Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Melissa Brazier-Hicks"'
Autor:
Maria Font-Farre, Daniel Brown, Reka Toth, Chidambareswaren Mahadevan, Melissa Brazier-Hicks, Kyoko Morimoto, Farnusch Kaschani, John Sinclair, Richard Dale, Samantha Hall, Melloney Morris, Markus Kaiser, Aaron T. Wright, Jonathan Burton, Renier A. L. van der Hoorn
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Eukaryotes produce a large number of cytochrome P450s that mediate the synthesis and degradation of diverse endogenous and exogenous metabolites. Yet, most of these P450s are uncharacterized and global tools to study these challenging, membr
Externí odkaz:
https://doaj.org/article/7d62dcaa4bcb49e79c3ba9092591fd25
Autor:
Sara Franco-Ortega, Alina Goldberg-Cavalleri, Andrew Walker, Melissa Brazier-Hicks, Nawaporn Onkokesung, Robert Edwards
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
Non-target site resistance (NTSR) to herbicides in black-grass (Alopecurus myosuroides) results in enhanced tolerance to multiple chemistries and is widespread in Northern Europe. To help define the underpinning mechanisms of resistance, global trans
Externí odkaz:
https://doaj.org/article/d341ebbdb9674be5a479387d1f85d527
Autor:
Melissa Brazier-Hicks, Sara Franco-Ortega, Philip Watson, Blandine Rougemont, Jonathan Cohn, Richard Dale, Tim R. Hawkes, Alina Goldberg-Cavalleri, Nawaporn Onkokesung, Robert Edwards
Publikováno v:
ACS Omega. 7:17416-17431
Safeners such as metcamifen and benoxacor are widely used in maize to enhance the selectivity of herbicides through the induction of key detoxifying enzymes, notably cytochrome P450 monooxygenases (CYPs). Using a combination of transcriptomics, prote
Autor:
Nawaporn Onkokesung, Melissa Brazier-Hicks, Catherine Tetard-Jones, Andrew Bentham, Robert Edwards
Publikováno v:
Journal of biotechnology. 358
The growth of resistance to multiple herbicides in grass weeds is a major threat to global cereal production and in the UK, is epitomized by the loss of control of blackgrass (Alopecurus myosuroides), causing losses in winter wheat production equatin
Autor:
Melissa Brazier-Hicks, Maria Schwarz, Glynn Mitchell, Robert Edwards, Ian Cummins, David J. Wortley, Patrick G. Steel, Hannah E. Straker, David John Hughes, Rebecca Florence Mary Eno, Christopher R. Coxon, Ehmke Pohl, Jenny Moore, Nawaporn Onkokesung, Stefanie Freitag-Pohl
Publikováno v:
Organic & Biomolecular Chemistry
Organic & Biomolecular Chemistry, 2021, Vol.19(42), pp.9211-9222 [Peer Reviewed Journal]
Schwarz, M, Eno, R F M, Freitag-Pohl, S, Coxon, C R, Straker, H E, Wortley, D J, Hughes, D J, Mitchell, G, Moore, J, Cummins, I, Onkokesung, N, Brazier-Hicks, M, Edwards, R, Pohl, E & Steel, P G 2021, ' Flavonoid-based inhibitors of the Phi-class glutathione transferase from black-grass to combat multiple herbicide resistance ', Organic and Biomolecular Chemistry, vol. 19, no. 42, pp. 9211-9222 . https://doi.org/10.1039/d1ob01802g
Organic & Biomolecular Chemistry, 2021, Vol.19(42), pp.9211-9222 [Peer Reviewed Journal]
Schwarz, M, Eno, R F M, Freitag-Pohl, S, Coxon, C R, Straker, H E, Wortley, D J, Hughes, D J, Mitchell, G, Moore, J, Cummins, I, Onkokesung, N, Brazier-Hicks, M, Edwards, R, Pohl, E & Steel, P G 2021, ' Flavonoid-based inhibitors of the Phi-class glutathione transferase from black-grass to combat multiple herbicide resistance ', Organic and Biomolecular Chemistry, vol. 19, no. 42, pp. 9211-9222 . https://doi.org/10.1039/d1ob01802g
The evolution and growth of multiple-herbicide resistance (MHR) in grass weeds continues to threaten global cereal production. While various processes can contribute to resistance, earlier work has identified the phi class glutathione-S-transferase (
Autor:
Gavin John Hall, Eddie McIndoe, Anushka Howell, Melissa Brazier-Hicks, Jonathan Cohn, Tim R. Hawkes, Robert Edwards
Publikováno v:
Journal of Experimental Botany
The closely related sulphonamide safeners, metcamifen and cyprosulfamide, were tested for their ability to protect rice from clodinafop-propargyl, a herbicide normally used in wheat. While demonstrating that both compounds were equally bioavailable i
Autor:
Alina Goldberg-Cavalleri, Rong Ma, Dean E. Riechers, Vijay K. Nandula, David J. Wortley, Nawaporn Onkokesung, Franck E. Dayan, Catherine Tétard-Jones, Melissa Brazier-Hicks, Mithila Jugulam, Michael Barrett, Todd A. Gaines, Yurdagul Ferhatoglu, Satoshi Iwakami, Stephen O. Duke, Robert Edwards
Publikováno v:
Weed Science. 67:149-175
Several grass and broadleaf weed species around the world have evolved multiple-herbicide resistance at alarmingly increasing rates. Research on the biochemical and molecular resistance mechanisms of multiple-resistant weed populations indicate a pre
Publikováno v:
Pest management scienceREFERENCES. 76(7)
BACKGROUND: Anisantha and Bromus spp. are widespread and difficult to control, potentially due to the evolution of herbicide resistance. In this study, UK populations of four brome species have been tested for the early development of resistance to a
Publikováno v:
Plant Biotechnology Journal
Summary Plants contain large numbers of family 1 UDP-glucose-dependent glycosyltransferases (UGTs), including members that conjugate xenobiotics. Arabidopsis contains 107 UGT genes with 99 family members successfully expressed as glutathione transfer
Autor:
Melissa Brazier-Hicks, Robert Edwards
Publikováno v:
Metabolic Engineering. 16:11-20
C-Glycosylated flavonoids are biologically active plant natural products linked to dietary health benefits. We have used polyprotein expression technology to reconstruct part of the respective biosynthetic pathway in tobacco and yeast, such that dihy