Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Melissa Beilschmidt"'
Autor:
Joan Seoane, Patricia Giblin, Jean-Philippe Julien, Judit Anido, Isabel Huber-Ruano, Johan Fransson, Dorothea Maetzel, Melissa Beilschmidt, Alexandre Bosch, Esther Lau, AJ Robert McGray, Almudena Neva-Alejo, Olga Egorova, Peter Bayliss, Swetha Raman, Alexandra Arias, Raffaella Iurlaro, Ester Bonfill-Teixidor, Robin M. Hallett
Supplementary Table 1: Description of TCGA derived mRNA expression cohorts used to examine LIF expression and associated transcript signaturesSupplementary Table 2: Transcription signatures used to identify biological processes and cell types correla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e876e51551f962bd9d5d74e20b1d20a
https://doi.org/10.1158/1078-0432.22482800
https://doi.org/10.1158/1078-0432.22482800
Autor:
Joan Seoane, Patricia Giblin, Jean-Philippe Julien, Judit Anido, Isabel Huber-Ruano, Johan Fransson, Dorothea Maetzel, Melissa Beilschmidt, Alexandre Bosch, Esther Lau, AJ Robert McGray, Almudena Neva-Alejo, Olga Egorova, Peter Bayliss, Swetha Raman, Alexandra Arias, Raffaella Iurlaro, Ester Bonfill-Teixidor, Robin M. Hallett
Supplementary Figure 1. Transcriptomic analysis demonstrates an enrichment of immunological pathways in high LIF tumors. Supplementary Figure 2. LIF transcripts are associated with a panel of immunosuppressive macrophage/myeloid signatures across hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b4731b9846b1639fb87315ef90e1b6
https://doi.org/10.1158/1078-0432.22482803
https://doi.org/10.1158/1078-0432.22482803
Autor:
Joan Seoane, Patricia Giblin, Jean-Philippe Julien, Judit Anido, Isabel Huber-Ruano, Johan Fransson, Dorothea Maetzel, Melissa Beilschmidt, Alexandre Bosch, Esther Lau, AJ Robert McGray, Almudena Neva-Alejo, Olga Egorova, Peter Bayliss, Swetha Raman, Alexandra Arias, Raffaella Iurlaro, Ester Bonfill-Teixidor, Robin M. Hallett
Purpose:Leukemia inhibitory factor (LIF) is a multifunctional cytokine with numerous reported roles in cancer and is thought to drive tumor development and progression. Characterization of LIF and clinical-stage LIF inhibitors would increase our unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b3ecc064e7d4473e93036075979191
https://doi.org/10.1158/1078-0432.c.6530999.v1
https://doi.org/10.1158/1078-0432.c.6530999.v1
Autor:
Robin M. Hallett, Ester Bonfill-Teixidor, Raffaella Iurlaro, Alexandra Arias, Swetha Raman, Peter Bayliss, Olga Egorova, Almudena Neva-Alejo, AJ Robert McGray, Esther Lau, Alexandre Bosch, Melissa Beilschmidt, Dorothea Maetzel, Johan Fransson, Isabel Huber-Ruano, Judit Anido, Jean-Philippe Julien, Patricia Giblin, Joan Seoane
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research.
Purpose:Leukemia inhibitory factor (LIF) is a multifunctional cytokine with numerous reported roles in cancer and is thought to drive tumor development and progression. Characterization of LIF and clinical-stage LIF inhibitors would increase our unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52114ccf48df1069fba559699b7a33bc
https://pubmed.ncbi.nlm.nih.gov/36441800
https://pubmed.ncbi.nlm.nih.gov/36441800
Autor:
Jeanne Magram, Ying Fu, Stephane Angers, Kevin K. Lin, Melissa Beilschmidt, Jean-Philippe Julien, Alejandro Duque, Jason Moffat, Keith Mascall, Francine Lui, Sachdev S. Sidhu, Swetha Raman, Minh D. To, Mark Ng, Yazen Jmeian, Minerva Fernandez, Xiaowei Wang, Guohua Pan, Angus M. Sinclair, Johan E. S. Fransson
Publikováno v:
Proceedings of the National Academy of Sciences. 116:6812-6817
Aberrant activation of Wnt/β-catenin signaling occurs frequently in cancer. However, therapeutic targeting of this pathway is complicated by the role of Wnt in stem cell maintenance and tissue homeostasis. Here, we evaluated antibodies blocking 6 of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2465a558324ba0db09a6e63c504a3055
https://doi.org/10.1073/pnas.1817246116
https://doi.org/10.1073/pnas.1817246116
Autor:
Zainab Haybe, Mark Ng, Melissa Beilschmidt, Minh D. To, Kevin K. Lin, Jeanne Magram, James Pan, Jean-Philippe Julien, Yazen Jmeian, Sachdev S. Sidhu, Johan E. S. Fransson, Stephane Angers, Jason Moffat, Angus Sinclair, Minerva Fernandez, Swetha Raman, Keith Mascall, Ying Fu, Francine Lui
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 74:a297-a297
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b57353fdf1804a157c54bcf4db9c9a2
https://doi.org/10.1107/s0108767318097039
https://doi.org/10.1107/s0108767318097039