Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Melissa A. Stouffer"'
Publikováno v:
Neurobiology of Disease, Vol 92, Iss , Pp 18-45 (2016)
A wide spectrum of focal, regional, or diffuse structural brain abnormalities, collectively known as malformations of cortical development (MCDs), frequently manifest with intellectual disability (ID), epilepsy, and/or autistic spectrum disorder (ASD
Externí odkaz:
https://doaj.org/article/b59ad6042e0b4acc9bce2b690e10e4e7
Neurons navigate long distances and extend axons to form the complex circuitry of the mature brain. This depends on the coordinated response and continuous remodelling of the microtubule and F-actin networks in the axonal growth cone. Growth cone arc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bcb29a49ec22627d887a4f0e15a7c18
https://doi.org/10.1101/2021.08.06.455451
https://doi.org/10.1101/2021.08.06.455451
Publikováno v:
Acta crystallographica Section D : Structural biology [1993-...]
Acta crystallographica Section D : Structural biology [1993-..], 2018, 74, pp.572-584. ⟨10.1107/S2059798318001948⟩
Acta Crystallographica. Section D, Structural Biology
Acta crystallographica. Section D, Structural biology
Acta crystallographica. Section D, Structural biology, International Union of Crystallography, 2018, 74, pp.572-584. ⟨10.1107/S2059798318001948⟩
Acta crystallographica Section D : Structural biology [1993-..], 2018, 74, pp.572-584. ⟨10.1107/S2059798318001948⟩
Acta Crystallographica. Section D, Structural Biology
Acta crystallographica. Section D, Structural biology
Acta crystallographica. Section D, Structural biology, International Union of Crystallography, 2018, 74, pp.572-584. ⟨10.1107/S2059798318001948⟩
Electron microscopy is a key methodology for studying microtubule structure and organization. Here, the results of cryo-electron tomography experiments on in vitro-polymerized microtubules and comparisons with microtubule ultrastructure in cells are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134b6084da6a0783620e8b1c6cc07a66
https://hal.sorbonne-universite.fr/hal-01822830/document
https://hal.sorbonne-universite.fr/hal-01822830/document
Autor:
J. Messéant, Cyril Gitiaux, F. Bourgeois, E. Kordeli, J.M. Petit, S.M. Sigoillot, Claire Legay, Melissa A. Stouffer, Véronique Bernard, Fiona Francis, Nadia Bahi-Buisson, Perrine Delers
Publikováno v:
Neuromuscular Disorders
Neuromuscular Disorders, Elsevier, 2015, 25 (6), pp.461-473. ⟨10.1016/j.nmd.2015.01.012⟩
Neuromuscular Disorders, Elsevier, 2015, 25 (6), pp.461-473. ⟨10.1016/j.nmd.2015.01.012⟩
Mutations in the microtubule-associated protein doublecortin (DCX) cause type I (X-linked or XLIS) lissencephaly in hemizygous males and subcortical band heterotopia (SBH) in females, with defects in neuron migration during development affecting cort
Autor:
Charles Nicholson, Melissa A. Stouffer, Kenneth D. Carr, Jyoti C. Patel, Margaret E. Rice, Maria Mancini
Publikováno v:
The European journal of neuroscience. 49(6)
Diet influences dopamine transmission in motor- and reward-related basal ganglia circuitry. In part, this reflects diet-dependent regulation of circulating and brain insulin levels. Activation of striatal insulin receptors amplifies axonal dopamine r
Autor:
Virginie Lavilla, Reham Khalaf-Nazzal, Leila Muresan, Melissa A. Stouffer, Audrey Roumegous, Fiona Francis, Robert Olaso, Imane Moutkine, Wassila Carpentier, Hugues Roest Crollius, Benoit Albaud, Sylvie Dumont, Nicolas Cagnard
Publikováno v:
Human Molecular Genetics
Human Molecular Genetics, Oxford University Press (OUP), 2016, 26 (1), pp.90-108. ⟨10.1093/hmg/ddw370⟩
Human Molecular Genetics, 2017, 26 (1), pp.90-108. ⟨10.1093/hmg/ddw370⟩
Human Molecular Genetics, Oxford University Press (OUP), 2016, 26 (1), pp.90-108. 〈10.1093/hmg/ddw370〉
Human Molecular Genetics, Oxford University Press (OUP), 2016, 26 (1), pp.90-108. ⟨10.1093/hmg/ddw370⟩
Human Molecular Genetics, 2017, 26 (1), pp.90-108. ⟨10.1093/hmg/ddw370⟩
Human Molecular Genetics, Oxford University Press (OUP), 2016, 26 (1), pp.90-108. 〈10.1093/hmg/ddw370〉
International audience; Human doublecortin (DCX) mutations are associated with severe brain malformations leading to aberrant neuron positioning (heterotopia), intellectual disability and epilepsy. The Dcx protein plays a key role in neuronal migrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::598cb0245d0298dc4beaae8484293f53
https://hal.sorbonne-universite.fr/hal-01512718
https://hal.sorbonne-universite.fr/hal-01512718
Autor:
Margaret E. Rice, Jyoti C. Patel, Federica Sarti, Melissa A. Stouffer, Solav Ali, Maarten E. A. Reith, Kenneth D. Carr
Publikováno v:
Journal of Neurochemistry. 118:714-720
Dopamine (DA) is an important transmitter in both motor and limbic pathways. We sought to investigate the role of D1-receptor activation in axonal DA release regulation in dorsal striatum using a D1-receptor antagonist, SKF-83566. Evoked DA release w
Autor:
S. Cabeza de Vaca, Melissa A. Stouffer, Lily S. Chau, Edward B. Ziff, David S. Tukey, Sophie Restituito, Kenneth D. Carr, K. Gustafson
Publikováno v:
Neuroscience. 165:1074-1086
Previous findings suggest that neuroadaptations downstream of D-1 dopamine (DA) receptor stimulation in nucleus accumbens (NAc) are involved in the enhancement of drug reward by chronic food restriction (FR). Given the high co-expression of D-1 and G
Autor:
Ralph R. Martel, Melissa A. Stouffer, Roland Stein, Bruce Seligmann, Yan Hang, David M. Harlan, Susanne Pechhold, Gregory Walker, Klaus Pechhold
Publikováno v:
Nature Biotechnology. 27:1038-1042
Cells that have been purified by FACS using intracellular markers are not amenable to gene expression analysis by conventional methods. Pechhold et al. solve this problem with the quantitative nuclease protection assay and apply the approach to study
Autor:
Robert Machold, Melissa A. Stouffer, Margaret E. Rice, Maarten E. A. Reith, Kymry T. Jones, Soledad Cabeza de Vaca, Paul Witkovsky, Jyoti C. Patel, Catherine Woods, Christian R. Lee, Li Bao, Kenneth D. Carr
Publikováno v:
Nature Communications
Insulin activates insulin receptors (InsRs) in the hypothalamus to signal satiety after a meal. However, the rising incidence of obesity, which results in chronically elevated insulin levels, implies that insulin may also act in brain centres that re