Sex and the basal mRNA synthesis machinery

Autor: Diane E. Garsetti, Khushboo Sahay, Yue Wang, Melissa B. Rogers

Publikováno v: Wiley interdisciplinary reviews. RNAREFERENCES.

Evolution and change generated an incredible diversity of organisms on this earth. Yet, some processes are so central to life that change is strongly selected against. Synthesis of the eukaryotic messenger RNA is one example. The assemblies that carr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b1da6875cc445b29921e1224b6e1db
https://pubmed.ncbi.nlm.nih.gov/36195437

MicroRNA Profiles in Calcified and Healthy Aorta Differ: Therapeutic Impact of miR-145 and miR-378

Autor: Edward J. Yurkow, Tapan A. Shah, Ying Tang, Melissa B. Rogers

Publikováno v: Physiological genomics.

Our goal was to elucidate microRNAs (miRNAs) that may repress the excess bone morphogenetic protein (BMP) signaling observed during pathological calcification in theKlothomouse model of kidney disease. We hypothesized that restoring healthy levels of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e28430ec61c7023fef97fc7bb8274e8
https://pubmed.ncbi.nlm.nih.gov/32956022

Competing Repressive Factors Control Bone Morphogenetic Protein 2 (BMP2) in Mesenchymal Cells

Autor: Anastasios Fotinos, Steven Lisica, David T. Fritz, Yijun Liu, Melissa B. Rogers

Publikováno v: Journal of Cellular Biochemistry. 117:439-447

The amount, timing, and location of bone morphogenetic protein 2 (BMP2) synthesis influences the differentiation of pluripotent mesenchymal cells in embryos and adults. The BMP2 3'untranslated region (3'UTR) contains a highly conserved AU-rich elemen

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https://doi.org/10.1002/jcb.25290

Common Cell Lines Used to Study Bone Morphogenetic Proteins (BMPs)

Autor: Sarah Michaels, Jessica Cottrell, Donya Burgess, Melissa B. Rogers

Publikováno v: Methods in Molecular Biology ISBN: 9781493989034

Many research methods exist to elucidate the functions of BMPs during osteogenesis. This chapter briefly reviews common immortalized mesenchymal cell types used to measure the efficacy of osteogenic factors like BMP-2. Detailed information regarding

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https://doi.org/10.1007/978-1-4939-8904-1_1

Calcific Aortic Valve Disease

Autor: Marion A. Hofmann-Bowman, Katherine E. Yutzey, Cecilia M. Giachelli, Douglas P. Mortlock, Elena Aikawa, Gordon S. Huggins, Linda L. Demer, Melissa B. Rogers, Mehran M. Sadeghi, Dwight A. Towler, Simon C. Body

Publikováno v: Calcific Aortic Valve Disease
Yutzey, KE; Demer, LL; Body, SC; Huggins, GS; Towler, DA; Giachelli, CM; et al.(2014). Calcific aortic valve disease: A consensus summary from the alliance of investigators on calcific aortic valve disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 34(11), 2387-2393. doi: 10.1161/ATVBAHA.114.302523. UCLA: Retrieved from: http://www.escholarship.org/uc/item/39k2v9zz
Arteriosclerosis, thrombosis, and vascular biology, vol 34, iss 11
Yutzey, KE; Demer, LL; Body, SC; Huggins, GS; Towler, DA; Giachelli, CM; et al.(2014). Calcific aortic valve disease: A consensus summary from the alliance of investigators on calcific aortic valve disease. Arteriosclerosis, Thrombosis, and Vascular Biology. doi: 10.1161/ATVBAHA.114.302523. UCLA: Retrieved from: http://www.escholarship.org/uc/item/8w7267j0
Arteriosclerosis, Thrombosis, and Vascular Biology, vol 34, iss 11

© 2014 American Heart Association, Inc. Calcific aortic valve disease (CAVD) is increasingly prevalent worldwide with significant morbidity and mortality. Therapeutic options beyond surgical valve replacement are currently limited. In 2011, the Nati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec052c3745f286dd63a1081f09ca0ba9
https://doi.org/10.1161/atvbaha.114.302523