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Autor:
Bruna Menezes, Eshita Khera, Melissa Calopiz, Michael D. Smith, Michelle L. Ganno, Cornelius Cilliers, Adnan O. Abu-Yousif, Jennifer J. Linderman, Greg M. Thurber
Publikováno v:
The AAPS journal. 24(6)
The development of new antibody-drug conjugates (ADCs) has led to the approval of 7 ADCs by the FDA in 4 years. Given the impact of intratumoral distribution on efficacy of these therapeutics, coadministration of unconjugated antibody with ADC has be