Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Melissa A. Marton"'
Autor:
Melissa A. Marton, Joshua Gould, Alykhan F. Shamji, Levi A. Garraway, Andrew L. Kung, Yan Ling Zhang, Wendy Winckler, Kenneth N. Ross, Pablo Tamayo, Stuart L. Schreiber, Griselda Metta Yvone, Michelle Palmer, Todd R. Golub, Aristotle M. Mannan, Andrew Crenshaw, Aviad Tsherniak, Bang Wong, Michael Foley, Barbara A. Weir, Channing Yu, Bradley Taylor
Publikováno v:
Nature biotechnology
Nature biotechnology, vol 34, iss 4
Nature biotechnology, vol 34, iss 4
Hundreds of genetically characterized cell lines are available for the discovery of genotype-specific cancer vulnerabilities. However, screening large numbers of compounds against large numbers of cell lines is currently impractical, and such experim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d42661725f8e3900a3bb52d9babac5
https://doi.org/10.1038/nbt.3460
https://doi.org/10.1038/nbt.3460
Autor:
C. Suk-Yee Hon, Melissa A. Marton, Nicole E. Bodycombe, Sigrun M. Gustafsdottir, Vebjorn Ljosa, Paul A. Clemons, Vlado Dančík, Stuart L. Schreiber, Ellen Winchester, J. Anthony Wilson, Katherine L Sokolnicki, Joshua A. Bittker, Rajiv Narayan, Todd R. Golub, Wendy Winckler, Kejie Li, Jeremy R. Duvall, George B. Grant, Mathias Wawer, Aravind Subramanian, Mark-Anthony Bray, Melissa M. Kemp, Anne E. Carpenter, Bradley K. Taylor, Alykhan F. Shamji
Publikováno v:
Proceedings of the National Academy of Sciences. 111:10911-10916
High-throughput screening has become a mainstay of small-molecule probe and early drug discovery. The question of how to build and evolve efficient screening collections systematically for cell-based and biochemical screening is still unresolved. It
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c05190eb4d327c3eb9a28cd47962c91
https://doi.org/10.1073/pnas.1410933111
https://doi.org/10.1073/pnas.1410933111