Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Melissa A. Reimers"'
Autor:
Yige Wu, Nadezhda V. Terekhanova, Wagma Caravan, Nataly Naser Al Deen, Preet Lal, Siqi Chen, Chia-Kuei Mo, Song Cao, Yize Li, Alla Karpova, Ruiyang Liu, Yanyan Zhao, Andrew Shinkle, Ilya Strunilin, Cody Weimholt, Kazuhito Sato, Lijun Yao, Mamatha Serasanambati, Xiaolu Yang, Matthew Wyczalkowski, Houxiang Zhu, Daniel Cui Zhou, Reyka G. Jayasinghe, Daniel Mendez, Michael C. Wendl, David Clark, Chelsea Newton, Yijun Ruan, Melissa A. Reimers, Russell K. Pachynski, Chris Kinsinger, Scott Jewell, Daniel W. Chan, Hui Zhang, Aadel A. Chaudhuri, Milan G. Chheda, Benjamin D. Humphreys, Mehdi Mesri, Henry Rodriguez, James J. Hsieh, Li Ding, Feng Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-25 (2023)
Abstract Identifying tumor-cell-specific markers and elucidating their epigenetic regulation and spatial heterogeneity provides mechanistic insights into cancer etiology. Here, we perform snRNA-seq and snATAC-seq in 34 and 28 human clear cell renal c
Externí odkaz:
https://doaj.org/article/f1e225c958cf48d29abdb4ad3857630a
Autor:
Pradeep S. Chauhan, Alexander Shiang, Irfan Alahi, R. Taylor Sundby, Wenjia Feng, Bilge Gungoren, Cayce Nawaf, Kevin Chen, Ramandeep K. Babbra, Peter K. Harris, Faridi Qaium, Casey Hatscher, Anna Antiporda, Lindsey Brunt, Lindsey R. Mayer, Jack F. Shern, Brian C. Baumann, Eric H. Kim, Melissa A. Reimers, Zachary L. Smith, Aadel A. Chaudhuri
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-6 (2023)
Abstract Circulating tumor DNA (ctDNA) sensitivity remains subpar for molecular residual disease (MRD) detection in bladder cancer patients. To remedy this problem, we focused on the biofluid most proximal to the disease, urine, and analyzed urine tu
Externí odkaz:
https://doaj.org/article/6c08dcfd52c5447997c27e3e554c3cca
Autor:
Yige Wu, Nadezhda V. Terekhanova, Wagma Caravan, Nataly Naser Al Deen, Preet Lal, Siqi Chen, Chia-Kuei Mo, Song Cao, Yize Li, Alla Karpova, Ruiyang Liu, Yanyan Zhao, Andrew Shinkle, Ilya Strunilin, Cody Weimholt, Kazuhito Sato, Lijun Yao, Mamatha Serasanambati, Xiaolu Yang, Matthew Wyczalkowski, Houxiang Zhu, Daniel Cui Zhou, Reyka G. Jayasinghe, Daniel Mendez, Michael C. Wendl, David Clark, Chelsea Newton, Yijun Ruan, Melissa A. Reimers, Russell K. Pachynski, Chris Kinsinger, Scott Jewell, Daniel W. Chan, Hui Zhang, Aadel A. Chaudhuri, Milan G. Chheda, Benjamin D. Humphreys, Mehdi Mesri, Henry Rodriguez, James J. Hsieh, Li Ding, Feng Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/fd169da4eccd46d28f702fba89461d95
Autor:
Pradeep S Chauhan, Kevin Chen, Ramandeep K Babbra, Wenjia Feng, Nadja Pejovic, Armaan Nallicheri, Peter K Harris, Katherine Dienstbach, Andrew Atkocius, Lenon Maguire, Faridi Qaium, Jeffrey J Szymanski, Brian C Baumann, Li Ding, Dengfeng Cao, Melissa A Reimers, Eric H Kim, Zachary L Smith, Vivek K Arora, Aadel A Chaudhuri
Publikováno v:
PLoS Medicine, Vol 18, Iss 8, p e1003732 (2021)
BackgroundThe standard of care treatment for muscle-invasive bladder cancer (MIBC) is radical cystectomy, which is typically preceded by neoadjuvant chemotherapy. However, the inability to assess minimal residual disease (MRD) noninvasively limits ou
Externí odkaz:
https://doaj.org/article/68ac59a93c0e4cf082db6dfecd686ee0
Autor:
Steven B. Goldenthal, Melissa A. Reimers, Udit Singhal, Mark Farha, Rohit Mehra, Morand Piert, Jeffrey J. Tosoian, Parth K. Modi, Nicole Curci, James Peabody, Eduardo Kleer, David C. Smith, Todd M. Morgan
