles/PMC6377294/
https://europepmc.org/articles/PMC6377294/
Autor:
Christopher R. France, John W. Burns, Rajnish K. Gupta, Asokumar Buvanendran, Melissa Chont, Erik Schuster, Daria Orlowska, Stephen Bruehl
Publikováno v:
Annals of Behavioral Medicine. 50:497-505
Recent studies suggest that participant expectations influence pain ratings during conditioned pain modulation testing. The present study extends this work by examining expectancy effects among individuals with and without chronic back pain after adm
Endogenous Opioid Function and Responses to Morphine: The Moderating Effects of Anger Expressiveness
Autor:
John W. Burns, Stephen Bruehl, Christopher R. France, Erik Schuster, Daria Orlowska, Melissa Chont, Rajnish K. Gupta, Asokumar Buvanendran
Long-term use of opioid analgesics may be ineffective or associated with significant negative side effects for some people. At present, there is no sound method of identifying optimal opioid candidates. Individuals with chronic low back pain (n = 89)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74743fe425b4a1e593792f19e811dc37
https://europepmc.org/articles/PMC5729586/
https://europepmc.org/articles/PMC5729586/
Autor:
Stephen Bruehl, John W. Burns, Rajnish Gupta, Asokumar Buvanendran, Melissa Chont, Daria Orlowska, Erik Schuster, Christopher R. France
OBJECTIVES Clinically feasible predictors of opioid analgesic responses for use in precision pain medicine protocols are needed. This study evaluated whether resting plasma β-endorphin (BE) levels predicted responses to an opioid analgesic, and whet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79dab035617116b473f4795d608d3552
https://europepmc.org/articles/PMC5107361/
https://europepmc.org/articles/PMC5107361/
Autor:
Stephen Bruehl, John W. Burns, Rajnish Gupta, Asokumar Buvanendran, Melissa Chont, Erik Schuster, Christopher R. France
Publikováno v:
Regional Anesthesia and Pain Medicine. 39:120-125
Factors underlying differential responsiveness to opioid analgesic medications used in chronic pain management are poorly understood. We tested whether individual differences in endogenous opioid inhibition of chronic low-back pain were associated wi