Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Melissa C. Hardstone"'
Autor:
Laura K Sirot, Melissa C Hardstone, Michelle E H Helinski, José M C Ribeiro, Mari Kimura, Prasit Deewatthanawong, Mariana F Wolfner, Laura C Harrington
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 3, p e989 (2011)
No commercially licensed vaccine or treatment is available for dengue fever, a potentially lethal infection that impacts millions of lives annually. New tools that target mosquito control may reduce vector populations and break the cycle of dengue tr
Externí odkaz:
https://doaj.org/article/d0e0dd8b947e429f8bd7c4d8c252f60b
Autor:
Si Hyeock Lee, Kyong Sup Yoon, J. Marshall Clark, Il-Kwon Park, Young-Joon Ahn, Melissa C. Hardstone, Laura C. Harrington, Junheon Kim, Joseph P. Strycharz
Publikováno v:
Pest Management Science. 71:842-849
BACKGROUND: Pyrethroids are the insecticides of choice when exposure to humans is likely, such as occurs in vector and public-health-related control programs. Unfortunately, the pyrethroids share a common resistance mechanism with dichlorodiphenyltri
Autor:
Frank D. Rinkevich, Jeffrey G. Scott, Melissa C. Hardstone, Tomás A. Lazo, Cheryl A. Leichter
Publikováno v:
Pesticide Biochemistry and Physiology. 105:161-168
Resistance to pyrethroids is caused by mutations in the voltage-sensitive sodium channel (Vssc) and enhanced metabolic detoxification by CYP6D1 in the house fly, Musca domestica. We investigated if there was a fitness cost associated with resistance
Publikováno v:
Journal of Medical Entomology. 49:277-285
The spread of exotic mosquito species into new environments can introduce shifts in mosquito populations and potentially alter public health risks to mosquito-borne diseases. The successful establishment of exotic species may occur due to their compe
Autor:
Melissa C. Hardstone, Jeffrey G. Scott
Publikováno v:
Pest Management Science. 66:1171-1180
BACKGROUND: Honey bees (Apis mellifera L.) are among the most important pollinators in natural and agricultural settings. They commonly encounter insecticides, and the effects of insecticides on honey bees have been frequently noted. It has been sugg
Publikováno v:
Insect Molecular Biology. 19:717-726
Previous studies on a strain of Culex pipiens quinquefasciatus from Saudi Arabia indicated permethrin resistance was a result of cytochrome P450 mediated detoxification and kdr. The P450 detoxification was found to be larval specific and associated w
Autor:
Melissa C. Hardstone, Jeffrey G. Scott
Publikováno v:
Pesticide Biochemistry and Physiology. 97:123-128
Insecticide resistance is an ever escalating problem worldwide in many pest populations and numerous cases of insecticide resistance are polygenic. Therefore, it is important to investigate the types of interactions that occur between insecticide res
Publikováno v:
Journal of Evolutionary Biology. 22:416-423
Epistasis is the nonadditive interaction between different loci which contribute to a phenotype. Epistasis between independent loci conferring insecticide resistance is important to investigate as this phenomenon can shape the rate that resistance ev
Autor:
Laura C. Harrington, Jeffrey G. Scott, Shinji Kasai, Melissa C. Hardstone, Takashi Tomita, Cheryl A. Leichter
Publikováno v:
Pesticide Biochemistry and Physiology. 89:175-184
The cytochrome P450-dependent monooxygenases (P450s) are an important enzymatic system that metabolizes xenobiotics (e.g., pesticides), as well as endogenous compounds (e.g., hormones). P450-mediated metabolism can result in detoxification of insecti
Publikováno v:
Pesticide Biochemistry and Physiology. 84:236-242
Cytochrome P450-dependent monooxygenases are important in the activation and detoxification of numerous insecticides. In this study, a Drosophila melanogaster Cyp6d4 null mutant was used to determine the role of this P450 in insecticide metabolism. T