Publikováno v:
Urology. 167:171-178
To aid in the diagnosis and treatment of patients with metastatic tumor seeding, an exceedingly rare phenomenon following minimally invasive urological surgery, additional case reports are needed.We report our experience with patients determined to h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0298738efb8c6d3f30c414576ef13da
https://doi.org/10.1016/j.urology.2022.04.002
https://doi.org/10.1016/j.urology.2022.04.002
Autor:
Ricardo J. Ramirez, Pradeep S. Chauhan, Bruna Pellini, Andrew M. Davis, Melissa A. Reimers, Jose P. Zevallos, Kevin Chen, Aadel A. Chaudhuri, Misty D. Shields, Peter K. Harris
Publikováno v:
Mol Diagn Ther
The detection of circulating tumor DNA via liquid biopsy has become an important diagnostic test for patients with cancer. While certain commercial liquid biopsy platforms designed to detect circulating tumor DNA have been approved to guide clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4425ac623a7ca30c80e7ffb9294277cf
https://doi.org/10.1007/s40291-021-00559-x
https://doi.org/10.1007/s40291-021-00559-x
Publikováno v:
JCO Precision Oncology. :1133-1140
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b72b8f1be35821c4a96d355daca34b4
https://doi.org/10.1200/po.21.00051
https://doi.org/10.1200/po.21.00051
Autor:
Michael G. Fradley, Adam C. Calaway, Arjun K. Ghosh, Daniel Addison, Brian C. Baumann, Lee Ponsky, Neal L. Weintraub, Jorge A. Garcia, Nihar R. Desai, Jennifer Cullen, Melissa A. Reimers, Courtney M. Campbell, Kathleen W. Zhang, Daniel J. Lenihan, Avirup Guha
Publikováno v:
Journal of Urology. 206:613-622
Purpose:The comparative cardiovascular risk profiles of available hormone therapies for the treatment of prostate cancer is not known.Materials and Methods:We queried the U.S. Food and Drug Adminis...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dec71a9d3edae38dc277e0d923451d9
https://doi.org/10.1097/ju.0000000000001785
https://doi.org/10.1097/ju.0000000000001785
Autor:
Martin W. Schoen, Kenneth R. Carson, Seth A. Eisen, Charles L. Bennett, Suhong Luo, Melissa A. Reimers, Eric M. Knoche, Alison L. Whitmer, Yan Yan, Bettina F. Drake, Kristen M. Sanfilippo
Publikováno v:
Prostate Cancer and Prostatic Diseases.
Background Comorbid diseases influence patient outcomes, yet little is known about how comorbidities interact with treatments for metastatic castrate-resistant prostate cancer (mCRPC). No head-to-head trials have compared the efficacy of abiraterone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0089a0570a4801aa6b567b1ac9cf6330
https://doi.org/10.1038/s41391-022-00588-5
https://doi.org/10.1038/s41391-022-00588-5
Autor:
Melissa A. Reimers, Vadim S. Koshkin, Felix Y. Feng, Hala T. Borno, Alexander W. Wyatt, Steven Yip, Francis Wright, Rahul Aggarwal, Li Zhang, Daniel Kwon, Kim N. Chi, Ajjai Alva, Arpita Desai, Eric J. Small, Mallika Sachdev Dhawan, Jonathan Chou
Publikováno v:
Cancer. 127:1965-1973
Background DNA damage repair mutations (DDRm) are common in patients with metastatic castration-resistant prostate cancer (mCRPC). The optimal standard therapy for this population is not well described. Methods A multi-institutional, retrospective st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdaa4f86493fea6245022706c5b94a21
https://doi.org/10.1002/cncr.33487
https://doi.org/10.1002/cncr.33487